Protein Alignment CG42327 and PTPN7

DIOPT Version :9

• Sequence 1: NP_001036706.2
• Gene: CG42327 / 41401
• FlyBaseID: FBgn0259227
• Length: 1429
• Species: Drosophila melanogaster
• Sequence 2: XP_011508121.1
• Gene: PTPN7 / 5778
• HGNCID: 9659
• Length: 511
• Species: Homo sapiens
• Alignment Length: 418
• Identity: 103/418 - (24%)
• Similarity: 162/418 - (38%)
• Gaps: 115/418 - (27%)

  Fly  1053 LDAYSLDNVSVLGSVRRKGRDMRASKRTYGNAAFDDPSLRHNLLTASELARFVERRSDVFEEFRD 1117
            ||..||..|..:.||...........||.|:.           ||...|.|.......:.|||..
Human   155 LDVRSLGAVEPICSVNTPREVTLHFLRTAGHP-----------LTRWALQRQPPSPKQLEEEFLK 208

  Fly  1118 VPQIIARADEVP-PGCEDKNRYANVIPLPETRVVLQRQGDDDKTEYINANYVRGPRDAPNYYIAC 1181
            :|......:::. ||...|:||..::|.|::||.|.|....:..:||||||:||.......|||.
Human   209 IPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIAT 273

  Fly  1182 QAPLESTTSDFWRMIWEQQSRVIIQATDLSENGIERCAEYLPPSATLDNHSSYGDYQVTLKHREV 1246
            |.|:.:|.||||.|:|:::..:|:..|.|.| |.|:|..|.|     ....:||.:|:.::..:.
Human   274 QGPMPNTVSDFWEMVWQEEVSLIVMLTQLRE-GKEKCVHYWP-----TEEETYGPFQIRIQDMKE 332

  Fly  1247 KDRYAISTLVLKRVDGEESRELTHYWYK-WPEAGVPAEEAPIIAMLLEARSSLKSYSLEQANELR 1310
            ...|.:..|.::.  .||.|.:.|..:. ||:...|....|::.::.|..
Human   333 CPEYTVRQLTIQY--QEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVE--------------- 380

  Fly  1311 EKSATLETSMDADGSKAEAGSTSSHEINGNISSRSGTRSQQGPLTVHCSPGTGRTGTIIASDMAI 1375
                             |:..|::|               .||:.||||.|.||||..||:.:..
Human   381 -----------------ESPETAAH---------------PGPIVVHCSAGIGRTGCFIATRIGC 413

  Fly  1376 RSLETPKRSVDIPQLVYYVRRGR------------------------------------------ 1398
            :.|:. :..|||..:|..:|..|
Human   414 QQLKA-RGEVDILGIVCQLRLDRLLERRKLEAQEYSWPDPRLQRSGFVPGAEWIKEDQVSTWGIT 477

  Fly  1399 ----ASAVQTKEQYEFIYKVASMYAAKI 1422
                ...:||.|||:|::...::||.::
Human   478 PQHVGGMIQTAEQYQFLHHTLALYAGQL 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42327	NP_001036706.2	PTPc	1134..1415	CDD:238006	81/327 (25%)
		Y_phosphatase	1134..1415	CDD:278528	81/327 (25%)
PTPN7	XP_011508121.1	PTPc	201..499	CDD:214550	87/353 (25%)
		PTPc	227..499	CDD:238006	81/327 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0789
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D566624at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910