DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG14715 and FKBP15

DIOPT Version :10

Sequence 1:NP_650101.1 Gene:CG14715 / 41403 FlyBaseID:FBgn0037930 Length:138 Species:Drosophila melanogaster
Sequence 2:NP_056073.1 Gene:FKBP15 / 23307 HGNCID:23397 Length:1219 Species:Homo sapiens


Alignment Length:102 Identity:38/102 - (37%)
Similarity:56/102 - (54%) Gaps:6/102 - (5%)


- Green bases have known domain annotations that are detailed below.


  Fly    41 GDLVHVHYRGALQD----GTEFDSSYSRGTPFSFTLGARQVIKGWDQGILGMCEGEQRKLTIPPE 101
            ||.:.|.|.|.|..    |..|||:.::.......||:.:|||||:.|:|||.:|.:|.|.:||.
Human   197 GDSLEVAYTGWLFQNHVLGQVFDSTANKDKLLRLKLGSGKVIKGWEDGMLGMKKGGKRLLIVPPA 261

  Fly   102 LGYGASGAGGGKIPPNAVLVFDTEL--VKIEPRSGSE 136
            ...|:.|..|.....:::|||:.|:  ||....|||:
Human   262 CAVGSEGVIGWTQATDSILVFEVEVRRVKFARDSGSD 298

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG14715NP_650101.1 FKBP_C 34..127 CDD:459735 33/91 (36%)
FKBP15NP_056073.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 41..66
PH-like 70..168 CDD:473070
Important for function in growth cone organization. /evidence=ECO:0000250 72..169
FKBP_C 193..286 CDD:459735 32/88 (36%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 294..349 3/5 (60%)
Atrophin-1 307..>495 CDD:460830
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 381..433
FAM184 514..710 CDD:464788
Smc <620..>882 CDD:440809
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 739..761
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 931..1219
PHA03247 <951..1164 CDD:223021
Blue background indicates that the domain is not in the aligned region.

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