DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG18476 and znf229

DIOPT Version :10

Sequence 1:NP_731615.1 Gene:CG18476 / 41404 FlyBaseID:FBgn0037931 Length:936 Species:Drosophila melanogaster
Sequence 2:XP_004916266.1 Gene:znf229 / 100492389 XenbaseID:XB-GENE-6051225 Length:704 Species:Xenopus tropicalis


Alignment Length:868 Identity:196/868 - (22%)
Similarity:308/868 - (35%) Gaps:272/868 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   117 TEDEDCGENDVTITCSELPEPDETDMESKK-----SVDPLTMIETVK-----LEMEPRSVEKPAY 171
            ||.:|  |.|...||     |..| |||.|     |..||.|..:|:     :.|:..:::|  :
 Frog    10 TEIDD--EKDGPETC-----PKNT-MESPKPLSYSSTSPLAMSTSVQSLHDGMAMKMGNLQK--F 64

  Fly   172 DDPTSDFEDEDSLDNLPLYNRIQKWKTGRKSVYKCHDCPRS---------FKRFDFLKR---HEM 224
            |.|           ::|...  .|.:.|....|  |:.|.|         |:.|.::..   |: 
 Frog    65 DVP-----------DIPALK--AKEEPGELKYY--HESPDSRNELKCGLCFETFQYVSEFMFHD- 113

  Fly   225 RVHKPETRLYDCSLCIRKFSRSEALEAHLKIHRNSKRSANISEHKKAKAVDLNLCKPHGYKLIEC 289
            ::||...| ::|.||.|:|..:..|:.|..:|.                         |.:..:|
 Frog   114 QIHKATNR-FECQLCGRQFQSTSNLKDHYNVHT-------------------------GERPYKC 152

  Fly   290 MICQSQYNKIADL----RRHLEEHPDIVSLCGRPNMEPHELAELFYPDSKDLSEEQLINLIRKDL 350
            .:|...:.:.:.|    |.|..|:|....:|||          ||    :|.|     |.::   
 Frog   153 ELCAKAFTQSSSLLTHKRTHTMENPYKCEVCGR----------LF----RDAS-----NFVK--- 195

  Fly   351 AAGIYQRFYSITNQSGYEMDLDSSETDSDLDGDHDDQHKRRKKSRKATYSCELCQQKFPRKYQLY 415
                ::|.:|...|.|.:                  .|...:...:..|.|..|::.|.|...|.
 Frog   196 ----HRRLHSQAQQLGRQ------------------AHSASQIISEKPYQCSYCEKSFKRTSDLK 238

  Fly   416 DHQRQSHSWSDAPHVCGRCDGRFVSLQLLRHHNESQCRNAQKRFLCHKCPLRFRWKHNLKTHFRE 480
            ||:| .|: .:.|:.|..|...|....:|..|  .:....::.|.|..|...|....|.|.|.|.
 Frog   239 DHER-VHT-GERPYRCRICQKCFTQSSVLTGH--MRIHTGERPFHCDICGKTFNNSSNFKKHQRT 299

  Fly   481 HRITNQTFECSECKRVFDKKKSLT----------VHLLS----VHAEESKLIPCQWCSRKFYRHD 531
            |.:.:.....|...|....|:.|.          ::.:|    :...:::..|            
 Frog   300 HSVQDMLANVSRDARFSHYKQPLRSKNGIGFSRGINAISYGKDISVNQTRTFP------------ 352

  Fly   532 YLVKHLKRHGLKEHDIPLAETLIAATSRPNGAKRITCRMCNLHFERIVDLR---AHIQLELKLSL 593
                   :..|.|.|..|  .|...||:.||..        :|  .:.||.   |.:     .:|
 Frog   353 -------KMNLNEEDCEL--VLEKNTSQGNGDV--------IH--DVDDLSSPCAGV-----TNL 393

  Fly   594 SLHQSYDSPHNYSITNESGFELQLEDSE------TEDEMQPGVGSRPVYICELCSVQCKRKFE-- 650
            :.|    :..|.|...|:|..:.....|      |:|:...|..      .|...:..|.|||  
 Frog   394 TKH----TDENISEAKETGATVIFHSDEVIAIDDTDDKEDLGAE------FETKELSPKDKFEKQ 448

