Protein Alignment CG18476 and Ikzf4

DIOPT Version :9

• Sequence 1: NP_731615.1
• Gene: CG18476 / 41404
• FlyBaseID: FBgn0037931
• Length: 936
• Species: Drosophila melanogaster
• Sequence 2: NP_035902.2
• Gene: Ikzf4 / 22781
• MGIID: 1343139
• Length: 586
• Species: Mus musculus
• Alignment Length: 263
• Identity: 75/263 - (28%)
• Similarity: 111/263 - (42%)
• Gaps: 45/263 - (17%)

  Fly   684 HRQGQCSSTEKKHACGKCSYKFMWPENLEQHILLQHSKSSVSNPTGDRHTQGTGDLEKDATEDGI 748
            ||||:  ...::...|.|:..|:.......|.:::   |.....:||      ..|||:.....:
Mouse    23 HRQGK--DNLERELSGGCAPDFLPQAQDSNHFIME---SLFCESSGD------SSLEKEFLGAPV 76

  Fly   749 -PLLQCPHCDRTYQMKSRLNNHIRDVHINGDRKRKEAI---KRFL------------------CS 791
             |.:..|:...:...:|...|.|: |.:..|.:....:   :|.|                  |.
Mouse    77 GPSVSTPNSQHSSPSRSLSANSIK-VEMYSDEESSRLLGPDERLLDKDDSVIVEDSLSEPLGYCD 140

  Fly   792 LCGMETRSAAALVTHMRRHTGEKPFKCDLCEMAFPRHSELASHRRMHTGEKPFHCTVCGKDFARS 856
            ..|.|..|...:    |...|:  .|||:|.|.....:.|..|:|.||||:||||..||..|.:.
Mouse   141 GSGPEPHSPGGI----RLPNGK--LKCDVCGMVCIGPNVLMVHKRSHTGERPFHCNQCGASFTQK 199

  Fly   857 DKLKRHMLTHSGLKPHKCTYCEKSYRQAKDLKLHLQQHTGECPFV-----CGTCGERFIQSSTLE 916
            ..|.||:..|||.||.||.:|..:.|:...|..||:.|:...|.|     |..||..:.|.||||
Mouse   200 GNLLRHIKLHSGEKPFKCPFCNYACRRRDALTGHLRTHSVSSPTVGKPYKCNYCGRSYKQQSTLE 264

  Fly   917 KHR 919
            :|:
Mouse   265 EHK 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18476	NP_731615.1	zf-AD	6..84	CDD:285071
		C2H2 Zn finger	206..227	CDD:275368
		C2H2 Zn finger	236..256	CDD:275368
		C2H2 Zn finger	401..422	CDD:275368
		C2H2 Zn finger	431..447	CDD:275368
		C2H2 Zn finger	461..481	CDD:275368
		C2H2 Zn finger	490..511	CDD:275368
		C2H2 Zn finger	520..540	CDD:275368
		C2H2 Zn finger	638..659	CDD:275368
		C2H2 Zn finger	668..690	CDD:275368	4/5 (80%)
		C2H2 Zn finger	698..715	CDD:275368	3/16 (19%)
		C2H2 Zn finger	753..774	CDD:275368	4/20 (20%)
		C2H2 Zn finger	790..810	CDD:275368	5/19 (26%)
		zf-H2C2_2	802..825	CDD:290200	7/22 (32%)
		COG5048	814..>886	CDD:227381	31/71 (44%)
		C2H2 Zn finger	818..838	CDD:275368	7/19 (37%)
		zf-H2C2_2	830..855	CDD:290200	14/24 (58%)
		C2H2 Zn finger	846..866	CDD:275368	7/19 (37%)
		zf-H2C2_2	859..883	CDD:290200	11/23 (48%)
		C2H2 Zn finger	874..894	CDD:275368	6/19 (32%)
		C2H2 Zn finger	902..924	CDD:275368	9/18 (50%)
Ikzf4	NP_035902.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..42		6/20 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	68..98		5/29 (17%)
		C2H2 Zn finger	161..181	CDD:275368	7/19 (37%)
		zf-H2C2_2	174..198	CDD:290200	14/23 (61%)
		C2H2 Zn finger	189..209	CDD:275368	7/19 (37%)
		zf-H2C2_2	201..226	CDD:290200	11/24 (46%)
		C2H2 Zn finger	217..237	CDD:275368	6/19 (32%)
		C2H2 Zn finger	250..271	CDD:275368	9/18 (50%)
		Interaction with FOXP3. /evidence=ECO:0000269|PubMed:19696312	281..586
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	413..490
		CTBP-binding motif PEDLG	423..433
		C2H2 Zn finger	533..553	CDD:275368

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000