DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14715 and FKBP7

DIOPT Version :9

Sequence 1:	NP_650101.1	Gene:	CG14715 / 41403	FlyBaseID:	FBgn0037930	Length:	138	Species:	Drosophila melanogaster
Sequence 2:	NP_851939.1	Gene:	FKBP7 / 51661	HGNCID:	3723	Length:	222	Species:	Homo sapiens

Alignment Length:	120	Identity:	55/120 - (45%)
Similarity:	74/120 - (61%)	Gaps:	5/120 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 SDPKVKIGIKKRVENCTRKAKGGDLVHVHYRGAL-QDGTEF--DSSYSRGTPFSFTLGARQVIKG 80
            |..:|||.:..|.|||::.:|.|||::.||.|.| :||::|  ..:.:.|.|..|.||..|||||
Human    31 STEEVKIEVLHRPENCSKTSKKGDLLNAHYDGYLAKDGSKFYCSRTQNEGHPKWFVLGVGQVIKG 95

  Fly    81 WDQGILGMCEGEQRKLTIPPELGYGASGAGGGKIPPNAVLVFDTELVKIE--PRS 133
            .|..:..||.||:||:.|||...||..|...|||||:|.|:|:.||..:.  |||
Human    96 LDIAMTDMCPGEKRKVVIPPSFAYGKEGYAEGKIPPDATLIFEIELYAVTKGPRS 150

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14715	NP_650101.1	FKBP_C	34..127	CDD:278674	44/95 (46%)
FKBP7	NP_851939.1	FKBP_C	46..141	CDD:306713	43/94 (46%)
		EF-hand_7	152..214	CDD:316058
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	200..222
		Retention in the endoplasmic reticulum. /evidence=ECO:0000255\|PROSITE-ProRule:PRU10138	219..222
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0545
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1507309at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820