DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6830 and CG32195

DIOPT Version :9

Sequence 1:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	NP_001262006.1	Gene:	CG32195 / 317907	FlyBaseID:	FBgn0052195	Length:	401	Species:	Drosophila melanogaster

Alignment Length:	430	Identity:	114/430 - (26%)
Similarity:	199/430 - (46%)	Gaps:	76/430 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   495 ILSAEPNFEKILSST------------SKLATKPGDNFASKLLKVE-IEAQLKDNSVKTFSYILK 546
            |.||| .||:.|:..            .|..::.|:||.|.:.:|. :..:..|.::::..||||
  Fly     5 IYSAE-YFERALARAYGCEMLRVENFHIKAVSQKGENFCSVIYRVALVFRRSPDGALESGKYILK 68

  Fly   547 VHSDNDAINFSDFNLFP-------KEIEVYSTYVPAFERFYKDVGLPVTFSPKSF---RLSKD-- 599
                         :|.|       .|.:::...:||.:...::       :||..   :||.|
  Fly    69 -------------DLLPAAAALGTNEKDMFEVLLPAMQAILEE-------APKEIGEHKLSADCL 113

  Fly   600 -----VSKEYLLLENLQPSGFKMVDRMIGMDLEHSKCTLKKLAQWHAASL----KYKELNGPYSP 655
                 ..||..:||:|...|::..||..|::||.:|..::||||:|.||.    |..||....||
  Fly   114 LVEISAGKELYILEDLGALGYESFDRRQGLNLEEAKICVRKLAQFHGASKVLYEKKPELIQRLSP 178

  Fly   656 K-YNNGI---FTEQTAPIFKGMFVNTKKSFIEEVSKFDGVDEYLHKM-PEILDTYVDRILEDAKI 715
            . |.||:   |.:  |.:.:|. ....::|.||      :.|...|| .:|...|..|:.:....
  Fly   179 SHYANGLNDRFAQ--ALVLEGA-EYAAEAFAEE------LPEISKKMKAQIPKAYTKRMRDVVDP 234

  Fly   716 NEQAFNVLNHGDAWINNIMFQYESDGRVKETLLLDHQVTKYGNPAQDLYYFIMSSTQLDIKVDQF 780
            |:.:.|.:.|||.|:|||||.:.:    |:..|:|.|...:|:||.|||:...:|.:.::.::..
  Fly   235 NKSSLNAVIHGDPWLNNIMFDFVN----KKATLVDFQNCYWGSPAIDLYFLFYTSLKPELLLNNQ 295

  Fly   781 DYLIRWYHQNMKEHAKLLNYNGFIPSLKELHAILIQHPIFAAGTVLTTLSMCL--NKTTDDFTTD 843
            |.|:.:|..|:.|..:...|...:|:..:|...:.:...:...||:..|.:|.  .:.:.||...
  Fly   296 DELLNYYFDNLLETLRHCGYKDTLPTFGQLKDEMKRCLFYGYYTVVCELPICCASPEASVDFGVH 360

  Fly   844 SFLGNEENGKSLREAMFSNERYRANIERVMPWINRRGLLD 883
            :|:..:...|. |..:|::||.|..|:..:...:|.|:|:
  Fly   361 TFVDTDAMLKK-RHQLFASERVRQTIKATLLMFDREGILE 399

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023	86/310 (28%)
CG32195	NP_001262006.1	EcKinase	37..315	CDD:281023	86/310 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459484
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850