DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6830 and E02C12.6

DIOPT Version :9

Sequence 1:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	NP_505426.2	Gene:	E02C12.6 / 183987	WormBaseID:	WBGene00017092	Length:	419	Species:	Caenorhabditis elegans

Alignment Length:	412	Identity:	80/412 - (19%)
Similarity:	161/412 - (39%)	Gaps:	87/412 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   483 PDWLNIDDFKE--IILSAEPNFEKILSSTSKLATKPGDN-FASKLLKVEIEAQLKDNSVKTFSYI 544
            |||.|::|.|:  :..:.:.:.:..|.:.||:....|.| |..:.||...:...|.::::..:|
Worm    58 PDWQNVEDGKKLPVRFALKISSQLALVALSKMLNFGGGNGFTEEKLKKFSKLTRKSHNIEVETY- 121

  Fly   545 LKVHSDNDAINFSDFNLFPKEIEVYSTYVPAFERFYKDVGLPVTFSPKSFRLSKDVSKEYLLLEN 609
             ||        .:.||                   :.|:.....:|.|.|. .:|..|.||:.:.
Worm   122 -KV--------LTKFN-------------------HPDIPYTKVYSLKPFN-GEDDLKGYLITDF 157

  Fly   610 LQPSGFKMVDRMIGMDLEHSKCTLKKLAQWHAASLKYKELNGPYSPKYNNGIFTEQTAPIFKGMF 674
            :  ....:::....:..::...|::.:|.:.|.:   :.|.......:.:..|.|.   :|:..|
Worm   158 I--PNVHVIEAYKSIPADNIAATIRGIATFSALA---EHLEREEQKSFMSTDFLEL---LFEDFF 214

  Fly   675 VNTK--KSFIEEVSKFDGVD--EYLHKMPEILDTYVDRILEDAKINE--QAFNVLNHGDAWINNI 733
            .:.:  |.|....:||:|..  |.:.|:.::...|...:.:...|::  ....|..|||.|.:||
Worm   215 TDAELSKKFEALKTKFEGQQHAEKVSKLIKVFAHYKALVKKYTNISDLLGLKPVFIHGDLWQSNI 279

  Fly   734 MFQYESDGRVKETLLLDHQVTKYGNPAQDLYYFIMSSTQLDIKVDQFDYLIRWYHQNMKEHAKLL 798
            ||..::..::|...::|.|......|..||...::.......:.::...|::.||:.   :||:.
Worm   280 MFTLDNSKKLKLEAIIDWQSVSRIPPGIDLSRIMLGCLSAQERRERGTELLKLYHET---YAKVF 341

  Fly   799 ------------NYNGFIPSLKELHAILIQHPIFAAGTVLTTLSMCLNKTTDDFTTDSFLGNEEN 851
                        :||.:.|.:..|              :|.:||        .|...:.:..||.
Worm   342 GKELFTFQELQDSYNLYAPMMAML--------------ILPSLS--------SFLDSAQISKEEK 384

  Fly   852 GKSLREAMFSNERYRANIERVM 873
            ..:..|.   |.:..|.||.::
Worm   385 AAAAEEV---NLKEVAMIEDIL 403

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023	56/302 (19%)
E02C12.6	NP_505426.2	DUF1679	3..410	CDD:369592	80/412 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810