DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18476 and ikzf5

DIOPT Version :9

Sequence 1:	NP_731615.1	Gene:	CG18476 / 41404	FlyBaseID:	FBgn0037931	Length:	936	Species:	Drosophila melanogaster
Sequence 2:	NP_991164.1	Gene:	ikzf5 / 402893	ZFINID:	ZDB-GENE-040801-209	Length:	419	Species:	Danio rerio

Alignment Length:	197	Identity:	55/197 - (27%)
Similarity:	85/197 - (43%)	Gaps:	29/197 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   738 DLEKDATEDGIPLLQCPHCDRTYQMKSRLNNHIRDVHINGDRKRKEAIKRFLCSLCGMETRSAAA 802
            ||:.:..::|   |:.|..|.:.:..|       .:.::|..:..:.  :..|..|...||..|.
Zfish    41 DLQGELAQNG---LEHPAVDMSLEDSS-------GMLVDGFERTYDG--KLKCRYCNYATRGTAR 93

  Fly   803 LVTHMRRHTGEKPFKCDLCEMAFPRHSELASHRRMHTGEKPFHCTVCGKDFARSDK--LKRHMLT 865
            |:.|:|.||||||.:|.||..|......|.:|.|.||||||:.|.:|  .|..||:  |..|...
Zfish    94 LIEHIRIHTGEKPHRCHLCPFASAYERHLEAHMRSHTGEKPYKCELC--SFRCSDRSNLSHHRRR 156

  Fly   866 HSGLKPHKCTYCEKSYRQAKDLKLHLQQHTGECPFVCGTCGERFI-----QSSTLEKHRLMRRHF 925
            ...|.|.|......|:|:...:   ||:......:     |.|.:     .|..|:|....::|.
Zfish   157 RHKLLPMKGARSALSHRKMLSV---LQKRGNSLSY-----GRRLLINLSPPSMVLQKPSSEQQHL 213

  Fly   926 DE 927
            .:
Zfish   214 GD 215

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18476	NP_731615.1	zf-AD	6..84	CDD:285071
		C2H2 Zn finger	206..227	CDD:275368
		C2H2 Zn finger	236..256	CDD:275368
		C2H2 Zn finger	401..422	CDD:275368
		C2H2 Zn finger	431..447	CDD:275368
		C2H2 Zn finger	461..481	CDD:275368
		C2H2 Zn finger	490..511	CDD:275368
		C2H2 Zn finger	520..540	CDD:275368
		C2H2 Zn finger	638..659	CDD:275368
		C2H2 Zn finger	668..690	CDD:275368
		C2H2 Zn finger	698..715	CDD:275368
		C2H2 Zn finger	753..774	CDD:275368	3/20 (15%)
		C2H2 Zn finger	790..810	CDD:275368	8/19 (42%)
		zf-H2C2_2	802..825	CDD:290200	12/22 (55%)
		COG5048	814..>886	CDD:227381	27/73 (37%)
		C2H2 Zn finger	818..838	CDD:275368	7/19 (37%)
		zf-H2C2_2	830..855	CDD:290200	12/24 (50%)
		C2H2 Zn finger	846..866	CDD:275368	7/21 (33%)
		zf-H2C2_2	859..883	CDD:290200	6/23 (26%)
		C2H2 Zn finger	874..894	CDD:275368	4/19 (21%)
		C2H2 Zn finger	902..924	CDD:275368	5/26 (19%)
ikzf5	NP_991164.1	C2H2 Zn finger	81..101	CDD:275368	8/19 (42%)
		zf-H2C2_2	94..118	CDD:290200	13/23 (57%)
		COG5048	105..>163	CDD:227381	23/59 (39%)
		C2H2 Zn finger	109..129	CDD:275368	7/19 (37%)
		zf-H2C2_2	121..145	CDD:290200	12/25 (48%)
		C2H2 Zn finger	137..155	CDD:275368	7/19 (37%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	203..255		3/13 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	310..360
		C2H2 Zn finger	368..388	CDD:275370
		C2H2 Zn finger	396..412	CDD:275370
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000