Protein Alignment CG18476 and Zfp267

DIOPT Version :10

• Sequence 1: NP_731615.1
• Gene: CG18476 / 41404
• FlyBaseID: FBgn0037931
• Length: 936
• Species: Drosophila melanogaster
• Sequence 2: NP_001395762.1
• Gene: Zfp267 / 100359945
• RGDID: 2323100
• Length: 796
• Species: Rattus norvegicus
• Alignment Length: 965
• Identity: 224/965 - (23%)
• Similarity: 339/965 - (35%)
• Gaps: 272/965 - (28%)

  Fly    39 ELT--EINLDATGSQKFPQCLCSGCTKKLMGAYCYVKQAMAANELLMKHLKN----GAA---PTS 94
            :||  ::.:|.:|.:.  :||.|             :|.....::::::.:|    |.|   |..
  Rat     3 QLTFRDVAIDFSGEEW--ECLNS-------------EQQNLYTDVMLENYRNLVFLGLAVSKPYL 52

  Fly    95 TDCLQ----------EAPMEL------------CAEQHVEVKLET----EDEDCG---------- 123
            ..||:          :.|:.|            ..||::....:.    ...|||
  Rat    53 VTCLEQRKEPWSVKRQKPVALFPALFPHHNRDFSPEQNINYSFQELIHGPRGDCGFDSLYFPEER 117

  Fly   124 ----ENDVTITCSELPEPDETDMESKKSVDPL-----------TMIETVKLEMEPRSVEKPAYDD 173
                :.|:..||....:|..| .::.||..|.           :.:..|..|....||.|.....
  Rat   118 ELVEDGDILGTCYNRHDPFLT-ADNSKSFTPRRDQEQEMAHKNSQVRQVTSEEPCGSVSKHQNQS 181

  Fly   174 --PTSDFEDEDSLDNLPLYNRIQKWKTGRKSVYKCHDCPRSFKRFDFLKRHEMRVHKPETRLYDC 236
              |||.|:     |||           |.......|.....|..|                  .|
  Rat   182 LKPTSYFK-----DNL-----------GTPQRGLLHSSANDFNNF------------------KC 212

  Fly   237 SLCIRKFSRSEALEAHLKIH-RNSKRSANISEHKKAKAVDLNLCKPHGYKLIECMICQSQYNKIA 300
            |..: .|..:..::..||.. :|||                               |....|.|
  Rat   213 SFGL-SFHSNIFVDGELKNKGKNSK-------------------------------CNQFENSI- 244

  Fly   301 DLRRHLEEHPDIVSLCGRPNMEPHELAELFYP------DSKDLSEEQLINLIRKDLAAGIYQRFY 359
             :...|..:..|...|.:....|.......:|      .|.|:.|   |..|.|:...|..:. .
  Rat   245 -MENSLVYNQQIGLSCAKAQNSPKYGRFFTHPISPSQNSSTDILE---IQYICKENRKGFAEE-S 304

  Fly   360 SITNQSGY---EMDLDSSETDSDL-----DGDHDDQHKRRKKSRKATYSCELCQQKFPRKYQLYD 416
            :::|:.|.   |.....:|.:|||     ..:|...|         .|.|..|...|.:..:|..
  Rat   305 TLSNRQGMYIAETVYQGNENNSDLALESYPANHQSAH---------LYKCYKCDTAFHQYSELII 360

  Fly   417 H-----QRQSHSWSDAPHVCGRCDGRFVSLQLLRHHNESQCRN--AQKRFLCHKCPLRFRWKHNL 474
            |     |.|.....|       |...|       |.:.|..::  .:|.:.|.:|...|.:..:|
  Rat   361 HQYIHIQDQISKGMD-------CSTAF-------HQSSSLTKSHAGEKPYKCKECGKAFTYCSSL 411

  Fly   475 KTHFREHRITNQTFECSECKRVFDKKKSLTVHLLSVHAEESKLIPCQWCSRKFYRHDYLVKHLKR 539
            :.|.|.|....| .:|.:|.:.|..|..||.| .|:||.: |...|::|.:.|.:...:.:|.:.
  Rat   412 RQHHRIHSGVKQ-HKCKDCGKAFYHKSLLTQH-QSIHAGK-KPYCCKFCGKAFNQRSTVTQHQRI 473

  Fly   540 HGLKEHDIPLAETLIAATSRPNGAKRITCRMCNLHFERIVDLRAHIQLELKLSLSLHQSYDSPHN 604
            |                    .|.:...|:.|...|.:            :.||||||...:...
  Rat   474 H--------------------TGERPYHCKDCGKAFHQ------------RSSLSLHQRVHTGEK 506

  Fly   605 YSITNESGFELQLEDSETEDEMQPGVGSRPVYICELCSVQCKRKFEMIQHQRTMHRFDKMPHECD 669
            .....|.|.........|:.: :...|.|| |.|:.|.....:|..:.|||| :|..:| |:.|.
  Rat   507 PYKCKECGKAFNRNSLLTQHQ-RIHTGERP-YHCKDCGKTFNKKSSLTQHQR-IHTGEK-PYSCK 567

