Protein Alignment CG18476 and Zfp62

DIOPT Version :10

• Sequence 1: NP_731615.1
• Gene: CG18476 / 41404
• FlyBaseID: FBgn0037931
• Length: 936
• Species: Drosophila melanogaster
• Sequence 2: NP_033588.2
• Gene: Zfp62 / 22720
• MGIID: 99662
• Length: 914
• Species: Mus musculus
• Alignment Length: 871
• Identity: 217/871 - (24%)
• Similarity: 332/871 - (38%)
• Gaps: 213/871 - (24%)

  Fly    71 YVKQAMAANELLMKHLKNGAAPTSTDCLQEAPMELCAEQHVEVKLETEDEDCGENDVTITCSELP 135
            |:|..|...|...|:..:..|.:     |...:....:.|:: |.:|.|          ||...|
Mouse     3 YLKTTMEDEESSKKNENDSNADS-----QCPSVGFFHKDHMQ-KSKTGD----------TCDLFP 51

  Fly   136 E---PDETDMESKKSVDPLTMIETVKLEMEPRSVEKPAY-----------DDPTSDFEDEDSLDN 186
            :   ..|.....::.:|..|....:|||.:..:.||..|           .:|....:.|.: :|
Mouse    52 KWKILKEGKSSIREMIDTHTNAANIKLEQDDETSEKSFYPSTNTMHQTIPTEPNCTKQGEHT-EN 115

  Fly   187 LPLYNRIQKWKTGRKSVYKCHDCPRSFKRFDFLKRHEMRVHKPETRLYDCSLCIRKFSRSEALEA 251
              :...:.......|.::||.:|.:|||....|.:|:: :|..|.| |:|..|...|..|.:|..
Mouse   116 --INGNVHPAHIADKKLHKCDECGKSFKYNSRLVQHKI-MHTGEKR-YECDDCRGTFRSSSSLRV 176

  Fly   252 HLKIHRNSKRSANISEHKKAKAVDLNLCKPHGYKLIECMICQSQYNKIADLRRHLEEHPDIVSLC 316
            |.:||.                         |.|..:|..|...|...:.|..|...|      .
Mouse   177 HKRIHT-------------------------GEKPYKCDECGKAYMSYSSLINHKSTH------S 210

  Fly   317 GRPNMEPHELAELF-YPDSKDLSEEQLINLIRKDLAAGIYQRFYSITNQSGYEMDLDSSETDSDL 380
            |..|.:..|..:.| |  |..|.:.:.|:...|....|...:  :..|.||..:
Mouse   211 GEKNCKCDECGKSFNY--SSVLDQHKRIHTGEKPYECGECGK--AFRNSSGLRV----------- 260

  Fly   381 DGDHDDQHKRRKKSRKATYSCELCQQKFPRKYQLYDHQRQSHSWSDAPHVCGRCDGRFVSLQLLR 445
                   |||.....| .|.|:.|.:.|.....|..|:| .|: .:.|:.|..|...|::.:.|.
Mouse   261 -------HKRIHTGEK-PYECDTCGKTFSNSSGLRVHKR-IHT-GEKPYECDECGKAFITCRTLL 315

  Fly   446 HHNESQCRNAQKRFLCHKCPLRFRWKHNLKTHFREHRITN---QTFECSECKRVFDKKKSLTVHL 507
            :|  .......|.:.|.:|...|    |..:...:|::.:   :.:||.||.:.|.....|.||
Mouse   316 NH--KSIHFGDKPYKCDECEKSF----NYSSLLIQHKVIHTGEKPYECDECGKAFRNSSGLIVH- 373

  Fly   508 LSVHAEESKLIPCQWCSRKFYRHDYLVKHLKRH-GLKEHDIPLAETLIAATSRPNGAKRITCRMC 571
            ..:|..| |...|..|.:.|.....|..|...| |.|.|:                     |:.|
Mouse   374 KRIHTGE-KPYKCDICGKAFSYSSGLAVHKSIHPGKKAHE---------------------CKDC 416

  Fly   572 NLHFERIVDLRAHIQLELKLSLSLHQSYDSPHNYSITNESGFELQLEDSETEDEMQPGVGSRPVY 636
            ...|                      ||:|           ..||.:...|        |.|| |
Mouse   417 GKSF----------------------SYNS-----------LLLQHKTIHT--------GERP-Y 439

  Fly   637 ICELCSVQCKRKFEMIQHQRTMHRFDKMPHECDDCIFKCVSKSIMDHHR---QGQCSSTEKKHAC 698
            :|::|....:....:..|:| :|..:| |::||.|....:|:|.:.:|:   .|     ||.:.|
Mouse   440 VCDVCGKTFRNNSGLKVHRR-LHTGEK-PYKCDVCGKAYISRSSLKNHKGIHMG-----EKPYKC 497

