Protein Alignment CG18476 and Zfp473

DIOPT Version :10

• Sequence 1: NP_731615.1
• Gene: CG18476 / 41404
• FlyBaseID: FBgn0037931
• Length: 936
• Species: Drosophila melanogaster
• Sequence 2: NP_001414640.1
• Gene: Zfp473 / 292884
• RGDID: 1305084
• Length: 967
• Species: Rattus norvegicus
• Alignment Length: 949
• Identity: 231/949 - (24%)
• Similarity: 362/949 - (38%)
• Gaps: 245/949 - (25%)

  Fly    86 LKNGAAPTSTDC-------LQEAPMELCAEQHVEVKLETED---EDC-GEN--DVTITCSE-LPE 136
            ::.|...||.:.       ||...:|....|.:|: ..||:   |.| |||  |..:...| ||.
  Rat    86 VRGGPEATSDEATEAKNPPLQSGFLEEDLSQIMEI-FSTEELNFESCIGENWFDSFLGDPESLPR 149

  Fly   137 PD------ETDM---ESKKSVDP----LTMIETVKLEMEPRSVEKPAYDDPTSDFEDEDSLDNLP 188
            ||      .||.   ||:..:.|    .|....|..:...::::.....:..||...:||:.
  Rat   150 PDISNKESPTDRRCHESESGLSPGPPHCTREGAVMSDSPEKNLDPVILKESRSDLSQQDSVQ--- 211

  Fly   189 LYNRIQKWKTGRKSVYKCHDCPRSFKRFDFLKRHEMRVH-----------------------KPE 230
                      |::.:|||.:|.:||.:...|.:|.: :|                       :|.
  Rat   212 ----------GQEKLYKCSECGKSFSQSYHLIQHWV-IHARGELPAWQEQPGALSKGALLLMQPG 265

  Fly   231 TRL----YDCSLCIRKFSRSEALEAHLKIHRNSKRSANISEHKKAKAVDLNLCKPH-------GY 284
            |:.    |.|..|.:.||::..|:.|.|||...|.....|:         ||.||.       |.
  Rat   266 TQTSSESYVCQECGKSFSQNMYLQWHQKIHTGEKLCKTQSD---------NLEKPSKGPSDEPGK 321

  Fly   285 KLIECMICQSQYNKIADLRRHLEEHPDIVSLCGRPNMEPHELAELF---YPDSKDLSEEQLINLI 346
            :|:.   ..:...|:.|.|...:|.|        |..:.|:..:|.   |.||..:...:.|...
  Rat   322 QLVS---EAADSAKLCDSRGWDQEKP--------PTNKRHDREDLHKGQYGDSPSVLHPKPIKHQ 375

  Fly   347 RKDLAAGIY-----------------------QRFYSITNQSGYEMDLDSSETDSDLDGDHDDQH 388
            :....|..:                       ||.|..|          |.....:| ..|..||
  Rat   376 KTATRAKCFRCRRCGKTFSWAFHLADHQKVHTQRLYGCT----------SCPAVFNL-RKHFFQH 429

  Fly   389 KRRKKSRKATYSCELCQQKFPRKYQLYDHQRQSHSWSDAPHVCGRCDGRFVSLQLLRHHNESQCR 453
             |:....|..:.|:.|::.|.|:..|..|| ..|: .:.|:.|..|...|.....|:.|  .:..
  Rat   430 -RKTHFAKTVFECQECRKLFNRRSSLIKHQ-AVHT-GEKPYKCNECGKAFNHFSTLKIH--QRIH 489

  Fly   454 NAQKRFLCHKCPLRFRWK------HNLKTHFREHRITNQTFECSECKRVFDKKKSLTVHLLSVHA 512
            :.:|.:.|.:|...|..:      |.:.:.||.|       :|..|.|.|.:...||.|.|| ||
  Rat   490 SGEKPYTCSECGKTFSRRTALTEHHRVHSGFRPH-------QCPVCPRRFSRPSHLTRHQLS-HA 546

