DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6830 and AgaP_AGAP003236

DIOPT Version :9

Sequence 1:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	XP_312943.4	Gene:	AgaP_AGAP003236 / 1273909	VectorBaseID:	AGAP003236	Length:	441	Species:	Anopheles gambiae

Alignment Length:	315	Identity:	77/315 - (24%)
Similarity:	141/315 - (44%)	Gaps:	57/315 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   518 DNFASKLLKVEIEAQLKDNS-VKTFSYILKVHSDNDAINFSDF--NLFPKEIEVYSTYVPAFERF 579
            |.|.|.:.|:....:..|.: |:|...::||...:|....|..  ..|..||.:|:..:|||:..
Mosquito    43 DGFMSTIHKLSFRYESNDGTVVQTLKLMVKVMKGSDEFRESSMGKTQFTNEIYIYTKVLPAFQEL 107

  Fly   580 YKDVGLPVTFSPK-------SFRLSKDVSKEYLLLENLQPSGFKMVDRMIGMDLEHSKCTLKKLA 637
            ..|.||...:.|:       .|....|..:..|:||::.|.|:|...| :.::.||.:...:.:|
Mosquito   108 LTDSGLAGDWCPRVYYGEAGHFPTYSDQYETILVLEDISPLGYKAGPR-LDLEEEHLRLMARHIA 171

  Fly   638 QWHAASLKYKELNGPYSPKYNNGIFTEQTAPIFKGM----FVNTKKSFIEEVSKFD-----GVD- 692
            .:||.:         |:.:..|   ..:.|.:.:|:    ||:..|:|    :.:|     |.:
Mosquito   172 SFHACT---------YAMRLRN---DARLASLIEGIAPLDFVSGDKTF----TSYDVLLKLGANR 220

  Fly   693 --EYLHKMPEILDTYVDR----------------ILEDAKINEQAFNVLNHGDAWINNIMFQYES 739
              :||...||.||:...:                :::|....::.|:|:.|||...||::|:.:.
Mosquito   221 LYKYLDDHPEQLDSEAFKRDMNNLRQRYGTTPISLMQDLLRKDETFSVILHGDYNRNNVLFRADG 285

  Fly   740 DGRVKETLLLDHQVTKYGNPAQDL-YYFIMSSTQLDIKVDQFDYLIRWYHQNMKE 793
            .|:..|..:.|.|..:|..|..|| :|..||.|: :::...:|.::..||..:.|
Mosquito   286 AGKPVELKMFDFQENRYATPVIDLTFYMYMSMTE-ELRNRCWDAIVLEYHTALLE 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023	77/315 (24%)
AgaP_AGAP003236	XP_312943.4	PKc_like	43..341	CDD:304357	77/315 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910