DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6830 and F20D6.5

DIOPT Version :9

Sequence 1:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	NP_505104.3	Gene:	F20D6.5 / 184724	WormBaseID:	WBGene00017635	Length:	376	Species:	Caenorhabditis elegans

Alignment Length:	353	Identity:	70/353 - (19%)
Similarity:	132/353 - (37%)	Gaps:	113/353 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   517 GDNFASKLLKVEIEAQLKDNSVKTFSYILKVHSDNDAINFSDFNLFPKEIEVYSTYVPAFERFYK 581
            ||:...||...|::|         ::::.|         |||.|:             ::.:.|:
Worm    65 GDDTFCKLHNTEVDA---------YTFLQK---------FSDKNI-------------SYPKIYE 98

  Fly   582 DVGLPVTFSPKSFRLSKDVSKEYLLLE------------NLQPSGFKMVDRMIGMDLEHSKCTLK 634
            ...:.::..|        :.:.::::|            ||:|      |.:|.        .:|
Worm    99 LEKMDISVDP--------IKQGHIIMEYMSGITHLYCYNNLKP------DELIE--------PVK 141

  Fly   635 KLAQWHAASLKYKELNGPYSPK-----YNNGIFTEQTAPIFKGMFVNTKKSFI------EEVSKF 688
            .||::|:...:..|..|...|:     :...:||:|....|.|.:......::      :.:.:.
Worm   142 NLARFHSIGAELDEEEGSNVPRDFLSSWFTTLFTQQNKNTFIGNWKGDLSDWLPSKVARDTIKEL 206

  Fly   689 DGVDEYLHKMPEILDTYVDRILEDAKINEQ-----AFNVLNHGDAWINNIMFQYESDGRVKETLL 748
            ||:     ..|||.          .|:|..     ...||.|||...:|::::...||..|...:
Worm   207 DGL-----LTPEIF----------LKLNNDCQLTGVQEVLCHGDYSFHNLLYEKHCDGSYKFRAI 256

  Fly   749 LDHQVTKYGNPAQDLYYFIMSSTQLDIKVDQFDYLIRWYHQNMKEHAK-----------LLNYNG 802
            :|.|...:||.||||....:::.....:.|..|.|::.|:..:.:.:|           ..:|..
Worm   257 VDFQSVNWGNAAQDLSRLFVTAMSGKDRRDSEDRLLKIYYDELIKVSKGNVAPFTWEQLKQSYTR 321

  Fly   803 FIPSLKELHAILIQHPIFAAGTVLTTLS 830
            |.    :|||.::  .....|..|.|||
Worm   322 FF----QLHAAIV--CTVTPGLFLVTLS 343

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023	60/321 (19%)
F20D6.5	NP_505104.3	PKc_like	11..369	CDD:389743	70/353 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	53	1.000	Domainoid score	I7597
eggNOG	1	0.900	-	-		E1_2AMXB
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S12411
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.760