  Fly   513 EESKLIPCQWCSRKFYRHDYLVKHLKRHGLKEHDIPLAETLIAATSRPNGAKRITCRMCNLHFER 577
            .| :|..|..|...|...:.|.:|.|.|.::                    ....|:.|..||..
  Rat   547 AE-RLFGCAKCKETFGHKEQLERHYKSHTIE--------------------CSYECKQCGEHFIC 590

  Fly   578 IVDLRAHIQLELKLSLSLHQSYDSPHNY------------SITNESGFELQLEDSETEDEMQPGV 630
            ...|..|:.:.::.:.|  :.....|:.            ...|.|.:      .|..:::...|
  Rat   591 SSTLNCHLSIHIRENTS--EKVSGQHSQHTEKCFKNTKCGKAFNHSKY------PEQHEKIHAKV 647

  Fly   631 GSRPVYICEL--CSVQCKRKFEMIQHQRTMHRFDKMPHECDDCIFKCVSKSIMDHHRQGQCSSTE 693
            .|     ||.  |...|.:..:.|..|.:....  .|::|.: ..||:..:.:..|   |.|.:|
  Rat   648 AS-----CEQSPCRNTCDQSMQPIHCQSSCAAV--KPNKCTE-PEKCIRNTSVSQH---QPSQSE 701

  Fly   694 KKHACGKCSYKFMWPENLEQHILLQHSKSSVSNPTGDRHTQGTGDLEKDATEDGIPLLQCPHCDR 758
            ....|..|:..|....:|..|.|:              ||     .||.        .:|..|||
  Rat   702 PPFKCNTCNRTFKQSAHLSNHQLI--------------HT-----TEKP--------FKCKECDR 739

  Fly   759 TYQMKSRLNNHIRDVHINGDRKRKEAIKRFLCSLCGMETRSAAALVTHMRRHTGEKPFKCDLCEM 823
            .::..:.|..| :.:|         ::|.|.||.||.:....:.|..|.:.|:|:|||||..|..
  Rat   740 AFKHSNYLIQH-QKIH---------SVKDFECSECGKKFHQKSCLSKHQKIHSGQKPFKCADCGK 794

  Fly   824 AFPRHSELASHRRMHTGEKPFHCTVCGKDFARSDKLKRHMLTHSGLKPHKCTYCEKSYRQAKDLK 888
            ||...::|..|:|:||||||:.|..|||.|::|..|..|:.||:|.||:.|:.|.|::.|..:.:
  Rat   795 AFIFSAQLIRHQRIHTGEKPYVCQECGKAFSQSSCLTLHLRTHTGEKPYTCSTCGKAFSQKANQR 859

  Fly   889 LHLQQHTGECPFVCGTCGERFIQSSTLEKHRLMRRHFDE 927
            .|.:.|:||.|..|..||:.|..|:.|.:|:  |.|..|
  Rat   860 KHERTHSGEKPCACDVCGKSFGFSTHLRQHQ--RIHTKE 896

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18476	NP_731615.1	C2H2 Zn finger	206..227	CDD:275368	6/20 (30%)
		C2H2 Zn finger	236..256	CDD:275368	7/19 (37%)
		C2H2 Zn finger	401..422	CDD:275368	7/20 (35%)
		C2H2 Zn finger	431..447	CDD:275368	4/15 (27%)
		C2H2 Zn finger	461..481	CDD:275368	6/25 (24%)
		C2H2 Zn finger	490..511	CDD:275368	9/20 (45%)
		C2H2 Zn finger	520..540	CDD:275368	6/19 (32%)
		C2H2 Zn finger	638..659	CDD:275368	6/22 (27%)
		C2H2 Zn finger	668..690	CDD:275368	5/21 (24%)
		C2H2 Zn finger	698..715	CDD:275368	4/16 (25%)
		C2H2 Zn finger	753..774	CDD:275368	6/20 (30%)
		C2H2 Zn finger	790..810	CDD:275368	6/19 (32%)
		COG5048	814..>886	CDD:227381	34/71 (48%)
		C2H2 Zn finger	818..838	CDD:275368	7/19 (37%)
		C2H2 Zn finger	846..866	CDD:275368	8/19 (42%)
		C2H2 Zn finger	874..894	CDD:275368	5/19 (26%)
		C2H2 Zn finger	902..924	CDD:275368	8/21 (38%)
Zfp473	NP_001414640.1	None