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Protein Alignment CG18476 and ZFP62

DIOPT Version :9

Sequence 1:	NP_731615.1	Gene:	CG18476 / 41404	FlyBaseID:	FBgn0037931	Length:	936	Species:	Drosophila melanogaster
Sequence 2:	NP_001166109.1	Gene:	ZFP62 / 643836	HGNCID:	23241	Length:	900	Species:	Homo sapiens

Alignment Length:	872	Identity:	221/872 - (25%)
Similarity:	334/872 - (38%)	Gaps:	215/872 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 MKHLKNGAAPTSTDCLQEAPMELCAEQHVEV-----KLETEDEDCGENDVTITC-------SELP 135
            |.|||     |||:  .|.|    .|::..|     |....::...|:.|..||       ::..
Human     1 MSHLK-----TSTE--DEEP----TEEYENVGNAASKWPKVEDPMPESKVGDTCVWDSKVENQQK 54

  Fly   136 EPDETDMESKKS-----VDPLTMIETVKLEMEPRSVEKPAYDDP-----------TSDFEDEDSL 184
            :|.|..|:..||     :........:|.|.|..:.||..:..|           ....|....:
Human    55 KPVENRMKEDKSSIREAISKAKSTANIKTEQEGEASEKSLHLSPQHITHQTMPIGQRGSEQGKRV 119

  Fly   185 DNL--PLYNRIQKWKTGRKSVYKCHDCPRSFKRFDFLKRHEMRVHKPETRLYDCSLCIRKFSRSE 247
            :|:  ..|..:|:.....|.::||.:|.:|||....|.:|:: :|..|.| |:|..|...|..|.
Human   120 ENINGTSYPSLQQKTNAVKKLHKCDECGKSFKYNSRLVQHKI-MHTGEKR-YECDDCGGTFRSSS 182

  Fly   248 ALEAHLKIHRNSKRSANISEHKKAKAVDLNLCKPHGYKLIECMICQSQYNKIADLRRHLEEHPDI 312
            :|..|.:||.                         |.|..:|..|...|...:.|..|...|
Human   183 SLRVHKRIHT-------------------------GEKPYKCEECGKAYMSYSSLINHKSTH--- 219

  Fly   313 VSLCGRPNMEPHELAELF-YPDSKDLSEEQLINLIRKDLAAGIYQRFYSITNQSGYEMDLDSSET 376
               .|..|.:..|..:.| |  |..|.:.:.|:...|....|...:  :..|.||..:
Human   220 ---SGEKNCKCDECGKSFNY--SSVLDQHKRIHTGEKPYECGECGK--AFRNSSGLRV------- 270

  Fly   377 DSDLDGDHDDQHKRRKKSRKATYSCELCQQKFPRKYQLYDHQRQSHSWSDAPHVCGRCDGRFVSL 441
                       |||.....| .|.|::|.:.|.....|..|:| .|: .:.|:.|..|...|::.
Human   271 -----------HKRIHTGEK-PYECDICGKTFSNSSGLRVHKR-IHT-GEKPYECDECGKAFITC 321

  Fly   442 QLLRHHNESQCRNAQKRFLCHKCPLRFRWKHNLKTHFREHRITN---QTFECSECKRVFDKKKSL 503
            :.|.:|  .......|.:.|.:|...|    |..:...:|::.:   :.:||.||.:.|.....|
Human   322 RTLLNH--KSIHFGDKPYKCDECEKSF----NYSSLLIQHKVIHTGEKPYECDECGKAFRNSSGL 380

  Fly   504 TVHLLSVHAEESKLIPCQWCSRKFYRHDYLVKHLKRH-GLKEHDIPLAETLIAATSRPNGAKRIT 567
            .|| ..:|..| |...|..|.:.|.....|..|...| |.|.|:
Human   381 IVH-KRIHTGE-KPYKCDVCGKAFSYSSGLAVHKSIHPGKKAHE--------------------- 422

  Fly   568 CRMCNLHFERIVDLRAHIQLELKLSLSLHQSYDSPHNYSITNESGFELQLEDSETEDEMQPGVGS 632
            |:.|...|                      ||:|           ..||.....|        |.
Human   423 CKECGKSF----------------------SYNS-----------LLLQHRTIHT--------GE 446

  Fly   633 RPVYICELCSVQCKRKFEMIQHQRTMHRFDKMPHECDDCIFKCVSKSIMDHHRQGQCSSTEKKHA 697
            || |:|::|....:....:..|:| :|..:| |::||.|....:|:|.:.:|:.....  ||.:.
Human   447 RP-YVCDVCGKTFRNNAGLKVHRR-LHTGEK-PYKCDVCGKAYISRSSLKNHKGIHLG--EKPYK 506

  Fly   698 CGKCSYKFMWPENLEQHILLQHSKSSVSNPTGDRHTQGTGDLEKDATEDGIPLLQCPHCDRTYQM 762
            |..|...|.:...||||..: |::   ..|.|                       |..|.:.::.
Human   507 CSYCEKSFNYSSALEQHKRI-HTR---EKPFG-----------------------CDECGKAFRN 544

  Fly   763 KSRLNNHIRDVHINGDRKRKEAIKRFLCSLCGMETRSAAALVTHMRRHTGEKPFKCDLCEMAFPR 827
            .|.|..|.| :| .|:|..|       |..||....|.::|:.|...|.||||||||.||.||..
Human   545 NSGLKVHKR-IH-TGERPYK-------CEECGKAYISLSSLINHKSVHPGEKPFKCDECEKAFIT 600

  Fly   828 HSELASHRRMHTGEKPFHCTVCGKDFARSDKLKRHMLTHSGLKPHKCTYCEKSYRQAKDLKLHLQ 892
            :..|.:|:::|.||||:.|.||.|.|..:..|.:|...|:..||::|..|||.:|....||:|.:
Human   601 YRTLTNHKKVHLGEKPYKCDVCEKSFNYTSLLSQHRRVHTREKPYECDRCEKVFRNNSSLKVHKR 665

  Fly   893 QHTGECPFVCGTCGERFIQSSTLEKHR 919
            .||||.|:.|..||:.:|..|:|..|:
Human   666 IHTGERPYECDVCGKAYISHSSLINHK 692

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.