Protein Alignment CG18476 and Zfp39

DIOPT Version :10

• Sequence 1: NP_731615.1
• Gene: CG18476 / 41404
• FlyBaseID: FBgn0037931
• Length: 936
• Species: Drosophila melanogaster
• Sequence 2: NP_001100474.2
• Gene: Zfp39 / 303173
• RGDID: 1306633
• Length: 717
• Species: Rattus norvegicus
• Alignment Length: 563
• Identity: 137/563 - (24%)
• Similarity: 202/563 - (35%)
• Gaps: 174/563 - (30%)

  Fly   396 KATYSCELCQQKFPRKYQLYDHQRQSHSWSDAPHVCGRCDGRFVSLQLLRHHNESQCRNAQKRFL 460
            |.|:.|.:|::.|..|::|..|::                                ....||.|.
  Rat   296 KETFECSICKETFCTKFKLTKHKK--------------------------------IHKGQKYFT 328

  Fly   461 CHKCPLRFRWKHNLKTHFREHRI-----TNQTFECSECKRVFDKKKSLTVH--------LLSVHA 512
            |..|...|   .|...| ::.||     :::..:|..|   |.:|...:||        |..::.
  Rat   329 CRDCEKTF---INTSYH-KDQRIHVGVGSHRYKQCENC---FHQKNQQSVHQSVPKGSKLYEMYQ 386

  Fly   513 EES------------------KLIPCQWCSRKFYRHDYLVKHLKRHGLKEHDIPLAETLIAATSR 559
            .|.                  |...|..|.:.|||..:|.:|.:.|               ...|
  Rat   387 SEQSFSEKPNLRCCQKTRAGYKPYRCNMCGKSFYRKSHLSRHQRIH---------------TGER 436

  Fly   560 PNGAKRITCRMCNLHFERIVDLRAHIQLELKLSLSLHQSYDSPHNYSITNESGFELQLEDSETED 624
            |.|.|.  |:....|               |.||::||
  Rat   437 PYGCKE--CKKAFFH---------------KSSLTIHQ--------------------------- 457

  Fly   625 EMQPGVGSRPVYICELCSVQCKRKFEMIQHQRTMHRFDKMPHECDDCIFKCVSKSIMDHHRQGQC 689
              :...|.:| |.|:.|......|.::..|.|| |..:| |:|||:|.....|||.:..||  :.
  Rat   458 --RTHTGEKP-YECKKCRKTFYCKSDLNVHHRT-HTGEK-PYECDECRKTFYSKSHLIIHR--KI 515

  Fly   690 SSTEKKHACGKCSYKFMWPENLEQHILLQHSKSSVSNPTGDRHTQGTGDLEKDATEDGIPLLQCP 754
            .:.:|.:.|.:|...|....||..|                           ..|..|....:|.
  Rat   516 HTGDKPYECQECQKTFNRKSNLTVH---------------------------QKTHTGEKPYECD 553

  Fly   755 HCDRTYQMKSRLNNHIRDVHINGDRKRKEAIKRFLCSLCGMETRSAAALVTHMRRHTGEKPFKCD 819
            .|.:|:..:|.|:.| :.:| :|:       |.:.|..||......::|..|.|.|||::|:.|:
  Rat   554 VCGKTFHRQSHLSMH-QGIH-SGE-------KPYKCKECGKAFYQKSSLSRHQRNHTGDRPYACE 609

  Fly   820 LCEMAFPRHSELASHRRMHTGEKPFHCTVCGKDFARSDKLKRHMLTHSGLKPHKCTYCEKSYRQA 884
            .|...|...|.|..|:|.|||.||:.|..|.|.|.....|..|..||:|.||::|..|.|::.|.
  Rat   610 ECRKTFLHKSSLTVHQRSHTGYKPYSCEECRKTFYSKSHLTVHQRTHTGEKPYECKLCRKAFHQK 674

  Fly   885 KDLKLHLQQHTGECPFVCGTCGERFIQSSTLEKHRLMRRHFDE 927
            ..|..|...|..|..|.|..|.:||...|:|..|:  |.|..|
  Rat   675 SYLSRHQITHEREKRFECQECRKRFYHKSSLTVHQ--RIHLRE 715

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18476	NP_731615.1	C2H2 Zn finger	206..227	CDD:275368
		C2H2 Zn finger	236..256	CDD:275368
		C2H2 Zn finger	401..422	CDD:275368	6/20 (30%)
		C2H2 Zn finger	431..447	CDD:275368	0/15 (0%)
		C2H2 Zn finger	461..481	CDD:275368	5/19 (26%)
		C2H2 Zn finger	490..511	CDD:275368	7/28 (25%)
		C2H2 Zn finger	520..540	CDD:275368	7/19 (37%)
		C2H2 Zn finger	638..659	CDD:275368	6/20 (30%)
		C2H2 Zn finger	668..690	CDD:275368	8/21 (38%)
		C2H2 Zn finger	698..715	CDD:275368	5/16 (31%)
		C2H2 Zn finger	753..774	CDD:275368	6/20 (30%)
		C2H2 Zn finger	790..810	CDD:275368	6/19 (32%)
		COG5048	814..>886	CDD:227381	28/71 (39%)
		C2H2 Zn finger	818..838	CDD:275368	7/19 (37%)
		C2H2 Zn finger	846..866	CDD:275368	6/19 (32%)
		C2H2 Zn finger	874..894	CDD:275368	6/19 (32%)
		C2H2 Zn finger	902..924	CDD:275368	8/21 (38%)
Zfp39	NP_001100474.2	KRAB	59..118	CDD:214630
		COG5048	296..697	CDD:227381	129/541 (24%)
		C2H2 Zn finger	301..321	CDD:275368	6/51 (12%)
		C2H2 Zn finger	329..348	CDD:275368	6/22 (27%)
		C2H2 Zn finger	412..432	CDD:275368	7/19 (37%)
		C2H2 Zn finger	440..460	CDD:275368	8/65 (12%)
		C2H2 Zn finger	468..488	CDD:275368	6/20 (30%)
		C2H2 Zn finger	496..516	CDD:275368	8/21 (38%)
		C2H2 Zn finger	524..544	CDD:275368	6/46 (13%)
		C2H2 Zn finger	552..572	CDD:275368	6/20 (30%)
		C2H2 Zn finger	580..600	CDD:275368	6/19 (32%)
		C2H2 Zn finger	608..628	CDD:275368	7/19 (37%)
		C2H2 Zn finger	636..656	CDD:275368	6/19 (32%)
		C2H2 Zn finger	664..684	CDD:275368	6/19 (32%)
		C2H2 Zn finger	692..712	CDD:275368	8/21 (38%)