DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6830 and AgaP_AGAP013124

DIOPT Version :9

Sequence 1:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	XP_003435871.1	Gene:	AgaP_AGAP013124 / 11175451	VectorBaseID:	AGAP013124	Length:	622	Species:	Anopheles gambiae

Alignment Length:	393	Identity:	89/393 - (22%)
Similarity:	171/393 - (43%)	Gaps:	58/393 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   512 LATKPGDNFASKLLKVEI-EAQLKDNSVKTFSYILKVHSDNDA--INFSDFNLFPKEIEVYSTYV 573
            :.:..||.|..::.|..: |.:.::      .|:.|:...|:|  ..|....:|.:|...|.:.:
Mosquito   243 VGSNKGDGFVGQMFKAFLQEGERRE------VYLCKIPPLNEARRQQFQSMTIFSRETLAYKSLL 301

  Fly   574 PAFERFYKDVGLPVT---FS-PKSFRLSKDVSKE--YLLLENLQPSGFKMVDRMIGMDLEHSKCT 632
            |....:.::.|:...   |: ||.:....|.:.|  .:::|:|:...::|.::::.::.||::.|
Mosquito   302 PLIFTYQEEKGISREDGFFNVPKCYYAECDETTEQSVIIMEDLRLKDYRMWNKLVPVNYEHARLT 366

  Fly   633 LKKLAQWHAASLKYK----------ELNGPYSPKYNNGIFTEQTAPIFKGMFV---NTKKSFIE- 683
            :::|.:.||.||..|          ::..|..      :...:.:| |:.|.:   ...|..:|
Mosquito   367 MQQLGRLHAVSLAMKRDRPADFEQFKVPDPLE------VMMPEGSP-FEAMMIKMLTDAKETLEP 424

  Fly   684 -EVSKFDGVDEYLHKMPEILDTYVDRILEDAKINEQAFNVLNHGDAWINNIMFQYESDGRVKETL 747
             |..:...:.:.:..|.:.:.|..|..|      .:.:.||.|||.|:||.||.|: :|..:..:
Mosquito   425 HETKERTKMQKLIDNMRQEMKTCTDGAL------AEPYAVLGHGDCWVNNFMFHYK-NGAPEHVI 482

  Fly   748 LLDHQVTKYGNPAQDLYYFIMSSTQLDIKVDQFDYLIRWYHQNMKEHAKLLNYN--------GFI 804
            |||.|:|:|.:|..||.|||...|..:.:...:|.::..|:.:::...:.|.:|        ..:
Mosquito   483 LLDWQITRYVSPVTDLSYFIFCCTDGEFRRRHYDEMMSIYYNSLEALLEKLGHNPQEVFPRTALM 547

  Fly   805 PSLKELHAILIQHPIFAAGTVLTTLSMCLNKTTDDFTTDSFLGNEENGKSLREAMFSNERYRANI 869
            ..|:......|...||....:.|.     |:...|....:....|.|...| .||..|...||..
Mosquito   548 RQLRRFGRFGILMAIFLVPMLCTR-----NEDLPDMDEAAEKYRETNEMDL-NAMTLNANQRAYR 606

  Fly   870 ERV 872
            ||:
Mosquito   607 ERM 609

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023	71/307 (23%)
AgaP_AGAP013124	XP_003435871.1	EcKinase	247..535	CDD:281023	71/307 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810