DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6830 and CG31288

DIOPT Version :9

Sequence 1:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	NP_733094.1	Gene:	CG31288 / 318664	FlyBaseID:	FBgn0051288	Length:	428	Species:	Drosophila melanogaster

Alignment Length:	411	Identity:	137/411 - (33%)
Similarity:	229/411 - (55%)	Gaps:	10/411 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   482 IPDWLNIDDFKEIILSAEPNFEKILSSTSKLATKPGDNFASKLLKVEIEAQLKDNSVKTFSYILK 546
            ||||:|...|:.::...||:..|:|..|...|..||:||.|.:|:|.|:.::||.||||.:||.|
  Fly    16 IPDWINEKYFESVLAKDEPDHVKVLKFTVVAAIPPGENFTSTMLRVYIKLEMKDGSVKTKTYIFK 80

  Fly   547 --VHSDNDAINFSDFNLFPKEIEVYSTYVPAFERFYKDVGLPVTFSPKSFRLSKDVSKEYLLLEN 609
              :..:....:.::|.|||||..:|.||:||||..|||||..:..:||.....:.....:.:.|:
  Fly    81 TMLPEERGGSDINEFGLFPKEAMMYKTYLPAFEALYKDVGWDIQLAPKCLHTEEREGDIHFIFED 145

  Fly   610 LQPSGFKMVDRMIGMDLEH-SKCTLKKLAQWHAASLKYKELNGPYSPKYNNGIFTEQTAPIFKGM 673
            |....||.:||..|:|:|| :|| |:|||::||||..|:||:|||..:::.|...:.........
  Fly   146 LCVKRFKNMDRTKGLDMEHMTKC-LQKLAEYHAASAVYEELHGPYPSEFSEGFVKKDVKKFHVDG 209

  Fly   674 FVNTKKSFIEEVSKF--DGVDEYLHKMPEILDTYVDRILEDAKINEQAFNVLNHGDAWINNIMFQ 736
            |...:|::.:.:..:  ...|:|:...|.: ..|..:.|...::|...|:||||||.|.:|:|..
  Fly   210 FQLKEKAYKKAMLSWGLKDADKYIKAFPTV-KQYWAQCLSTLELNPDEFHVLNHGDFWSSNLMSS 273

  Fly   737 YESDGRVKETLLLDHQVTKYGNPAQDLYYFIMSSTQLDIKVDQFDYLIRWYHQNMKEHAKLLNYN 801
            |..||.:::.:|:|.|:..:|:||.||.:|:..|...|:::.:||:.:|.|.:.:.|..|:|...
  Fly   274 YLPDGTLEKLILIDFQIVMWGSPAMDLLFFLTLSPTNDLRIKEFDHFVRIYWERLVECLKVLKLK 338

  Fly   802 GFIPSLKELHAIL--IQHPIFAAGTVLTTLSMCLNKTTDDFTTDSFLGNEENGKSLREAMFSNER 864
            ..:|.|::|...:  ..|..:|..::|..|.:.|..|..|....:...|.|.|::.|..:.||..
  Fly   339 KPLPKLRDLQNSMNNKNHSFYAFFSILNHLPIILFPTDKDSNIHNLSANTEEGENYRLRLLSNPA 403

  Fly   865 YRANIERVMPWINRRGLLDNF 885
            :...::.:.|::..||:| ||
  Fly   404 FGNVMKDLYPFLYNRGIL-NF 423

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023	103/288 (36%)
CG31288	NP_733094.1	EcKinase	50..331	CDD:281023	100/282 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442526
Domainoid	1	1.000	207	1.000	Domainoid score	I6156
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S12411
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D27900at6960
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.800