  Fly   651 ----------------------MIQHQRTMHRFDKMPH-ECDDCIFKCVSKSI--MDHHRQGQCS 690
                                  .|:|... |:.:..|: ..:|.:..|:....  :...|....|
 Frog   449 ILPKLARSTGPRYKITTPYWDNYIKHSFN-HKMELNPYITGEDLVKTCLQSQDEGLKEARNEDGS 512

  Fly   691 STEKKHACGKCSYKFMWPENL------EQHILLQHSKSSVSNPTGD------RHTQGTGDLEKDA 743
            :.:.......|.     ||.|      |||.....|..|.|:..|:      ..|.|..:...|.
 Frog   513 TYDLSKDLEVCR-----PEKLSSGMDKEQHESEVISDGSSSSDIGESENLLLERTMGCWNQSIDD 572

  Fly   744 T----EDGIPLLQCPHCDRTYQMKSRLNNHIRDVHINGDRKRKEAIKRFLCSLCGMETRSAAALV 804
            |    :|...||       ..:|:|                     |.::|.:|....:.|..|.
 Frog   573 TIDYQDDDDDLL-------FLEMES---------------------KPYICFVCSKRFKRATDLK 609

  Fly   805 THMRRHTGEKPFKCDLCEMAFPRHSELASHRRMHTGEKPFHCTVCGKDFARSDKLKRHMLTHSGL 869
            .|:|.||||:||.|.:|...|.:.|.|:||:|:|||||||.|.:|.|.|..|....:|...|:|.
 Frog   610 EHLRVHTGERPFVCQVCGKGFTQSSALSSHQRIHTGEKPFQCEICYKRFNNSSNFSKHKRVHTGE 674

  Fly   870 KPHKCTYCEKSYRQAKDLKLHLQ 892
            :||.|..|.||:::.:.:|.||:
 Frog   675 RPHNCPICGKSFQEKRRVKRHLR 697

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG18476NP_731615.1 C2H2 Zn finger 206..227 CDD:275368 6/32 (19%)
C2H2 Zn finger 236..256 CDD:275368 7/19 (37%)
C2H2 Zn finger 401..422 CDD:275368 8/20 (40%)
C2H2 Zn finger 431..447 CDD:275368 4/15 (27%)
C2H2 Zn finger 461..481 CDD:275368 7/19 (37%)
C2H2 Zn finger 490..511 CDD:275368 5/34 (15%)
C2H2 Zn finger 520..540 CDD:275368 0/19 (0%)
C2H2 Zn finger 638..659 CDD:275368 7/44 (16%)
C2H2 Zn finger 668..690 CDD:275368 3/23 (13%)
C2H2 Zn finger 698..715 CDD:275368 6/22 (27%)
C2H2 Zn finger 753..774 CDD:275368 2/20 (10%)
C2H2 Zn finger 790..810 CDD:275368 6/19 (32%)
COG5048 814..>886 CDD:227381 31/71 (44%)
C2H2 Zn finger 818..838 CDD:275368 8/19 (42%)
C2H2 Zn finger 846..866 CDD:275368 6/19 (32%)
C2H2 Zn finger 874..894 CDD:275368 7/19 (37%)
C2H2 Zn finger 902..924 CDD:275368
znf229XP_004916266.1 C2H2 Zn finger 96..116 CDD:275368 3/20 (15%)
COG5048 <119..296 CDD:227381 52/250 (21%)
C2H2 Zn finger 124..144 CDD:275368 7/19 (37%)
C2H2 Zn finger 152..172 CDD:275368 4/19 (21%)
C2H2 Zn finger 180..200 CDD:275368 9/45 (20%)
C2H2 Zn finger 224..244 CDD:275368 8/20 (40%)
COG5048 248..697 CDD:227381 121/530 (23%)
C2H2 Zn finger 252..272 CDD:275368 5/21 (24%)
C2H2 Zn finger 280..300 CDD:275368 7/19 (37%)
C2H2 Zn finger 595..615 CDD:275368 6/19 (32%)
C2H2 Zn finger 623..643 CDD:275368 8/19 (42%)
C2H2 Zn finger 651..671 CDD:275368 6/19 (32%)
C2H2 Zn finger 679..697 CDD:275368 6/17 (35%)
Blue background indicates that the domain is not in the aligned region.

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