DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6830 and AgaP_AGAP013201

DIOPT Version :9

Sequence 1:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	XP_003436598.1	Gene:	AgaP_AGAP013201 / 11175923	VectorBaseID:	AGAP013201	Length:	408	Species:	Anopheles gambiae

Alignment Length:	415	Identity:	113/415 - (27%)
Similarity:	208/415 - (50%)	Gaps:	26/415 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   484 DWLNIDDFKEIILSAE--PNFEKILSSTSKLATKPGDNFASKLLKVEIEAQLKDNSVKTFSYILK 546
            :|:| :|....:||.:  .:|:::::.....|||.|||:||::.:|.::..: .|.||. ..|||
Mosquito     5 EWIN-NDLLTGLLSEQHGTSFKRLIAYDVSFATKKGDNYASEMYRVSVQYDI-GNIVKK-RIILK 66

  Fly   547 VHSDNDAIN--FSDFNLFPKEIEVYSTYVPAFERFYKDVGLPVTFSPKSFRLSKDVSKEYLLLEN 609
            |....:...  ..:.:::.:||.:||..:|......:.:|.....||... .:.:..|:.|:.|:
Mosquito    67 VMPSGELQQKVMEENSIYSREIVIYSQIMPRIYELLRSIGDVSIISPLCL-TTANTPKQMLVFED 130

  Fly   610 LQPSGFKMVDRMIGMDLEHSKCTLKKLAQWHAAS-LKYKE--------LNGPYS--PKYNNGIFT 663
            :....|||:||.:|:||:|::..:.|||:.||.| :.|:.        :.|..|  ||
Mosquito   131 VSEQSFKMMDRRLGLDLDHARLVIVKLAKLHACSRIVYEAEPTLFDLMMEGCISDDPK------- 188

  Fly   664 EQTAPIFKGMFVNTKKSFIEEVSKFDGVDEYLHKMPEILDTYVDRILEDAKINEQAFNVLNHGDA 728
            :||...:....|......:::.:|....:..|.|:.::.|..:....:.....:..||||||.|.
Mosquito   189 KQTFLPYYRRCVGQVMRLVQQWNKDGRWNSILGKLDKLQDKIIPYGCDVYHRRDDCFNVLNHNDI 253

  Fly   729 WINNIMFQYESDGRVKETLLLDHQVTKYGNPAQDLYYFIMSSTQLDIKVDQFDYLIRWYHQNMKE 793
            |:||:|||:|....||:.||||:|::.||:|..||.:.:..|.|.:::......|::.||..::.
Mosquito   254 WVNNMMFQFEPGTGVKDVLLLDYQLSFYGSPGIDLNFLLYGSLQPEVRKLHLMELVQLYHTTLRG 318

  Fly   794 HAKLLNYNGFIPSLKELHAILIQHPIFAAGTVLTTLSMCLNKTTDDFTTDSFLGNEENGKSLREA 858
            ..:.|:|.|.||||.::|..:|:........|...:.:.:.:.::|...|..||..|..::.|..
Mosquito   319 TLEQLHYGGTIPSLPDIHVEIIRKGFHRVNAVFQQMPVAMMERSEDADMDLILGEGERSETCRRE 383

  Fly   859 MFSNERYRANIERVMPWINRRGLLD 883
            :|.|.||.:.:..::...:..|..|
Mosquito   384 LFDNPRYVSILPALLHEFDLAGYFD 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023	83/296 (28%)
AgaP_AGAP013201	XP_003436598.1	EcKinase	38..325	CDD:281023	83/296 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820