DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6830 and AgaP_AGAP012996

DIOPT Version :9

Sequence 1:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	XP_003435872.1	Gene:	AgaP_AGAP012996 / 11176009	VectorBaseID:	AGAP012996	Length:	446	Species:	Anopheles gambiae

Alignment Length:	456	Identity:	104/456 - (22%)
Similarity:	183/456 - (40%)	Gaps:	80/456 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   461 LPPELLAALKPQQPQPENTDQIPDWLNIDDFKEIILSAEPNFEKILSSTSKLATKPGDNFASKLL 525
            ||..|.||||...|:             :.|.|...:.|.:|     .:||     ||.|..::.
Mosquito    37 LPAYLHAALKQLAPK-------------EGFTEGNFTIEFDF-----GSSK-----GDGFVGQMF 78

  Fly   526 KVEI-EAQLKDNSVKTFSYILKVHSDNDA--INFSDFNLFPKEIEVYSTYVPAFERFYKDVGL-- 585
            |..| |...::      .|:.|:...:||  ..||....|.:|:.||..::|....:.:..|:
Mosquito    79 KATISEGDRRE------VYLCKIPPLDDARREQFSSMAAFAREVLVYDRFLPTIYEYQRAKGILG 137

  Fly   586 ---PVTFSPKSF--RLSKDVSKEYLLLENLQPSGFKMVDRMIGMDLEHSKCTLKKLAQWHAASLK 645
               ....:|:.:  ...:...:..:::|:|:...|::.::...:|..|....:..|.:.||.||.
Mosquito   138 RDDGFFHTPRCYLAHCDETAQESVIIMEDLRLREFQLWNKHNIIDYAHGTLFMTHLGRLHAISLA 202

  Fly   646 YK----------ELNGPYSPKYNNGIFTEQTAPIFKGMFVNTKKSFIEEVSKFDGVDEYLHKMPE 700
            .|          :|..|:.|      ..:...| |:.|.::..:..|:.:.:.|.::.  .||.:
Mosquito   203 MKRDQPERFAPFKLPNPFDP------MLKADGP-FRNMILSQLQMVIDALREQDTIER--AKMEQ 258

  Fly   701 ILDTYVDRILEDAKIN-EQAFNVLNHGDAWINNIMFQYESDGRVKETLLLDHQVTKYGNPAQDLY 764
            :.:...|.:....|.. .:.:.|:.|||.|.||:||:|| :|..||.:|.|.||.:|..|.|||.
Mosquito   259 LKEDVFDELARCGKAELAEPYAVVGHGDCWTNNMMFRYE-EGIPKEIVLFDWQVMRYVTPVQDLM 322

  Fly   765 YFIMSSTQLDIKVDQFDYLIRWYHQNMKEHAKLLNYNGFIPSLKEL--HAILIQHPI------FA 821
            |||...|..:.:...:..:|..|:.::......|.::.     .||  .|:|.:..:      ..
Mosquito   323 YFIFCCTDGEFRRKYYHEMIDIYYDSLSTMLTKLQHDA-----SELFPRAVLDEQLLVFGRYGIL 382

  Fly   822 AGTVLTTLSMCLNKTTDDFTTDSFLGNEENGKSLREAMF-----SNERYRANIERVMPWINRRGL 881
            .|..|..:....|....|.  ::........:.|.|:.|     :.|.|...|..|:....|.|.
Mosquito   383 MGMFLVPMMCTRNDELPDI--EALAQKMTETQQLDESFFKTTESNQEAYATRIRSVVQDSIRYGY 445

  Fly   882 L 882
            |
Mosquito   446 L 446

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023	72/304 (24%)
AgaP_AGAP012996	XP_003435872.1	EcKinase	69..358	CDD:281023	73/309 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810