Protein Alignment CG18476 and ZNF648

DIOPT Version :10

• Sequence 1: NP_731615.1
• Gene: CG18476 / 41404
• FlyBaseID: FBgn0037931
• Length: 936
• Species: Drosophila melanogaster
• Sequence 2: NP_001009992.1
• Gene: ZNF648 / 127665
• HGNCID: 18190
• Length: 568
• Species: Homo sapiens
• Alignment Length: 297
• Identity: 106/297 - (35%)
• Similarity: 153/297 - (51%)
• Gaps: 17/297 - (5%)

  Fly   625 EMQPGVGSRPVYICELCSVQCKRKFEMIQHQRTMHRFDKMPHECDDCIFKCVSKSIMDHHRQGQC 689
            |.:.|...|  |.||||......:..:.||:| :|..:: |::|..| .|..:.| .||.:..:.
Human   270 ETRGGAAKR--YACELCGKAYSHRGTLQQHRR-LHTGER-PYQCSFC-DKAYTWS-SDHRKHIRT 328

  Fly   690 SSTEKKHACGKCSYKFMWPENLEQHILLQHS--KSSVSNPTGDRHTQGTGDLEKDATEDGIPLLQ 752
            .:.||.:.|..|...|:...:|.:|....||  |....:..|....:....|....|..|....:
Human   329 HTGEKPYPCPDCGKAFVRSSDLRKHQRNMHSNNKPFPCSECGLTFNKPLSLLRHQRTHLGAKPFR 393

  Fly   753 CPHCDRTYQMKSRLNNHIRDVHINGDRKRKEAIKRFLCSLCGMETRSAAALVTHMRRHTGEKPFK 817
            ||.|||.:.:.||:..|.| || :|:|.       |.|..||.....::.|..|...|||::|||
Human   394 CPACDREFAVASRMVEHQR-VH-SGERP-------FPCPTCGKCFTKSSNLSEHQTLHTGQRPFK 449

  Fly   818 CDLCEMAFPRHSELASHRRMHTGEKPFHCTVCGKDFARSDKLKRHMLTHSGLKPHKCTYCEKSYR 882
            |..|.:||.:.|.|..|:|:||||:||.||.||:.||||..||||...|||.|...|..|.:::|
Human   450 CADCGVAFAQPSRLVRHQRIHTGERPFPCTQCGQAFARSSTLKRHQQIHSGEKGFLCAECGRAFR 514

  Fly   883 QAKDLKLHLQQHTGECPFVCGTCGERFIQSSTLEKHR 919
            .|.:|..|::.|.||.|:.|..||:.|.:|:.|::||
Human   515 IASELAQHIRMHNGERPYQCEDCGQAFTRSNHLQRHR 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18476	NP_731615.1	C2H2 Zn finger	206..227	CDD:275368
		C2H2 Zn finger	236..256	CDD:275368
		C2H2 Zn finger	401..422	CDD:275368
		C2H2 Zn finger	431..447	CDD:275368
		C2H2 Zn finger	461..481	CDD:275368
		C2H2 Zn finger	490..511	CDD:275368
		C2H2 Zn finger	520..540	CDD:275368
		C2H2 Zn finger	638..659	CDD:275368	7/20 (35%)
		C2H2 Zn finger	668..690	CDD:275368	6/21 (29%)
		C2H2 Zn finger	698..715	CDD:275368	4/16 (25%)
		C2H2 Zn finger	753..774	CDD:275368	9/20 (45%)
		C2H2 Zn finger	790..810	CDD:275368	5/19 (26%)
		COG5048	814..>886	CDD:227381	37/71 (52%)
		C2H2 Zn finger	818..838	CDD:275368	8/19 (42%)
		C2H2 Zn finger	846..866	CDD:275368	12/19 (63%)
		C2H2 Zn finger	874..894	CDD:275368	6/19 (32%)
		C2H2 Zn finger	902..924	CDD:275368	8/18 (44%)
ZNF648	NP_001009992.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..106
		C2H2 Zn finger	281..301	CDD:275368	7/20 (35%)
		zf-H2C2_2	294..317	CDD:463886	8/25 (32%)
		COG5048	<307..494	CDD:227381	69/197 (35%)
		C2H2 Zn finger	309..329	CDD:275368	6/21 (29%)
		C2H2 Zn finger	337..355	CDD:275368	5/17 (29%)
		C2H2 Zn finger	366..386	CDD:275368	2/19 (11%)
		C2H2 Zn finger	394..414	CDD:275368	9/20 (45%)
		C2H2 Zn finger	422..442	CDD:275368	5/19 (26%)
		C2H2 Zn finger	450..470	CDD:275368	8/19 (42%)
		C2H2 Zn finger	478..498	CDD:275368	12/19 (63%)
		C2H2 Zn finger	506..526	CDD:275368	6/19 (32%)
		zf-H2C2_2	518..543	CDD:463886	10/24 (42%)
		C2H2 Zn finger	534..554	CDD:275368	8/18 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	548..568		2/4 (50%)