DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6830 and AgaP_AGAP003855

DIOPT Version :9

Sequence 1:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	XP_310414.7	Gene:	AgaP_AGAP003855 / 1271592	VectorBaseID:	AGAP003855	Length:	428	Species:	Anopheles gambiae

Alignment Length:	424	Identity:	123/424 - (29%)
Similarity:	186/424 - (43%)	Gaps:	55/424 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 LNQTQFEELLAADVDQFSKIVGFRVKPAMAP-GENYA-TLMLRISIDVELTDKSTK-LVSFMMKV 111
            |.|||:.|   .:|    ||..:.|:||.|. .:.|| :.|.||.|.....:..|: :::|:.|:
Mosquito    18 LIQTQYGE---TEV----KIKAYDVEPASADINDPYARSSMNRILIKYTSKENPTEAVITFVAKI 75

  Fly   112 PHDTPQMEQMMSMANFFTSENAAYTEILPKMEELYKAKGLDIKFAPRAFKLDATKEPKVANTVLM 176
            ......:.:....|:.|..|...|..:||.|..:....|..|:.||:......|.    ::.|::
Mosquito    76 KPTEGLLVEQFKKADVFEKEILMYKSVLPSMVTMIAKLGSVIELAPQLIYSSETP----SDLVVL 136

  Fly   177 HDLGQNGFKNINRLECLNLEQTKFALTRLAQFHAAGATMVQVHGPYPDIFVNGVM-GNNKEAIIA 240
            .||...|:...|:...|:.||:|.|:.:||.||||.|.|:..:|.....|..|.. ..:|:.:..
Mosquito   137 EDLTARGYSVENQTLGLSYEQSKMAVEKLAFFHAASAMMLSENGQAFPKFTKGTFHAEHKDKLSY 201

  Fly   241 F-----MEGMLASFRTSFMANLDKFKNGEEYREKLEKALAGLTMEFMKLGIVDPNEFNALNHGDC 300
            |     |.|.:|       |.||   ..:...:||.|..|....:.::....|...|..|||||.
Mosquito   202 FPDTIRMVGEMA-------AELD---ISQPMADKLLKLPAKALQKAIEAYESDFKGFKVLNHGDF 256

  Fly   301 WMNNLLFKMNSSGDLEDMVF---VDFQNPKYGSPAMDLLYFIISSVQIDYKLSHFDFFIRHYQEA 362
            |.||:|||...: :|.|..|   |||||...|||.:||:||:.:|...:....|.|..:..|.|.
Mosquito   257 WTNNILFKYQGN-ELVDANFVRVVDFQNCVVGSPIIDLVYFLAASPAHEVLEKHRDELVYIYHET 320

  Fly   363 LVKHLGILGFTGRKPSLRELHRTLIKYGGWVLFPTISVLPLV--------------LLDPTQSAT 413
            ||..|..:|:....|||.||...|:|:|...:...::|.|.:              |..|.||..
Mosquito   321 LVLLLQKMGYMKSIPSLLELQVELLKHGSLQVIYALTVSPFMRTKDAHNTPPMQPTLHSPNQSTN 385

  Fly   414 FDNFMSDSADGVSFRGSLYANKRCQEYIERILPW 447
            ....:...|.      |:.|..:..|.: .:|.|
Mosquito   386 VKQVLRAHAP------SIVAQLKAYEMV-GLLDW 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023	90/303 (30%)
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023
AgaP_AGAP003855	XP_310414.7	PKc_like	44..330	CDD:304357	90/300 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920