DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6830 and H06H21.8

DIOPT Version :9

Sequence 1:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	NP_001023255.1	Gene:	H06H21.8 / 186700	WormBaseID:	WBGene00019164	Length:	388	Species:	Caenorhabditis elegans

Alignment Length:	404	Identity:	87/404 - (21%)
Similarity:	167/404 - (41%)	Gaps:	75/404 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   488 IDDFKEIILSAEP---NF-EKILSSTSKLATKPGDNFASKLLKVEIEAQLKDNSVKTFSYILKVH 548
            :...:.::.|:.|   || ||:.:|..||  :...:|.|::....::. :.|......|..:||.
Worm     5 LKQLRRLVESSFPEIENFHEKVDASFEKL--ENAKSFWSEIYVAHLKV-VGDGVKVPESVFIKVP 66

  Fly   549 ---------SDNDAIN-FSDFNLFPKEIEVYSTYVPAFERFYKDVGLPVTFSPKSFRLSKDVSKE 603
                     .|..|:| .:|..|:      ||.....|.:.::...:|....||.: .::|::.|
Worm    67 RISENVLRCEDESAVNHLNDVLLY------YSKKENLFYKHFEYGSIPNFPFPKVY-FTEDINGE 124

  Fly   604 Y---LLLENLQPSGFKMVDRMIGMDLEHSKCTLKKLAQWHAASLKYKELNGPYSPKYNNGIFTEQ 665
            .   ::.|||....| .|:.:.|:..|.....::.||..|:..:|..:.:  |...:..|....:
Worm   125 ATGGIVAENLSEKVF-AVEHIPGLKHEQILRLMEALAGLHSFLMKRDDKS--YVESFVEGAHGRE 186

  Fly   666 TAPIFKGMFVNTKKSFIEEVSKFDGVDEYLHKMPEILDTYVDRILE-----DAKINEQAF----- 720
            |  ..:||    :....||....:.|.      ||:...  |||..     |..|..:|.
Worm   187 T--FSEGM----QNMMFEEALTLENVS------PEVFGN--DRIRNIKWSFDYSIKNKATADAIS 237

  Fly   721 ---NVLNHGDAWINNIMFQYESDGRVKETLLLDHQVTKYGNPAQDLYYFIMSSTQLDIKVDQFDY 782
               .::.|.|..:.|::::.:| .:.:.:.::|:|:...|:.|.|:...:......:|:......
Worm   238 AFPGIICHADLNVTNVLWKKDS-AKDEISAIIDYQMLFIGSIAFDIIRVLTLGLNREIRRKMTQN 301

  Fly   783 LIRWYHQNMKEHAKLLNYNGFIP-SLKE-LHAILIQHPIFAAGTVLTTLSMCLNKTTDDFTTDSF 845
            .:..||:.:.|.:     ||..| |::| ||...:.:| |::...|..:::.:.     ..:|..
Worm   302 YLDHYHKTLTELS-----NGKAPFSMEELLHQYSLIYP-FSSNFSLFGIALYIK-----MYSDGT 355

  Fly   846 LGN----EENGKSL 855
            |||    |||.|.|
Worm   356 LGNPEDKEENCKEL 369

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023	59/309 (19%)
H06H21.8	NP_001023255.1	CHK	129..312	CDD:214734	39/200 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910