DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6830 and CG13360

DIOPT Version :9

Sequence 1:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	NP_569859.1	Gene:	CG13360 / 31025	FlyBaseID:	FBgn0025620	Length:	421	Species:	Drosophila melanogaster

Alignment Length:	404	Identity:	107/404 - (26%)
Similarity:	170/404 - (42%)	Gaps:	82/404 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 PKWLNQTQFEELL-------AADVDQ--FSKIVGFRVKPAMAPGENYATLMLRI---------SI 93
            ||:||:..|:..|       ..|:.:  ||:..|       ..||||.:.:.|.         .:
  Fly    15 PKYLNEDFFKAALEDGLRDMRVDIKKIIFSESSG-------GGGENYCSKIYRAKALYRSSKRQL 72

  Fly    94 DVELTDKSTKLVSFMMKVPHDTPQMEQMMSMANFFTSENAAYTEILPKMEELYKAKGLDIKFAPR 158
            |.||        :.::|....||..:.:..:| .:..|...|.::|.|:|.|.   |...||..:
  Fly    73 DEEL--------ALIVKSIAITPATQFLEELA-VYLREKIFYFDVLGKLEVLI---GDGSKFGAK 125

  Fly   159 AFKLDATKEPKVANTVLMHDLGQNGFKNINRLECLNLEQTKFALTRLAQFHAAGATMVQVHGPYP 223
            .  |..|:||  ..|::..||.|.|:|..:|...||.|.....|.:|.:|||:...:.:......
  Fly   126 C--LYTTREP--IQTIVFDDLTQYGYKLASRQSGLNEEHCVVILKKLGKFHASSMVLAEKEPSVR 186

  Fly   224 DIFVNGVMGNN----KEAIIAFMEGMLASFRTSFMAN-LDKFKNGEEYREKLEKALAGLTMEFMK 283
            :.|..|::..|    .|..|.||     :.:...:|| :.|:...|...|||.:....:....:.
  Fly   187 EHFTTGMLDENYIRTNERFINFM-----TLQCRTLANVVSKWPGYELLAEKLHRHCDNIKENLVT 246

  Fly   284 LGIVDPNEFNALNHGDCWMNNLLFKMNSSGDLE--DMVFVDFQNPKYGSPAMDLLYFIISSVQID 346
            .|...|.|...|||||.|:||.::|.:.....:  |.:||||||..:|||..|:.:|:.||||:|
  Fly   247 TGRPLPGEITVLNHGDLWVNNFMYKYDDEQPTKPIDAIFVDFQNSFFGSPGCDINFFLNSSVQLD 311

  Fly   347 YKLSHFDFFIRHYQEALVKHLGILGFTGRKPSLRELHRTLIK--------------YGGWVLFPT 397
            ..:...:|.|:.|..:|            :.||..:|...:.              ||   .|.:
  Fly   312 VLIHRREFLIQTYYASL------------RDSLERMHSAFVPSYADIQQEIRARELYG---FFSS 361

  Fly   398 ISVLPLVLLDPTQS 411
            .:.||:|.:....|
  Fly   362 YAFLPMVTMKKEDS 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023	87/307 (28%)
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023
CG13360	NP_569859.1	EcKinase	50..335	CDD:281023	89/317 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459222
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850