Protein Alignment CG18476 and ZNF484

DIOPT Version :10

• Sequence 1: NP_731615.1
• Gene: CG18476 / 41404
• FlyBaseID: FBgn0037931
• Length: 936
• Species: Drosophila melanogaster
• Sequence 2: XP_011517375.1
• Gene: ZNF484 / 83744
• HGNCID: 23385
• Length: 884
• Species: Homo sapiens
• Alignment Length: 503
• Identity: 97/503 - (19%)
• Similarity: 170/503 - (33%)
• Gaps: 153/503 - (30%)

  Fly     5 TPEKPEEIIDATGTSDTAEKIEVVISKEE-PAEQKNE---VEEPDYAQVPAESEDDAAQELAPTD 65
            |.|.|....|:|||.....:.::.::|.| ..|.|:.   |::|:||.|...|       :...:
Human   509 TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGS-------MVSFE 566

  Fly    66 SAIQVVHVL-----------EAPQKAELVTIPLAHSEAEDHKLADADRDQEEELVFNEERRKTVT 119
            ..::..|.|           |.|.. |..|:.      :|| |..||        .:::...|.|
Human   567 CKVKHDHTLSLTVLWLKDNRELPSD-ERFTVD------KDH-LVVAD--------VSDDDSGTYT 615

  Fly   120 MDDNASLRSASITFDANRDEQDLLNESFASNPTDETVLMQKTKDEMDATSERPRSPLDLPPPPAS 184
            ...|.:|.|.|.:        .:|:.....||..:..|    .|::|.:.:...:|.|....|.:
Human   616 CVANTTLDSVSAS--------AVLSVVDVPNPPFDLEL----TDQLDKSVQLSWTPGDDNNSPIT 668

  Fly   185 --VVLHPSAPPPPPPPLSSTEVVGNTTTTTTTHYAPKTWNDPSITTAPKIPVS-----LLSGAQP 242
              ::.:..|...|......|||.|..||.             .:..:|.:..|     :.|..:.
Human   669 KFIIEYEDAMHKPGLWHHQTEVSGTQTTA-------------QLKLSPYVNYSFRVMAVNSIGKS 720

  Fly   243 LPSVLTQRTTTSSYSAPNYSASSMSGVPSDVAPPPPLPIP----NQSSSSAASYQHHHA------ 297
            |||..:::..|.: |.|:.:.:::.|:.|:   |..|.|.    |...|:....|:..:
Human   721 LPSEASEQYLTKA-SEPDKNPTAVEGLGSE---PDNLVITWKPLNGFESNGPGLQYKVSWRQKDG 781

  Fly   298 ---------SSISKSISSSRED----LLSEHATSRSTVREIPV----HRA---PSTAPS------ 336
                     :::||.|.|....    |:...|.:.......|.    |..   |..||.
Human   782 DDEWTSVVVANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNV 846

  Fly   337 -HSSVFEYHMMPTTTST---------YHHVETPSDEYYRREVMTRTIIT---------------- 375
             :|::.|.|..|....:         .::.:|.|.....|..:.:.|:|
Human   847 VNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPF 911

  Fly   376 -----------------RSTEALSQTPLGRPASPLDRYLPYPTTTTTT 406
                             .|.:.:..||.|.|::|....:..||..:.|
Human   912 SHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLT 959

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18476	NP_731615.1	C2H2 Zn finger	206..227	CDD:275368	3/20 (15%)
		C2H2 Zn finger	236..256	CDD:275368	5/19 (26%)
		C2H2 Zn finger	401..422	CDD:275368	2/6 (33%)
		C2H2 Zn finger	431..447	CDD:275368
		C2H2 Zn finger	461..481	CDD:275368
		C2H2 Zn finger	490..511	CDD:275368
		C2H2 Zn finger	520..540	CDD:275368
		C2H2 Zn finger	638..659	CDD:275368
		C2H2 Zn finger	668..690	CDD:275368
		C2H2 Zn finger	698..715	CDD:275368
		C2H2 Zn finger	753..774	CDD:275368
		C2H2 Zn finger	790..810	CDD:275368
		COG5048	814..>886	CDD:227381
		C2H2 Zn finger	818..838	CDD:275368
		C2H2 Zn finger	846..866	CDD:275368
		C2H2 Zn finger	874..894	CDD:275368
		C2H2 Zn finger	902..924	CDD:275368
ZNF484	XP_011517375.1	KRAB	25..84	CDD:214630
		C2H2 Zn finger	313..333	CDD:275368
		C2H2 Zn finger	362..382	CDD:275368
		C2H2 Zn finger	391..410	CDD:275368
		zf-H2C2_2	402..427	CDD:463886
		C2H2 Zn finger	418..438	CDD:275368
		COG5048	442..843	CDD:227381	79/385 (21%)
		C2H2 Zn finger	446..466	CDD:275368
		C2H2 Zn finger	474..494	CDD:275368
		C2H2 Zn finger	502..522	CDD:275368	5/12 (42%)
		C2H2 Zn finger	530..550	CDD:275368	4/19 (21%)
		C2H2 Zn finger	558..578	CDD:275368	3/26 (12%)
		C2H2 Zn finger	586..606	CDD:275368	9/35 (26%)
		C2H2 Zn finger	614..634	CDD:275368	6/27 (22%)
		C2H2 Zn finger	642..662	CDD:275368	4/23 (17%)
		C2H2 Zn finger	670..690	CDD:275368	3/19 (16%)
		C2H2 Zn finger	698..718	CDD:275368	3/19 (16%)
		C2H2 Zn finger	726..746	CDD:275368	3/20 (15%)
		C2H2 Zn finger	754..774	CDD:275368	4/19 (21%)
		C2H2 Zn finger	782..802	CDD:275368	4/19 (21%)
		C2H2 Zn finger	810..830	CDD:275368	2/19 (11%)