DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6830 and AgaP_AGAP010766

DIOPT Version :9

Sequence 1:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	XP_318542.4	Gene:	AgaP_AGAP010766 / 1278896	VectorBaseID:	AGAP010766	Length:	411	Species:	Anopheles gambiae

Alignment Length:	444	Identity:	106/444 - (23%)
Similarity:	200/444 - (45%)	Gaps:	73/444 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   477 ENTDQIPDWLNIDDF------------KEIILSAEPNFEKILSSTSKLATKPGDNFASKLLKVEI 529
            |.||.|   ..:||.            |.::........:|:......||..|||:.|.:.::.:
Mosquito     3 ERTDTI---AGLDDIAVPEYIDERLAAKALVNGLGLQSVRIVECKITRATANGDNYMSDVFRLAV 64

  Fly   530 EAQLKDNSVKTFSYILKVHSDNDAINFSDFNLFPKEIEVYSTYVPAFERFYKDVGLPVTFSPKSF 594
            .            |:.:...|...|:..   .:.||..::...|||.    .::...:.|:.:.|
Mosquito    65 R------------YVAEQSGDERTISLV---AYTKEATMFRDVVPAL----SELTGGMFFAARCF 110

  Fly   595 RLSKDVSKEYLLLENLQPSGFKMVDRMIGMDLEHSKCTLKKLAQWHAASLKYKELN--------- 650
            ..| |:.:..|:.|:|:..|:..|:|..|:|.||....::|:.|:||||:::.|..
Mosquito   111 YAS-DLPERLLVFEDLKALGYVTVNRQAGLDFEHCALVMRKIGQFHAASMRFAEQRLELLQRQFH 174

  Fly   651 -GPYSPKYNNGIFTEQTAPIF-KGMFVNTKKSFIEEV-SKFDGVDE-YLHKMPEILDTYVDRI-- 709
             ..::|  ::|..:.|...|| ||:     ::.|... .::||.|: .:.|:..:...|:||:
Mosquito   175 FNMFNP--DHGEASGQLRTIFEKGL-----EALIAVARERWDGFDQTIVQKLERLAPVYIDRLRA 232

  Fly   710 -LEDAKINEQAFNVLNHGDAWINNIMFQYE--SDGRVKETLLLDHQVTKYGNPAQDLYYFIMSST 771
             ||.....:..:.||||||.|.||::|:|:  ....|::...:|.|::.|.:|..||.|.:.:..
Mosquito   233 CLEQDCEADGGYRVLNHGDLWSNNMLFRYDPTEPATVQDVAFVDLQISFYSSPGVDLNYVLATCP 297

  Fly   772 QLDIKVDQFDYLIRWYHQNMKEHAKLLNYNGF-IPSLKELHAILIQHPIFAAGTVLTTLSMCLNK 835
            ..|.:. :.|.||..|:.:.::..:.|.|... ||||.::...:.:...:|..:|::.|.:.:..
Mosquito   298 NYDTRA-RLDELIELYYASFRDTLEQLQYTARPIPSLADVRREIRRMEFYALVSVVSVLPIVVMD 361

  Fly   836 TTDDFTTDSFLGNEEN---GKS---LREAMFSNERYRANIERVMPWINRRGLLD 883
            .||:     .:.|.||   ||.   .|:..::...|:..:..::...|:|.:||
Mosquito   362 HTDE-----LVANFENLIDGKDAARARDIQYNGVNYQRIVRPMLIEFNQRKMLD 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023	75/301 (25%)
AgaP_AGAP010766	XP_318542.4	EcKinase	51..325	CDD:281023	75/301 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820