DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6830 and T16G1.3

DIOPT Version :9

Sequence 1:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	NP_506237.2	Gene:	T16G1.3 / 188553	WormBaseID:	WBGene00011797	Length:	389	Species:	Caenorhabditis elegans

Alignment Length:	369	Identity:	93/369 - (25%)
Similarity:	148/369 - (40%)	Gaps:	79/369 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   501 NFEKILSSTSKL-ATKPGDNFASKLLKVEIEAQLKDNSVKTFSYILKVHSDNDAINFSD-FNLFP 563
            |.|..|...:|. ....|:.|.|:::.||.:..:....:.. .::||:.|....:|..| .||..
Worm     2 NTEARLGENTKFTVVGDGNGFMSRVILVEPDWTVHGEHLPN-RFVLKITSCMHVLNVLDQMNLQD 65

  Fly   564 K-EIEVYSTYVPAFE---------RFYKDVGL----PVTFSPKSFRLSKDVSKEYLLLENLQPSG 614
            | |..::|.:  .:|         ..|:.:|.    .|..|||.|...|..|      |||....
Worm    66 KSESALWSIF--EYEAQGLHNREVNLYEIIGKWNMDDVLMSPKVFFSKKFDS------ENLTKGF 122

  Fly   615 FKM------VDRMIGMDLE----HSKCTLKKLAQWHAASLKY--------------KELNGPYSP 655
            |.|      :.|.:.::|:    ||  .||.||.:.|.|||.              |.:...:|.
Worm   123 FAMEYVDNAITRHLYINLKSYELHS--ILKSLAVFQAESLKLNKREQESVTGYDLEKIVGKMFSQ 185

  Fly   656 KYNNGIFTEQTAPIFKGMFVNTKKSFIEEVSKFD--GVDEYLHKMPEILDTYVDRILEDAKINEQ 718
            ...|.|| ||...|       .|:...|...|..  ||:.....:.:.|:.|:.       |.:
Worm   186 NGLNSIF-EQVRQI-------NKEELSEAADKIAVFGVELVNFDLVKNLNNYLG-------IKK- 234

  Fly   719 AFNVLNHGDAWINNIMFQYESDG-RVKETLLLDHQVTKYGNPAQDLYYFIMSSTQLDIKVDQFDY 782
              |||.|||.|..|||::...|. ||.:  ::|:|....||||:||....:|:.....:...::.
Worm   235 --NVLVHGDLWSANIMWKENKDEFRVDK--IIDYQSIHLGNPAEDLVRLFISTLSGSERQKYWEK 295

  Fly   783 LIRWYHQNMKEHAKLLNYNGFIPSLKELHAILIQHPIFAAGTVL 826
            |:..:::...|..:..|....:..|||.:.:     .|..|::|
Worm   296 LLEQFYEYFIEALEDKNVPYTLEQLKESYRL-----YFVTGSLL 334

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023	82/325 (25%)
T16G1.3	NP_506237.2	PKc_like	1..381	CDD:389743	93/369 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820