Protein Alignment Ho and Hmox2

DIOPT Version :9

• Sequence 1: NP_524321.1
• Gene: Ho / 41407
• FlyBaseID: FBgn0037933
• Length: 296
• Species: Drosophila melanogaster
• Sequence 2: NP_001264002.1
• Gene: Hmox2 / 79239
• RGDID: 67402
• Length: 315
• Species: Rattus norvegicus
• Alignment Length: 372
• Identity: 81/372 - (21%)
• Similarity: 123/372 - (33%)
• Gaps: 150/372 - (40%)

  Fly     1 MSASEETIADSQVSENVEDVEFVDMAFTKE-----------LRKATKDVHN-------LTDVLV- 46
            ||:..||      ||.|::.|....|..||           |::.||:.|:       :.|.|.
  Rat     1 MSSEVET------SEGVDESENNSTAPEKENHTKMADLSELLKEGTKEAHDRAENTQFVKDFLKG 59

  Fly    47 NAKIALALSDDEVWYDGLLAFYELYKFFETHLPER---------LLPKEFHRTAAFERDFAYFYG 102
            |.|       .|::.....|.|..|...|..:...         ..|.|.||..|..:|..||:|
  Rat    60 NIK-------KELFKLATTALYFTYSALEEEMDRNKDHPAFAPLYFPTELHRKEALIKDMEYFFG 117

  Fly   103 SDWRKDYEIRPAVQKYLEHLEKIAAQNELLLFAYSYQMYMALMSGGQMLQKKRMIARKM------ 161
            .:|.:..:...|.|||::.:..:......||.|::|..||..:||||:|:|....|.|:
  Rat   118 ENWEEQVKCSEAAQKYVDRIHYVGQNEPELLVAHAYTRYMGDLSGGQVLKKVAQRALKLPSTGEG 182

  Fly   162 ---WIFSKNDDEEQQKQADKEAELATARAADGSVDKDDLEARPMPAQVTICPPGCEATYFPEKIS 223
               ::|...|:.:|.||..:    |...|.|.|
  Rat   183 TQFYLFEHVDNAQQFKQFYR----ARMNALDLS-------------------------------- 211

  Fly   224 VLKAKLRRVFNNHYGAFDDDLRAAFIEESRNVFRLNIEV-------------------------- 262
             :|.|.|                 .:||:...|..|:::
  Rat   212 -MKTKER-----------------IVEEANKAFEYNMQIFSELDQAGSMLTKETLEDGLPVHDGK 258

  Fly   263 --VR------------TIKGVN------RANLRKLALALIFVSSIVV 289
              ||            |:.|.|      .|.|||.:|.||..:|:.:
  Rat   259 GDVRKCPFYAAQPDKGTLGGSNCPFRTAMAVLRKPSLQLILAASVAL 305

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ho	NP_524321.1	Heme_oxygenase	25..265	CDD:279470	62/316 (20%)
Hmox2	NP_001264002.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..29		11/33 (33%)
		Heme_oxygenase	30..235	CDD:395895	57/265 (22%)
		kinked helix	146..173	CDD:350856	12/26 (46%)
		HRM 1	263..268		0/4 (0%)
		HRM 2	280..285		1/4 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353865
Domainoid	1	1.000	70	1.000	Domainoid score	I9310
eggNOG	1	0.900	-	-		E1_COG5398
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	66	1.000	Inparanoid score	I5256
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1424194at2759
OrthoFinder	1	1.000	-	-		FOG0002659
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_104451
Panther	1	1.100	-	-	O	PTHR10720
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.760