DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6830 and H37A05.2

DIOPT Version :9

Sequence 1:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	NP_506379.1	Gene:	H37A05.2 / 186806	WormBaseID:	WBGene00010426	Length:	419	Species:	Caenorhabditis elegans

Alignment Length:	373	Identity:	84/373 - (22%)
Similarity:	146/373 - (39%)	Gaps:	82/373 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 GFRVKPAMAPG--------ENYATLMLRISIDVELTDKSTKLVSFMMKVPHDTPQMEQMMSMANF 127
            ||..|.||...        ||...|..||::.:   .....|.:|...|..:|..:|:|.||.:.
Worm    48 GFMSKIAMIQADWIPRFDTENAQNLPDRIAVKM---SSELSLYNFSTLVSSETWDIEKMKSMTSL 109

  Fly   128 FTSENAAYTEILPKMEELYKAKGLDIKFAP--RAFKLDATKE--PKVANTVL-----MHDLGQNG 183
                   ..|:..:..::|:....:....|  ....|:|..|  |..|..:.     :|.:|.|
Worm   110 -------VKELHNREVDMYRIIMREKPACPTVNVLSLEAFTELSPLKAYIISEYIPNLHHVGMN- 166

  Fly   184 FKNINRLECLNLEQTKFALTRLAQFHAAGATMVQ---VHGPYPDIFVNGVMGNNKEAIIAFMEGM 245
                   :|:::|:....:..:|.|.|.|.:|.:   ......:|::       :||:..|.:..
Worm   167 -------DCISIEEIWAVVDGIAAFSAMGESMSEDEKKKSTIGEIYI-------EEAVKYFFDDQ 217

  Fly   246 LA-SFRTSFMANLDKFKNGEEYREKLEKAL------AGLTMEFMK--------LGIVDPNEFNAL 295
            .. :.|.:.:..|     |..|.||:|:|:      .| :.|..|        ||     ....|
Worm   218 SPDNMRKNLIMIL-----GVAYEEKVEEAMDIFDLYCG-SSEIQKNYSRVSAFLG-----HSPVL 271

  Fly   296 NHGDCWMNNLLFKMNSSGDLEDMVFVDFQNPKYGSPAMDLLYFIISSV-QIDYKLSHFDFFIRHY 359
            .|.|.|.:||||.::|...||....:|||.....||.:|:....::.: :.|.:....:...|:|
Worm   272 MHSDIWPSNLLFSLSSENKLEFKALIDFQTASLSSPGLDVGCLTVTCLSKKDRRTVQSEILDRYY 336

  Fly   360 QEALVKHLGILGFTGRKPSLRELHRTLIKYGGWVLFP--TISVLPLVL 405
             ::.||.|       :.|:.....|..::....:.||  .|.:||.:|
Worm   337 -KSFVKSL-------KTPNSIPYTREQLEDSYELCFPASVILMLPFIL 376

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023	71/327 (22%)
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023
H37A05.2	NP_506379.1	DUF1679	3..409	CDD:369592	84/373 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910