Protein Alignment CG6830 and AgaP_AGAP012971

DIOPT Version :9

• Sequence 1: NP_650103.1
• Gene: CG6830 / 41408
• FlyBaseID: FBgn0037934
• Length: 891
• Species: Drosophila melanogaster
• Sequence 2: XP_003436595.1
• Gene: AgaP_AGAP012971 / 11175866
• VectorBaseID: AGAP012971
• Length: 858
• Species: Anopheles gambiae
• Alignment Length: 886
• Identity: 267/886 - (30%)
• Similarity: 451/886 - (50%)
• Gaps: 90/886 - (10%)

  Fly    46 VPKWLNQTQFEELLAADVDQ----FSKIVGFRVKPAMAPGENYATLMLRISIDVEL--TDKSTKL 104
            ||:|:.:..|.:.:|..:.:    |: |....|:.|...|:|||:::.|:.:.|.|  ||.:...
Mosquito    11 VPEWMTKEYFVDAIAVKLGKPATDFT-ITDLDVRRATEAGDNYASILYRVRVSVRLHNTDGTPMD 74

  Fly   105 VSFMMKVPHDTPQMEQMMSMANFFTSENAAYTEILPKMEELYKAKG-LDIKFAPRAFKLDATKEP 168
            :|.::|........::|:.:.|.|..|.|.||::||::|:||...| ..:.|.||..|  .:.||
Mosquito    75 ISLIVKALPKLSLTDEMVKLMNLFPKEIAMYTDVLPRLEQLYHQAGRTSVHFGPRCLK--HSTEP 137

  Fly   169 KVANTVLMHDLGQNGFKNINRLECLNLEQTKFALTRLAQFHAAGATMVQVHGPYPDIFVNGVMGN 233
              .:.:::.||.:..|...||.:.|::|.|:..|.|:||||||...:....|||.::
Mosquito   138 --TDVIVLEDLRERQFTMANRRQGLDMEHTRLVLRRMAQFHAASVVLEDHRGPYGEL-------- 192

  Fly   234 NKEAIIAFMEGMLASFRTSFMANLDKFKNGE-EYREKL-----EKAL-AGLTMEFMKLGIVDP-- 289
                   |.|||   |.....|..::|:.|: ::.:|:     |||. ....|:...:.:.|.
Mosquito   193 -------FREGM---FTEKGRAMSEQFQKGQADFFQKIMRCWSEKAQHCASVMQHWGMDLFDSLI 247

  Fly   290 -------NEFNALNHGDCWMNNLLFKMNSSGDLEDMVFVDFQNPKYGSPAMDLLYFIISSVQIDY 347
                   ..||.|||||.|.||:||:.|....:.|::.:|:|...:.|||:||:||:.:||..|:
Mosquito   248 RVTRANRKGFNVLNHGDMWCNNILFQYNEDSTVNDILLIDYQLSFWASPAIDLIYFMFTSVNGDF 312

  Fly   348 KLSHFDFFIRHYQEALVKHLGILGFTGRKPSLRELHRTLIK---YGGWVLFPTISVLPLVLLDPT 409
            |||..::.:::|.|.||..|..||:||..|.|:|||..:|.   :|..:.|   |:||:.|::.|
Mosquito   313 KLSQMNYLVQYYHEHLVDSLKFLGYTGTVPLLKELHSDIISHHLFGYMICF---SILPICLMEKT 374

  Fly   410 QSATFDNFMSDSADGVSFRGSLYANKRCQEYIERILPWLDNRG---FLEVSTDPLPPELLAALKP 471
            ..|:.|..:...|.|.||:..:|.|......:|:::.:..:.|   .|::.|
Mosquito   375 DDASMDLMLDQGAAGESFKLKMYTNPVYVRQMEQLMEYFFDMGVHDLLQIGT------------- 426

