DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14715 and Fkbp4

DIOPT Version :9

Sequence 1:	NP_650101.1	Gene:	CG14715 / 41403	FlyBaseID:	FBgn0037930	Length:	138	Species:	Drosophila melanogaster
Sequence 2:	NP_034349.1	Gene:	Fkbp4 / 14228	MGIID:	95543	Length:	458	Species:	Mus musculus

Alignment Length:	123	Identity:	55/123 - (44%)
Similarity:	69/123 - (56%)	Gaps:	10/123 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 PKVKIGIKKRVENCTRKAKG------GDLVHVHYRGALQDGTEFDSSYSRGTPFSFTLGARQVIK 79
            ||...|:.|.::   |:..|      ||.|.|||.|.|.|||:||||..|...|||.||..:|||
Mouse    27 PKQDEGVLKVIK---REGTGTETPMIGDRVFVHYTGWLLDGTKFDSSLDRKDKFSFDLGKGEVIK 88

  Fly    80 GWDQGILGMCEGEQRKLTIPPELGYGASGAGGGKIPPNAVLVFDTELVKIEPRSGSEE 137
            .||..:..|..||...:|..||..|||:|: ..||||||.|||:.||.:.:....:||
Mouse    89 AWDIAVATMKVGEVCHITCKPEYAYGAAGS-PPKIPPNATLVFEVELFEFKGEDLTEE 145

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14715	NP_650101.1	FKBP_C	34..127	CDD:278674	48/98 (49%)
Fkbp4	NP_034349.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..24
		FKBP_C	43..134	CDD:278674	46/91 (51%)
		Interaction with tubulin. /evidence=ECO:0000250	267..400
		TPR_11	274..349	CDD:290150
		TPR repeat	274..301	CDD:276809
		TPR repeat	306..348	CDD:276809
		TPR_1	321..352	CDD:278916
		TPR_11	322..384	CDD:290150
		TPR repeat	353..381	CDD:276809
		TPR_1	354..386	CDD:278916
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	428..458
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0545
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810