DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6830 and AgaP_AGAP012604

DIOPT Version :9

Sequence 1:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	XP_307590.4	Gene:	AgaP_AGAP012604 / 1269011	VectorBaseID:	AGAP012604	Length:	417	Species:	Anopheles gambiae

Alignment Length:	432	Identity:	104/432 - (24%)
Similarity:	186/432 - (43%)	Gaps:	99/432 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 DQFSKIVGFRVKPAMAP------GENYATLMLRISIDVELTDKSTKLVSFMMK-VPHDTPQMEQM 121
            ||..:||...::| .:|      .::||   |:::|:   .:..|:|:||.:| :|.:.|.:...
Mosquito    28 DQAYRIVQTALEP-FSPCPEGFLADHYA---LKVTIE---RNGQTELLSFFVKCLPTENPVLRSY 85

  Fly   122 MSMANFFTSENAAYTEILPKMEELYKAKGLDIKFAPRAFKLDATKEPKVANTVLMHDLGQNGFKN 186
            :.....|..|::....|:..::.....:.:    |||...  |.:|    ..::|::|..:|:..
Mosquito    86 LEEIGSFRKESSVLQRIVGSIQRHCPWRTV----APRVHL--AVEE----QLLVMNNLKSDGYSV 140

  Fly   187 INR----LECLNLEQTKFALTRLAQFHAAGATMVQVHGP-YPDIFVNGVMGNNKEAIIAFMEGML 246
            :.|    ||.:.:.|   ||..|:..||....:.|..|. .|::|.. |:..|     |::: ..
Mosquito   141 VKREGGLLEVVFVHQ---ALETLSNLHACSFVLEQKQGKRLPELFPT-VLNEN-----AWVQ-TS 195

  Fly   247 ASFRTSFMANLDKFK----------NGEEYREKLEKALAGLTMEFMKLGIVDP-NEF-NALNHGD 299
            .|.|...:||:.|..          :|...:..||: ||.|..:...  .|:| :|| |.|||||
Mosquito   196 TSTRVKDVANVIKLYTELVKICDHWHGPRKQTILER-LAPLIRKIYT--YVEPSHEFRNCLNHGD 257

  Fly   300 CWMNNLLFKMNSSGDLEDMVFVDFQNPKYGSPAMD--LLYFIISSVQI-DYKLSHFDFFIRHYQE 361
            .|.||::||.:..|.......||:|..:|..||.|  ||.::.:|.|: |..|:   ..:.||.:
Mosquito   258 LWCNNIMFKCDGQGQPIGCALVDYQLSRYVPPAYDINLLLYLTTSRQLRDENLT---ALLDHYYK 319

  Fly   362 ALV-----------------------KHLGILGFTGRKPSLRELHRTLIKYGGWVLFPTISVLPL 403
            ..|                       :|..:.|.         :|.|:|  .|.|..|: ..|..
Mosquito   320 CFVDTLERNQVNASEIYPRETFLRCCEHYRLAGL---------IHSTII--SGEVTLPS-KFLEE 372

  Fly   404 VLLDPTQSATFDNFMSDSADGVSFRGSLYANKRCQEYIERIL 445
            :..|...:|   :||.|:...:..: :..|::|.::::..:|
Mosquito   373 IFGDLQSTA---SFMPDTKVWICVK-AFQADERYRKHLIELL 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023	83/341 (24%)
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023
AgaP_AGAP012604	XP_307590.4	PKc_like	51..327	CDD:304357	81/307 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810