DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14715 and FKBP9

DIOPT Version :9

Sequence 1:	NP_650101.1	Gene:	CG14715 / 41403	FlyBaseID:	FBgn0037930	Length:	138	Species:	Drosophila melanogaster
Sequence 2:	NP_001271270.1	Gene:	FKBP9 / 11328	HGNCID:	3725	Length:	623	Species:	Homo sapiens

Alignment Length:	125	Identity:	58/125 - (46%)
Similarity:	75/125 - (60%)	Gaps:	4/125 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 VAASAASDPKVKIGIKKRV--ENCTRKAKGGDLVHVHYRGALQDGTEFDSSYSRGTPFSFTLGAR 75
            ||.....:||..|.|:.:|  |||.|.::.||.:..||.|.|.|||.|||||||...|...:|..
Human   301 VALLDLHNPKDSISIENKVVPENCERISQSGDFLRYHYNGTLLDGTLFDSSYSRNRTFDTYIGQG 365

  Fly    76 QVIKGWDQGILGMCEGEQRKLTIPPELGYGASGAGGGKIPPNAVLVFDTELVKIEPRSGS 135
            .||.|.|:|:||:|.||:|::.:||.||||..|.  |.||.:||||||..::.....|.|
Human   366 YVIPGMDEGLLGVCIGEKRRIVVPPHLGYGEEGR--GNIPGSAVLVFDIHVIDFHNPSDS 423

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14715	NP_650101.1	FKBP_C	34..127	CDD:278674	47/92 (51%)
FKBP9	NP_001271270.1	FKBP_C	47..191	CDD:278674
		FKBP_C	212..304	CDD:278674	2/2 (100%)
		FKBP_C	324..415	CDD:278674	47/92 (51%)
		FKBP_C	435..527	CDD:278674
		EF-hand_7	548..612	CDD:290234
		EFh	550..611	CDD:238008
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0545
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1507309at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820