Protein Alignment Ho and HMX1

DIOPT Version :9

• Sequence 1: NP_524321.1
• Gene: Ho / 41407
• FlyBaseID: FBgn0037933
• Length: 296
• Species: Drosophila melanogaster
• Sequence 2: NP_013306.2
• Gene: HMX1 / 850902
• SGDID: S000004195
• Length: 317
• Species: Saccharomyces cerevisiae
• Alignment Length: 306
• Identity: 57/306 - (18%)
• Similarity: 117/306 - (38%)
• Gaps: 76/306 - (24%)

  Fly     1 MSASEETIADSQVSENVEDVEFVDMAFTKELRKATKDVHNLTDVLVNAKIALALSDDEVWYDGLL 65
            |..|..||..|..     ||.    |....:...|:|.||..:..:..|:|:|:....::..|:|
Yeast     1 MEDSSNTIIPSPT-----DVG----ALANRINFQTRDAHNKINTFMGIKMAIAMRHGFIYRQGIL 56

  Fly    66 AFYELYKFFETHLPERLLP-------------------KEFHRTAAFERDFAYFYGSDWRK---- 107
            |:|.::...|..: :|||.                   ::|.|:....:|....|.:.::.
Yeast    57 AYYYVFDAIEQEI-DRLLNDPVTEEELQTSTILKQFWLEDFRRSTQIYKDLKLLYSNTFKSTESL 120

  Fly   108 -----DYEIRPAVQKYLEHLEKIAAQNELLLFAYSYQMYMALMSGGQMLQKKRMIARKMWIFSKN 167
                 .::..|.:|:::.::.:...:....:.:|.:.:|:||.:||::::..  :.|::.:|...
Yeast   121 NEFLATFQKPPLLQQFINNIHENIHKEPCTILSYCHVLYLALFAGGKLIRSN--LYRRLGLFPNF 183

  Fly   168 DDEEQQKQADKEAELATARAADGSVDKDDLEARPMPAQVTICPPGCEATYFPEKISVLKAKLRRV 232
            :...|::...|.....|.         .||.                    |.:.:.||.:.::
Yeast   184 EKLSQKELVKKGTNFFTF---------SDLG--------------------PTEETRLKWEYKK- 218

  Fly   233 FNNHYGAFDDDLRAA----FIEESRNVFRLNIEVVRTIKGVNRANL 274
              |:..|...:|..|    .|..:..:|..|..:|..|..:||..|
Yeast   219 --NYELATRTELTEAQKLQIISVAEGIFDWNFNIVAEIGELNRREL 262

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ho	NP_524321.1	Heme_oxygenase	25..265	CDD:279470	46/271 (17%)
HMX1	NP_013306.2	COG5398	45..289	CDD:227685	42/253 (17%)
		kinked helix	149..176	CDD:350856	6/28 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346550
Domainoid	1	1.000	50	1.000	Domainoid score	I2910
eggNOG	1	0.900	-	-		E1_COG5398
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	50	1.000	Inparanoid score	I1838
Isobase	1	0.950	-	0	Normalized mean entropy	S5532
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002659
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_104451
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2150
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.630