DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6830 and AgaP_AGAP013239

DIOPT Version :9

Sequence 1:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	XP_003435873.1	Gene:	AgaP_AGAP013239 / 11175591	VectorBaseID:	AGAP013239	Length:	425	Species:	Anopheles gambiae

Alignment Length:	450	Identity:	107/450 - (23%)
Similarity:	192/450 - (42%)	Gaps:	88/450 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   463 PELLAALKPQQPQPENTDQIPDWLNIDDFKEIILSAEPNF-EKILSSTSKLATKPGDNFASKLLK 526
            |||||.            .:|::: ....||:  :.|..| |.:....|:..:..||.|..:|||
Mosquito     2 PELLAT------------SLPEYI-AAGLKEV--AQEQRFTEGLYRLESESGSNMGDGFVGQLLK 51

  Fly   527 VEIEAQLKDNSVKTFSYILKVHSDNDAINFSDFNLFPKEIEVYSTYVPAFERFYKDVGLPVTFS- 590
            |.|....::..|     :.|:..:::.......:||.:|.|.|...:|...:|..:..|.....
Mosquito    52 VFIREADRELVV-----LCKLLPESEMRKQQGISLFDRETEAYMQILPLLTKFQDEKALAKHLPR 111

  Fly   591 ----PKSF--RLSKDVSKEYLLLENLQPSGFKMVDRMIGMDLEHSKCTLKKLAQWHAASLKYKEL 649
                |:.:  :.:.|..:..:::|:|:...::|.|:...:|.||::..:..|.:.||.|...|:
Mosquito   112 FDNVPRCYYAKTTLDKMESVIIMEDLRLQAYRMWDKANPVDFEHARLLMVTLGRLHALSFAMKD- 175

  Fly   650 NGPYSPKYNNGIFTEQTA---PIFKGMFVNTKKSF-----------IEEVSKFDGVDEYLHKMPE 700
               ..|:.    |.:..|   |:.|.:.::..|.|           ||.:.:.|....  .|:.:
Mosquito   176 ---QQPEE----FAKCRAFEDPMGKMLELDPTKGFEVMMAGMCRRAIETLDQHDNFRR--EKLKQ 231

  Fly   701 ILDTYVDRIL--EDAKINEQAFNVLNHGDAWINNIMFQYESDGRVKETL-LLDHQVTKYGNPAQD 762
            |.|..|..|:  .|.|..| .:.::.|||.|.||:||||..|.:....: |:|.|:::||:|..|
Mosquito   232 IQDRCVQEIVACTDGKAAE-PYAIVGHGDCWSNNMMFQYAEDNKTPSNIKLIDWQLSRYGSPVLD 295

  Fly   763 LYYFIMSSTQLDIKVDQFDYLIRWYHQNMKEHAKLLNYNGFIPSLKELHAILIQHPIFA------ 821
            |.|||.:.|..:::...:..|:..|:.::.||  |.|..|.:..         |:|..|
Mosquito   296 LVYFIFNCTDEEMRSHSYQRLLSIYYHSLSEH--LHNLGGDVER---------QYPRIAFREQLK 349

  Fly   822 ----AGTVLTTLSMCLNKTTDDFTTDS------FLGNEENGKSLREAMFSNE-----RYR 866
                .|.|::.:.:.:..|.:|...|:      |:.:..||.:..|..:...     |||
Mosquito   350 KFGRYGLVMSMMVLPIICTPNDELPDTDTAMEGFMNDMTNGNTNAELAYGTTEKAAIRYR 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023	78/307 (25%)
AgaP_AGAP013239	XP_003435873.1	EcKinase	42..332	CDD:281023	79/307 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810