Protein Alignment CG42327 and PTPN5

DIOPT Version :9

• Sequence 1: NP_001036706.2
• Gene: CG42327 / 41401
• FlyBaseID: FBgn0259227
• Length: 1429
• Species: Drosophila melanogaster
• Sequence 2: XP_016873923.1
• Gene: PTPN5 / 84867
• HGNCID: 9657
• Length: 719
• Species: Homo sapiens
• Alignment Length: 462
• Identity: 111/462 - (24%)
• Similarity: 177/462 - (38%)
• Gaps: 124/462 - (26%)

  Fly   928 QPVEISLLDDS---TTTTTTTPAPPVYFESSTVA-----------STTIRSSTTMLPETTTASTQ 978
            ||:.:..||::   ..:....|.||.....|..|           |.|:|||..:.     |::|
Human    36 QPIVMEALDEAEGLQDSQREMPPPPPPSPPSDPAQKPPPRGAGSHSLTVRSSLCLF-----AASQ 95

  Fly   979 SPSEMPPTFMAPYPNELDHMQTNA----------------QDNGT-DVNVIIAITVSVIGVVALI 1026
            ........:.:.|.:......||.                .|:|| .|..::.:.:|| |:|.:.
Human    96 FLLACGVLWFSGYGHIWSQNATNLVSSLLTLLKQLEPTAWLDSGTWGVPSLLLVFLSV-GLVLVT 159

  Fly  1027 LLVAFLYLMR------------------KRQKQTSYGQ--------------------------- 1046
            .||  .:|:|                  .||...:|.:
Human   160 TLV--WHLLRTPPEPPTPLPPEDRRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPETPVFDCVMD 222

  Fly  1047 ---RCRPVSLDAYSLDNVSVLGSVRRKGRDMR---------ASKRTYGNAAFD-DPSLRHNLLTA 1098
               ...|.||      .|..:|...|:|.::.         .::..:|..... :.|.|..||:|
Human   223 IKPEADPTSL------TVKSMGLQERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSA 281

  Fly  1099 SELAR---FVERRSDVF---EEFRDVPQIIARADEVP-PGCEDKNRYANVIPLPETRVVLQRQGD 1156
            |.:.:   ..|:..|.|   .||.::|.......|.. ||...||||..::|.|.:||.|.....
Human   282 SRVLQAEELHEKALDPFLLQAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDP 346

  Fly  1157 DDK-TEYINANYVRGPRDAPNYYIACQAPLESTTSDFWRMIWEQQSRVIIQATDLSENGIERCAE 1220
            ||. :.||||||:||.......|||.|.|:.||.:|||||:|::.:.:|:..|::.|.. |:|.|
Human   347 DDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMN-EKCTE 410

  Fly  1221 YLPPSATLDNHSSYGDYQVTLKHREVKDRYAISTLVLKRVDGEESRELTHYWYKWPEA------G 1279
            |.|     :...:|...::|::.....:.|.:..:.||..|.|: |.|..:.:..|.|      |
Human   411 YWP-----EEQVAYDGVEITVQKVIHTEDYRLRLISLKCRDWED-RLLHCHQHLLPAAAAGGCGG 469

  Fly  1280 VPAEEAP 1286
            .|.:..|
Human   470 HPEDHVP 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42327	NP_001036706.2	PTPc	1134..1415	CDD:238006	54/160 (34%)
		Y_phosphatase	1134..1415	CDD:278528	54/160 (34%)
PTPN5	XP_016873923.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0789
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D566624at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910