  Fly   472 QQPQPENTD---QIPDWLNIDDFKEIILSAE----PNFEKILSST-SKLATKPGDNFASKLLKVE 528
            |:|...:.|   ::|.||: .:|.|.|:.|:    |..::.:.|. :|.|.|.||::|:.|..|:
Mosquito   427 QRPARIDCDPSLELPLWLD-REFVEHIVDAKFGIAPEDKRTVRSVYTKNAAKKGDSYAAALYSVK 490

  Fly   529 IEAQLKDNSV-KTFSYILKVHSDNDAINFS-DFNLFPKEIEVYSTYVPAFERFYKDVGLPVTFSP 591
            :|...||..| :|.|.|:|........::| |..::.:|:.:|...:||||..|:..|:.|...|
Mosquito   491 VELLWKDAGVEETLSLIVKAPPKGITASYSLDKEVYVRELYLYEHLIPAFEALYRSKGVSVKLGP 555

  Fly   592 KSFRLSKDVSKEYLLLENLQPSGFKMVDRMIGMDLEHSKCTLKKLAQWHAASLKYKELNGPYSPK 656
            :.::....:..|.::||:|..||::|.:|...:|..|.:..|..|||:||||..|.|     |.|
Mosquito   556 RYYKPRVGLPVEVIVLEDLTISGYRMANRQDCLDQAHLEVALNHLAQFHAASAVYSE-----SGK 615

  Fly   657 YNNGIFT-----EQTAPIFKGMFVNTKKSFIEEVSKFDGVDEYLHKMPEILDTYVDRILEDAKIN 716
            ....|.|     .|.|.....||..:..|....:.::|...|::..:..:.......:::...:|
Mosquito   616 TLPAILTASSADRQMAAKTDHMFAPSLDSLFGYMREWDFAGEFVDDLETVAKQIYQLLVDTWTLN 680

  Fly   717 EQAFNVLNHGDAWINNIMFQY-ESDGRVKETLLLDHQVTKYGNPAQDLYYFIMSSTQLDIKVDQF 780
            ...||||||||||:||::|.| :.||.|....|:|.|...:|:|..||.:|:.||.:.|:|:.:.
Mosquito   681 PDGFNVLNHGDAWLNNMLFAYNDYDGSVDRMALIDFQFPSWGSPVFDLIHFLFSSARADLKLSKQ 745

  Fly   781 DYLIRWYHQNMKEHAKLLNYNGFIPSLKELHAILIQHPIFAAGTVLTTLSMCLNKTTDDFTTDSF 845
            .|.:|:|.:.:..:..||.|...:|:|::||.........|..||:..|...|...|||.:.::.
Mosquito   746 AYFLRYYQERLVHNLVLLGYGKPLPTLRQLHLDFNDRLTAAIKTVVIDLPYVLVDDTDDASQEAA 810

  Fly   846 LGNEENGKSLREAMFSNERYRANIERVMPWINRRGLLDNFA 886
            :...|.|:..::.:|.||||:..::.::|:...||||...|
Mosquito   811 IVQTEVGQRFQKLLFDNERYKEQLKDLLPYFRSRGLLTPLA 851

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023	98/310 (32%)
		EcKinase	516..800	CDD:281023	91/291 (31%)
AgaP_AGAP012971	XP_003436595.1	EcKinase	49..337	CDD:281023	98/309 (32%)
		EcKinase	478..765	CDD:281023	91/291 (31%)
		Adenylation_DNA_ligase_like	<776..811	CDD:299865	9/34 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	207	1.000	Domainoid score	I6156
eggNOG	1	0.900	-	-		E1_2AMXB
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H138253
Inparanoid	1	1.050	403	1.000	Inparanoid score	I3931
OMA	1	1.010	-	-		QHG27462
OrthoDB	1	1.010	-	-		D101022at50557
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	1	1.000	-	-		mtm9677
Panther	1	1.100	-	-	O	PTHR11012
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11768
TreeFam	1	0.960	-	-
	13	12.940