DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14715 and fkbp5

DIOPT Version :9

Sequence 1:	NP_650101.1	Gene:	CG14715 / 41403	FlyBaseID:	FBgn0037930	Length:	138	Species:	Drosophila melanogaster
Sequence 2:	XP_005166078.1	Gene:	fkbp5 / 368924	ZFINID:	ZDB-GENE-030616-630	Length:	477	Species:	Danio rerio

Alignment Length:	132	Identity:	51/132 - (38%)
Similarity:	67/132 - (50%)	Gaps:	12/132 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 FVAASAASDPKVKIGIKKRVENCTRKAKG-----GDLVHVHYRGALQDGTEFDSSYSRGTPFSFT 71
            |.:...|..|....|:.|.|:.  ...:|     ||.|.|||.|.|..|.:||||..|..||.|.
Zfish    42 FTSRGTAVTPNGDSGVCKIVKQ--HGVEGERPMIGDRVFVHYTGRLLSGKKFDSSLDRKEPFVFN 104

  Fly    72 LGARQVIKGWDQGILGMCEGEQRKLTIPPELGYGASGAGGGKIPPNAVLVFDTELVKIEPRSGSE 136
            :|..||||.||..:..|.:||...:...||..||::|: ..|:|||:.|||:.||:...    .|
Zfish   105 VGKGQVIKAWDICVCSMQKGEVCLMLCKPEYAYGSAGS-PPKVPPNSTLVFEIELLNFR----GE 164

  Fly   137 EL 138
            ||
Zfish   165 EL 166

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14715	NP_650101.1	FKBP_C	34..127	CDD:278674	41/97 (42%)
fkbp5	XP_005166078.1	FKBP_C	69..159	CDD:278674	40/90 (44%)
		FkpA	<167..271	CDD:223619	51/132 (39%)
		TPR_11	291..372	CDD:290150
		TPR repeat	292..320	CDD:276809
		TPR repeat	340..370	CDD:276809
		TPR_11	343..405	CDD:290150
		TPR	343..374	CDD:197478
		TPR repeat	375..403	CDD:276809
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0545
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810