DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6830 and AgaP_AGAP008987

DIOPT Version :9

Sequence 1:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	XP_319737.4	Gene:	AgaP_AGAP008987 / 1279949	VectorBaseID:	AGAP008987	Length:	418	Species:	Anopheles gambiae

Alignment Length:	471	Identity:	109/471 - (23%)
Similarity:	198/471 - (42%)	Gaps:	97/471 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 PEPPAPPNKPEPEVDHSDLVPKWLNQTQFEELLAADVDQFSKIVGFRVKPAMAPGENYATLMLRI 91
            |..|.||.:        ||          |.|||..:...::::|:..:...|||:||.:.||.:
Mosquito     2 PTVPPPPIR--------DL----------EGLLAPVLPAGTRVLGYESEYLTAPGDNYGSTMLAV 48

  Fly    92 SIDVELTDKST-------KLVSFMMKVPHDTPQMEQMMSMANFFTSENAAYTEILPKMEELYKAK 149
                  ||.|:       :|:..:.|:...:.:..::..:...|..|.|.|.:|:|.:..|.:.:
Mosquito    49 ------TDNSSNDDQPPIELLHLVAKMRPSSEEFLEIFQIDITFVKEAAVYLKIVPSLLALQREQ 107

  Fly   150 GLD-----IKFAPRAFKLDATKEPKVA-----NTVLMHDLGQNGFKNINRLECLNLEQTKFALTR 204
            |.|     |....|.|....:.:|.|.     ..:|..:|...|:...:|.:..|.|..::.|.:
Mosquito   108 GFDGDGELIDVFCRCFNARVSLDPAVEKVDQDGVMLFENLKLAGYVTADRRKGFNRELARYVLKK 172

  Fly   205 LAQFHAAGATMVQVHGPYPDIFVNGVMGNNKEAIIAFMEGMLASFRTSFMANLDKFKNGEEYREK 269
            ||.|||....:..:.   ||:|..|:   :|..:...::..|:  :.:....:|.|:. :..|..
Mosquito   173 LALFHAIPIALRYLK---PDVFETGI---HKYLVKIDIDAGLS--QATLRQMMDVFRQ-DILRTG 228

  Fly   270 LEKALAGLTMEFMKLGIVDPNE---------------FNALNHGDCWMNNLLFKMNSSGDLE-DM 318
            :|..|||  ..:.|:     ||               :..:.|.|.|:||::.|.:.:|.:. .:
Mosquito   229 VEAGLAG--RAYAKI-----NECHRRQAQLISDQLTCYCTMLHNDLWVNNMMIKYDPTGQVPCSL 286

  Fly   319 VFVDFQNPKYGSPAMDLLYFIISSVQIDYKLSHFDFFIRHYQEALVKHLGILGFTGR-KPSLREL 382
            .|||||..:..|...|:::|||:||......:..|.:..:|.:.|..:|..|.|..: :.:|...
Mosquito   287 KFVDFQLIQMDSLVRDVIFFIITSVNDPELEAQLDGYFEYYFQQLAANLARLQFPSQDELTLESF 351

  Fly   383 HRTLIKYGGWVLFPTISVLPLVLLD----PTQSATFDNFMSDSADGVSFRGSLYANKRC--QEYI 441
            ...:.:...:.|:..:|:|.:||..    |.||.      .|:|        |:.|...  ::|.
Mosquito   352 REEIDRVAPFELYHIVSMLRVVLARKESIPDQSE------QDAA--------LFFNDNLVEEDYY 402

  Fly   442 ERI---LPWLDNRGFL 454
            .|:   |...|.||::
Mosquito   403 RRLEVTLRIYDQRGWI 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023	77/324 (24%)
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023
AgaP_AGAP008987	XP_319737.4	EcKinase	37..340	CDD:281023	77/324 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810