Protein Alignment CG18476 and EGR1

DIOPT Version :10

• Sequence 1: NP_731615.1
• Gene: CG18476 / 41404
• FlyBaseID: FBgn0037931
• Length: 936
• Species: Drosophila melanogaster
• Sequence 2: NP_001955.1
• Gene: EGR1 / 1958
• HGNCID: 3238
• Length: 543
• Species: Homo sapiens
• Alignment Length: 137
• Identity: 49/137 - (35%)
• Similarity: 68/137 - (49%)
• Gaps: 13/137 - (9%)

  Fly   743 ATEDGIPLLQCPHCDRTYQMK----SRLNNHIRDVHINGDRKRKEAIKRFLCSL--CGMETRSAA 801
            ||:.|...|:.  .:.:||.:    ||:..     :.|...|.....:.:.|.:  |......:.
Human   296 ATQSGSQDLKA--LNTSYQSQLIKPSRMRK-----YPNRPSKTPPHERPYACPVESCDRRFSRSD 353

  Fly   802 ALVTHMRRHTGEKPFKCDLCEMAFPRHSELASHRRMHTGEKPFHCTVCGKDFARSDKLKRHMLTH 866
            .|..|:|.|||:|||:|.:|...|.|...|.:|.|.|||||||.|.:||:.|||||:.|||...|
Human   354 ELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIH 418

  Fly   867 SGLKPHK 873
            ...|..|
Human   419 LRQKDKK 425

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18476	NP_731615.1	C2H2 Zn finger	206..227	CDD:275368
		C2H2 Zn finger	236..256	CDD:275368
		C2H2 Zn finger	401..422	CDD:275368
		C2H2 Zn finger	431..447	CDD:275368
		C2H2 Zn finger	461..481	CDD:275368
		C2H2 Zn finger	490..511	CDD:275368
		C2H2 Zn finger	520..540	CDD:275368
		C2H2 Zn finger	638..659	CDD:275368
		C2H2 Zn finger	668..690	CDD:275368
		C2H2 Zn finger	698..715	CDD:275368
		C2H2 Zn finger	753..774	CDD:275368	4/24 (17%)
		C2H2 Zn finger	790..810	CDD:275368	5/21 (24%)
		COG5048	814..>886	CDD:227381	31/60 (52%)
		C2H2 Zn finger	818..838	CDD:275368	7/19 (37%)
		C2H2 Zn finger	846..866	CDD:275368	11/19 (58%)
		C2H2 Zn finger	874..894	CDD:275368	49/137 (36%)
		C2H2 Zn finger	902..924	CDD:275368
EGR1	NP_001955.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..105
		DUF3446	135..237	CDD:463400
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	165..213
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	264..284
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	318..339		4/25 (16%)
		zf-C2H2	338..362	CDD:395048	5/23 (22%)
		C2H2 Zn finger	340..362	CDD:275368	5/21 (24%)
		zf-H2C2_2	354..379	CDD:463886	12/24 (50%)
		C2H2 Zn finger	370..390	CDD:275368	7/19 (37%)
		zf-H2C2_2	382..407	CDD:463886	14/24 (58%)
		C2H2 Zn finger	398..418	CDD:275368	11/19 (58%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	409..487		7/17 (41%)
		DUF3432	447..530	CDD:403204