DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18476 and Ikzf5

DIOPT Version :9

Sequence 1:	NP_731615.1	Gene:	CG18476 / 41404	FlyBaseID:	FBgn0037931	Length:	936	Species:	Drosophila melanogaster
Sequence 2:	NP_001101025.1	Gene:	Ikzf5 / 309031	RGDID:	1310965	Length:	419	Species:	Rattus norvegicus

Alignment Length:	182	Identity:	57/182 - (31%)
Similarity:	80/182 - (43%)	Gaps:	41/182 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   708 PENLE-----QHILLQ--HSKSSVS-NPTGDRHT---QGTGDLEKDATEDGIPLLQCPHCDRTYQ 761
            ||.|:     |..|.|  |..:.:| :.:||:..   ||.|   .|..::|   |..|..:.:..
  Rat     6 PEPLDFVKDFQEYLTQQTHHVNMISGSVSGDKEAETLQGAG---TDGDQNG---LDHPSVEVSLD 64

  Fly   762 MKSRLNNHIRDVHING-----DRKRKEAIKRFLCSLCGMETRSAAALVTHMRRHTGEKPFKCDLC 821
            ..|       .:.::|     |.|.|       |..|...::..|.|:.|:|.||||||.:|.||
  Rat    65 ENS-------GMLVDGFERTFDGKLK-------CRYCNYASKGTARLIEHIRIHTGEKPHRCHLC 115

  Fly   822 EMAFPRHSELASHRRMHTGEKPFHCTVCGKDFARSDKLKRHMLTHSGLKPHK 873
            ..|......|.:|.|.||||||:.|.:|  .|..||   |..|:|...:.||
  Rat   116 PFASAYERHLEAHMRSHTGEKPYKCELC--SFRCSD---RSNLSHHRRRKHK 162

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18476	NP_731615.1	zf-AD	6..84	CDD:285071
		C2H2 Zn finger	206..227	CDD:275368
		C2H2 Zn finger	236..256	CDD:275368
		C2H2 Zn finger	401..422	CDD:275368
		C2H2 Zn finger	431..447	CDD:275368
		C2H2 Zn finger	461..481	CDD:275368
		C2H2 Zn finger	490..511	CDD:275368
		C2H2 Zn finger	520..540	CDD:275368
		C2H2 Zn finger	638..659	CDD:275368
		C2H2 Zn finger	668..690	CDD:275368
		C2H2 Zn finger	698..715	CDD:275368	4/11 (36%)
		C2H2 Zn finger	753..774	CDD:275368	2/20 (10%)
		C2H2 Zn finger	790..810	CDD:275368	6/19 (32%)
		zf-H2C2_2	802..825	CDD:290200	12/22 (55%)
		COG5048	814..>886	CDD:227381	25/60 (42%)
		C2H2 Zn finger	818..838	CDD:275368	7/19 (37%)
		zf-H2C2_2	830..855	CDD:290200	12/24 (50%)
		C2H2 Zn finger	846..866	CDD:275368	7/19 (37%)
		zf-H2C2_2	859..883	CDD:290200	5/15 (33%)
		C2H2 Zn finger	874..894	CDD:275368	57/182 (31%)
		C2H2 Zn finger	902..924	CDD:275368
Ikzf5	NP_001101025.1	C2H2 Zn finger	84..104	CDD:275368	6/19 (32%)
		zf-H2C2_2	96..121	CDD:404364	13/24 (54%)
		C2H2 Zn finger	112..132	CDD:275368	7/19 (37%)
		zf-H2C2_2	124..148	CDD:404364	12/25 (48%)
		C2H2 Zn finger	140..158	CDD:275368	8/22 (36%)
		PHA03269	251..>361	CDD:165527
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000