DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14715 and Fkbp14

DIOPT Version :9

Sequence 1:	NP_650101.1	Gene:	CG14715 / 41403	FlyBaseID:	FBgn0037930	Length:	138	Species:	Drosophila melanogaster
Sequence 2:	NP_705801.1	Gene:	Fkbp14 / 231997	MGIID:	2387639	Length:	211	Species:	Mus musculus

Alignment Length:	134	Identity:	66/134 - (49%)
Similarity:	90/134 - (67%)	Gaps:	8/134 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 ILLICAFVAASA-ASDPKVKIGIKKRVENCTRKAKGGDLVHVHYRGALQ-DGTEFDSS--YSRGT 66
            ||.:...|.:.| ..:|:|||.:.::...|.||.|||||:.|||.|.|: ||:.|.|:  ::.|.
Mouse     9 ILALWVTVLSGALIPEPEVKIEVLQKPFICHRKTKGGDLMLVHYEGYLEKDGSLFHSTHKHNNGQ 73

  Fly    67 PFSFTLGARQVIKGWDQGILGMCEGEQRKLTIPPELGYGASGAGGGKIPPNAVLVFDTELVKIE- 130
            |..||||..:|:||||||:.|||.||:||||:||.||||..|.  |||||.:.|:|:.:|::|.
Mouse    74 PVWFTLGILEVLKGWDQGLKGMCVGEKRKLTVPPALGYGKEGK--GKIPPESTLIFNIDLLEIRN 136

  Fly   131 -PRS 133
             |||
Mouse   137 GPRS 140

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14715	NP_650101.1	FKBP_C	34..127	CDD:278674	53/95 (56%)
Fkbp14	NP_705801.1	FKBP_C	38..132	CDD:278674	53/95 (56%)
		EF-hand_7	141..204	CDD:290234	66/134 (49%)
		EFh	142..204	CDD:298682
		Prevents secretion from ER. /evidence=ECO:0000255\|PROSITE-ProRule:PRU10138	208..211
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0545
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1507309at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101705
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.720