  Fly   670 DCIFKCVSKSIMDHHRQGQCSSTEKKHACGKCSYKFMWPENLEQHILLQHSKSSVSNPTGDRHTQ 734
            ||......:|.:..|::|.  :.||.:.|.:|...|.     ....|.||.|.         ||
  Rat   568 DCGKAFNQRSSLSLHQRGH--TGEKPNKCNECGKAFN-----RVFFLTQHQKI---------HT- 615

  Fly   735 GTGDLEKDATEDGIPLLQCPHCDRTYQMKSRLNNHIRDVHINGDRKRKEAIKRFLCSLCGMETRS 799
                        |.....|..|.:.::.:|.|..|.| || .||       |.:.|..||.....
  Rat   616 ------------GEKAYHCKDCGKAFKQRSSLTQHQR-VH-TGD-------KPYHCKHCGKAFTQ 659

  Fly   800 AAALVTHMRRHTGEKPFKCDLCEMAFPRHSELASHRRMHTGEKPFHCTVCGKDFARSDKLKRHML 864
            .::...|.|.||||||:||..|:.||.|:..|..|:|:||||||:||..||:.|.:...|.:|..
  Rat   660 RSSFTRHQRIHTGEKPYKCQDCDKAFSRNLLLIQHQRIHTGEKPYHCQDCGRAFNQRSSLTQHQR 724

  Fly   865 THSGLKPHKCTYCEKSYRQAKDLKLHLQQHTGECPFVCGTCGERFIQSSTLEKHR 919
            .|:|.||..|..|.|::.|......|.:.||||..:.|..|...|..||.|.:|:
  Rat   725 VHTGDKPFCCKDCGKAFTQRSSFNRHQRVHTGEKQYKCKECDRAFKCSSHLAEHQ 779

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18476	NP_731615.1	C2H2 Zn finger	206..227	CDD:275368	3/20 (15%)
		C2H2 Zn finger	236..256	CDD:275368	5/19 (26%)
		C2H2 Zn finger	401..422	CDD:275368	7/25 (28%)
		C2H2 Zn finger	431..447	CDD:275368	2/15 (13%)
		C2H2 Zn finger	461..481	CDD:275368	6/19 (32%)
		C2H2 Zn finger	490..511	CDD:275368	8/20 (40%)
		C2H2 Zn finger	520..540	CDD:275368	4/19 (21%)
		C2H2 Zn finger	638..659	CDD:275368	7/20 (35%)
		C2H2 Zn finger	668..690	CDD:275368	6/21 (29%)
		C2H2 Zn finger	698..715	CDD:275368	3/16 (19%)
		C2H2 Zn finger	753..774	CDD:275368	6/20 (30%)
		C2H2 Zn finger	790..810	CDD:275368	5/19 (26%)
		COG5048	814..>886	CDD:227381	32/71 (45%)
		C2H2 Zn finger	818..838	CDD:275368	8/19 (42%)
		C2H2 Zn finger	846..866	CDD:275368	6/19 (32%)
		C2H2 Zn finger	874..894	CDD:275368	5/19 (26%)
		C2H2 Zn finger	902..924	CDD:275368	7/18 (39%)
Zfp267	NP_001395762.1	KRAB	4..64	CDD:214630	14/74 (19%)
		C2H2 Zn finger	345..364	CDD:275368	5/18 (28%)
		C2H2 Zn finger	375..390	CDD:275368	5/28 (18%)
		C2H2 Zn finger	398..418	CDD:275368	6/19 (32%)
		zf-H2C2_2	410..435	CDD:463886	8/25 (32%)
		C2H2 Zn finger	426..446	CDD:275368	8/20 (40%)
		C2H2 Zn finger	454..474	CDD:275368	4/19 (21%)
		COG5048	<479..633	CDD:227381	46/198 (23%)
		C2H2 Zn finger	482..502	CDD:275368	9/31 (29%)
		C2H2 Zn finger	510..530	CDD:275368	3/20 (15%)
		C2H2 Zn finger	538..558	CDD:275368	7/20 (35%)
		C2H2 Zn finger	566..586	CDD:275368	5/19 (26%)
		C2H2 Zn finger	594..614	CDD:275368	7/33 (21%)
		C2H2 Zn finger	622..642	CDD:275368	6/20 (30%)
		zf-H2C2_2	634..659	CDD:463886	11/33 (33%)
		C2H2 Zn finger	650..670	CDD:275368	5/19 (26%)
		zf-H2C2_2	665..687	CDD:463886	13/21 (62%)
		C2H2 Zn finger	678..698	CDD:275368	8/19 (42%)
		zf-H2C2_2	691..715	CDD:463886	14/23 (61%)
		C2H2 Zn finger	706..726	CDD:275368	6/19 (32%)
		zf-H2C2_2	718..743	CDD:463886	9/24 (38%)
		C2H2 Zn finger	734..754	CDD:275368	5/19 (26%)
		zf-H2C2_2	746..771	CDD:463886	8/24 (33%)
		C2H2 Zn finger	762..779	CDD:275368	6/16 (38%)