DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6830 and CG31975

DIOPT Version :9

Sequence 1:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	NP_001162840.1	Gene:	CG31975 / 319052	FlyBaseID:	FBgn0051975	Length:	416	Species:	Drosophila melanogaster

Alignment Length:	432	Identity:	110/432 - (25%)
Similarity:	187/432 - (43%)	Gaps:	69/432 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   480 DQIPDWLNIDDFKEIILSAEPNF--EKILSSTSKLATKPGDNFASKLLKVEIEAQLKDNSVKTF- 541
            |::|:   |....|::   ||:.  .::|:..:...||||||:.|.||  .|.|:|:.::.::|
  Fly     4 DKLPE---IRALSEVV---EPHVSGSRLLNYHTSSLTKPGDNYGSVLL--AIHARLQKSNGESFE 60

  Fly   542 -SYILKVHSDNDAINFSDFNLF-PK-----EIEVYSTYVPAFERFYKDVGLPVTFSPKSF----- 594
             ..:.||    ..|:...:..| |:     |..||....||......:.|:|.....|.|
  Fly    61 EQLVAKV----PPIDPKYWQFFQPEQTCLTENAVYKILAPALATLQDEAGVPDESQFKGFPRFYG 121

  Fly   595 ---RLSKDVSK----EYLLLENLQPSGFKMVDRMIGMDLEHSKCTLKKLAQWHAASLKYKELNGP 652
               .|..:.||    ..|:||||:.||:....|:...||.|:...||.:|::||.||..:.|.
  Fly   122 CRESLESNSSKVDQNAVLVLENLRSSGYVSGQRLKAFDLAHTLLALKYMAEFHALSLALRILR-- 184

  Fly   653 YSPKYNNGIFTEQTAPIFKGMFVNT---------KKSFIEEVSKFDGVDEYL-HKMPEILDTYVD 707
              |:    :|.||..|.||....:.         |...:|::.:....|..| .:|.|:.|.:.:
  Fly   185 --PE----VFREQVRPFFKKFDWHAEAPEWKSVMKAETLEDIRRATNNDSRLVARMKELSDQFFE 243

  Fly   708 RILEDAKINEQAFNVLNHGDAWINNIMFQYESDGRVKETLLLDHQVTKYGNPAQDLYYFIMSSTQ 772
            .:.......:..|..:.|.|.|||||||:|...|...|..::|.|..:|.:...|:..|::||..
  Fly   244 FLAAAPDRPDGPFTSIIHCDFWINNIMFRYGPTGTPVELKIIDFQTAQYDSVVHDIISFLLSSVD 308

  Fly   773 LDIKVDQFDYLIRWYHQNMKE-----HAKL--LNYNGFIPSLKELHAILIQHPIFAAGTVLTTLS 830
            ..|...:|::::..|::..:.     .|||  ..:..|...:|.:..|.:.|.||....:|...:
  Fly   309 TAILEVEFEHMLEAYYEAFERCLRRVGAKLEVHTFKEFRLEVKRVAYIQVPHAIFMTRFILADSA 373

  Fly   831 MCLN-------KTTDDFTTDSFLGNEENGKSLREAMFSNERY 865
            :..:       |.||....   .|:|...:.|.:.:...|::
  Fly   374 LIGDSEAEERPKLTDVLKN---TGSERISRKLSQILNLAEKF 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023	87/320 (27%)
CG31975	NP_001162840.1	EcKinase	36..335	CDD:281023	84/312 (27%)
CG31975	NP_001162840.1	APH	<214..329	CDD:279908	29/114 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459617
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840