  Fly   699 GKCSYKFMWPENLEQHILLQHSKSSVSNPTGDRHTQGTGDLEKDATEDGIPLLQCPHCDRTYQMK 763
            ..|...|.:...||||..: |::   ..|.|                       |..|.:.::..
Mouse   498 SYCEKSFNYSSALEQHKRI-HTR---EKPFG-----------------------CDECGKAFRNN 535

  Fly   764 SRLNNHIRDVHINGDRKRKEAIKRFLCSLCGMETRSAAALVTHMRRHTGEKPFKCDLCEMAFPRH 828
            |.|..|.| :| .|:|..|       |..||....|.::|:.|...|.||||||||.||.||..:
Mouse   536 SGLKVHKR-IH-TGERPYK-------CEECGKAYISLSSLINHKSVHPGEKPFKCDECEKAFITY 591

  Fly   829 SELASHRRMHTGEKPFHCTVCGKDFARSDKLKRHMLTHSGLKPHKCTYCEKSYRQAKDLKLHLQQ 893
            ..|.:|:::|.||||:.|.||.|.|..:..|.:|...|:..||.:|..|||.:|....||:|.:.
Mouse   592 RTLLNHKKIHLGEKPYKCDVCEKSFNYTSLLSQHKRVHTREKPFECDRCEKVFRNNSSLKVHKRI 656

  Fly   894 HTGECPFVCGTCGERFIQSSTLEKHR 919
            ||||.|:.|..||:.:|..|:|..|:
Mouse   657 HTGEKPYECDICGKAYISHSSLINHK 682

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18476	NP_731615.1	C2H2 Zn finger	206..227	CDD:275368	7/20 (35%)
		C2H2 Zn finger	236..256	CDD:275368	6/19 (32%)
		C2H2 Zn finger	401..422	CDD:275368	6/20 (30%)
		C2H2 Zn finger	431..447	CDD:275368	4/15 (27%)
		C2H2 Zn finger	461..481	CDD:275368	4/19 (21%)
		C2H2 Zn finger	490..511	CDD:275368	7/20 (35%)
		C2H2 Zn finger	520..540	CDD:275368	5/19 (26%)
		C2H2 Zn finger	638..659	CDD:275368	4/20 (20%)
		C2H2 Zn finger	668..690	CDD:275368	7/24 (29%)
		C2H2 Zn finger	698..715	CDD:275368	6/16 (38%)
		C2H2 Zn finger	753..774	CDD:275368	6/20 (30%)
		C2H2 Zn finger	790..810	CDD:275368	6/19 (32%)
		COG5048	814..>886	CDD:227381	32/71 (45%)
		C2H2 Zn finger	818..838	CDD:275368	8/19 (42%)
		C2H2 Zn finger	846..866	CDD:275368	7/19 (37%)
		C2H2 Zn finger	874..894	CDD:275368	8/19 (42%)
		C2H2 Zn finger	902..924	CDD:275368	7/18 (39%)
Zfp62	NP_033588.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..35		7/36 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	80..101		3/20 (15%)
		COG5048	127..542	CDD:227381	129/577 (22%)
		C2H2 Zn finger	133..153	CDD:275368	7/20 (35%)
		C2H2 Zn finger	161..181	CDD:275368	6/19 (32%)
		C2H2 Zn finger	189..209	CDD:275368	5/19 (26%)
		C2H2 Zn finger	217..237	CDD:275368	5/21 (24%)
		C2H2 Zn finger	245..265	CDD:275368	7/39 (18%)
		C2H2 Zn finger	273..293	CDD:275368	6/20 (30%)
		C2H2 Zn finger	301..321	CDD:275368	5/21 (24%)
		C2H2 Zn finger	329..349	CDD:275368	5/23 (22%)
		C2H2 Zn finger	357..377	CDD:275368	7/20 (35%)
		SFP1	<379..458	CDD:227516	26/142 (18%)
		C2H2 Zn finger	385..405	CDD:275368	5/19 (26%)
		C2H2 Zn finger	413..433	CDD:275368	8/52 (15%)
		COG5048	437..850	CDD:227381	95/290 (33%)
		C2H2 Zn finger	441..461	CDD:275368	4/20 (20%)
		C2H2 Zn finger	469..489	CDD:275368	6/19 (32%)
		C2H2 Zn finger	497..517	CDD:275368	7/20 (35%)
		C2H2 Zn finger	525..545	CDD:275368	6/20 (30%)
		C2H2 Zn finger	553..573	CDD:275368	6/19 (32%)
		C2H2 Zn finger	581..601	CDD:275368	8/19 (42%)
		C2H2 Zn finger	609..629	CDD:275368	7/19 (37%)
		C2H2 Zn finger	637..657	CDD:275368	8/19 (42%)
		C2H2 Zn finger	665..685	CDD:275368	7/18 (39%)
		C2H2 Zn finger	693..713	CDD:275368
		C2H2 Zn finger	721..741	CDD:275368
		C2H2 Zn finger	749..769	CDD:275368
		C2H2 Zn finger	777..797	CDD:275368
		C2H2 Zn finger	805..824	CDD:275368
		C2H2 Zn finger	832..852	CDD:275368