DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6830 and AgaP_AGAP013194

DIOPT Version :9

Sequence 1:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	XP_003436597.1	Gene:	AgaP_AGAP013194 / 11175655	VectorBaseID:	AGAP013194	Length:	404	Species:	Anopheles gambiae

Alignment Length:	422	Identity:	119/422 - (28%)
Similarity:	207/422 - (49%)	Gaps:	48/422 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   485 WLNIDDFKEII---LSAE-------PNFEKILSSTSKLATKPGDNFASKLLKVEIEAQLKDNSVK 539
            |...:.||:.|   ||.|       .:|| :..:..|.|     .:.|.:.:|.||.:....:.|
Mosquito     6 WKTAEFFKDAIVRDLSLECTDSFTITSFE-VGKANEKTA-----GYMSNIYRVLIELKFDKGTAK 64

  Fly   540 --TFSYILKVHSDNDAINFSD-----FNLFPKEIEVYSTYVPAFERFYKDVGLPVTFSPKSFRLS 597
              :.|||:|..:|.   .|..     .::||||.|||...:|||||..::....|.|.||..:.:
Mosquito    65 PTSLSYIVKEKTDT---AFGSGLVELLSVFPKESEVYEKLLPAFERLVQNEEETVRFGPKVLKTT 126

  Fly   598 KDVSKEYLLLENLQPSGFKMVDRMIGMDLEHSKCTLKKLAQWHAASLKYKELNGPYSPKYNNGIF 662
            .: ....::||:|..|.|:|.::..|:.:...|..|:|||::||||:.|.|.||.:|..:..|:.
Mosquito   127 TN-PDTVIVLEDLSRSQFRMREKSFGLSVTDVKRILEKLAKFHAASVLYVEKNGAFSDLFAEGVI 190

  Fly   663 TEQTAPIFKGMFVNTKKSFIEEVSKFDGVDEYLHKMPEILDTYVDRILEDAKINEQAFNVLNHGD 727
            :|:|....:|.:.:...:|::.:...:...|||..:.:.....:....:..:::.....||||||
Mosquito   191 SERTIDALRGHYESLYSAFVQSLRDRNMAPEYLQPLIKFDGQLLRECCKAQQVHHSELKVLNHGD 255

  Fly   728 AWINNIMFQYESDGRVKETLLLDHQVTKYGNPAQD-LYYFIMSSTQLDIKVDQFDYLIRWYHQNM 791
            .|.||:||..|      :...||.|...||:||.| ||:|..|:|:|  ..|..:.|:::||:::
Mosquito   256 LWPNNVMFGTE------DLRFLDFQTASYGSPAADLLYFFATSATEL--MCDSLEELLQYYHEHL 312

  Fly   792 KEHAKLLNYNGFIPSLKEL------HAILIQHPIFAAGTVLTTLSMCLNKTTDDFTTDSFLGNEE 850
            .:..:.|.|...||...||      .::|:..|:..|      |::.::..|:....:.....:.
Mosquito   313 VKTLQQLQYCKSIPMYTELLDQMRRRSVLLLPPLSEA------LAITMSGLTEPSDMEMITSEQP 371

  Fly   851 NGKSLREAMFSNERYRANIERVMPWINRRGLL 882
            .|.:||:.:::|..|.|.|:|::|.:....||
Mosquito   372 EGVALRKLVYNNPAYVALIDRLLPKLYELRLL 403

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023	87/291 (30%)
AgaP_AGAP013194	XP_003436597.1	PKc_like	44..321	CDD:304357	87/288 (30%)
AgaP_AGAP013194	XP_003436597.1	APH	<208..310	CDD:279908	33/109 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11012
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.880