Protein Alignment CG42327 and ptprga

DIOPT Version :10

• Sequence 1: NP_001036706.2
• Gene: CG42327 / 41401
• FlyBaseID: FBgn0259227
• Length: 1429
• Species: Drosophila melanogaster
• Sequence 2: NP_001316793.1
• Gene: ptprga / 561197
• ZFINID: ZDB-GENE-101101-4
• Length: 1414
• Species: Danio rerio
• Alignment Length: 904
• Identity: 207/904 - (22%)
• Similarity: 329/904 - (36%)
• Gaps: 284/904 - (31%)

  Fly   668 SNIRDDNDDNSNDVIVATTK--------FPESEQAATTASVEPTTTSVSVRVAGEVSTSI----- 719
            :|.|.....::.:|..:..|        :|......|.||...::..:::.|.....|::
Zfish   304 NNFRPLQSLDNREVFKSAVKDAWLPDLTYPPGNPYGTEASKACSSAPINMNVQHMNKTALVVRWS 368

  Fly   720 RPEI-----IVTS------TRNSTIVDTSTSAT----------SVATPTQTEI------------ 751
            ||||     |::.      |||    |.|...|          :|.||...::
Zfish   369 RPEITYDPPIISYLISYSWTRN----DESYEETYFKGSDQKLEAVITPVSPDVLYLFRVQAVCLN 429

  Fly   752 ---AQISNEVNLEAVTVKTRDGLSDTNELRT-------AEKTDNA------------------VN 788
               :..|..:...|.|.:..:|   |..::|       |...|.|                  |:
Zfish   430 DKRSDFSQSMLFRANTTRIFEG---TRIVKTGMPTVSPASSADMAPISSGSSTWTSSGLPFSFVS 491

  Fly   789 NSVAITESDLGALATAVETNPTTTNSLLSDV----SKLSKEHESSLETNNIGEAPPESTTPA--- 846
            .:..|..|..|:.||...   ..|::||:.:    ..:|....|...|    ..||.|..||
Zfish   492 MATGIGPSSSGSQATVAS---VVTSTLLAGLGFSGGVISSFPSSVWPT----RPPPSSPAPASTH 549

  Fly   847 -APATVAVATDESTAAPAAT---------GGQEIVREGQHHDGQQVADEQDTEQQLAKTTMAVTT 901
             :||...|.|.|..:....|         .|.|...:|:..||::..:|::.|.:   .....:.
Zfish   550 QSPAKPVVTTAEQASDADTTTATDNDRSDDGGEKGGKGEDEDGEKNGEEEEDEDE---EKGGESK 611

  Fly   902 TTTSATTTTTSTTTTTTETPLTTTTMQPVEISLLDDSTT-------TTTTTPAPPVYFESSTVA- 958
            .:.:.......|.::.::.|.|.          :.|||.       .|..:.||....|.:|..
Zfish   612 DSRAPDDVEKQTNSSVSKDPPTA----------VPDSTAKEKGGRRRTENSTAPSRVSEENTQGL 666

  Fly   959 ----STTIRSSTTMLPETTTASTQSPSEMPPTFMAPYPNELDHMQTNAQDNGTDVN--------- 1010
                :..:.|....:.|..||..::|               ::.:.:::||..|.|
Zfish   667 GEENTQVMASREPEVEENVTAVIETP---------------ENTEQSSKDNRGDRNHLPPFSIHT 716

  Fly  1011 -------------------VIIAITVSVIGVVALILLVAFLYLMRKRQKQTSYGQRCRPVSLDAY 1056
                               :|..:.||.:..:.||||:|.|.          |.:||...: ..|
Zfish   717 ERTVVSSMYPGPAAGRMEWIIPLVVVSALTFLCLILLLAVLV----------YWRRCFQTA-HFY 770

  Fly  1057 SLDNVSVLGSVRRKGRDMRASKRTYGNAAF------DDPS---LRHNLLTASELARFVERRSDVF 1112
            ..|:               .|.|...|.:.      ||..   ::|.:...|||  :...:....
Zfish   771 VEDS---------------NSPRVVPNESIPVIPIPDDMEAIPVKHFIKHVSEL--YSNNQHGFS 818

  Fly  1113 EEFRDVPQI-----IARADEVPPGCEDKNRYANVIPLPETRVVLQ-RQGDDDK-TEYINANYVRG 1170
            ::|.:|.:.     |.......|..:.||||.|:|....:||.|: ..|.|.| ::|||||||.|
Zfish   819 DDFEEVQRCTADMKITAEHSNHPDNKHKNRYINIIAYDHSRVKLRPLAGKDSKHSDYINANYVDG 883

  Fly  1171 PRDAPNYYIACQAPLESTTSDFWRMIWEQQSRVIIQATDLSENGIERCAEYLPPSATLDNHSSYG 1235
             .:.|..|||.|.||:||..|||||:|||.:.:|:..|:|.|.|..:|.:|.|.    :|...||
Zfish   884 -YNKPKAYIAAQGPLKSTFEDFWRMVWEQNTGIIVMITNLVEKGRRKCDQYWPS----ENSEEYG 943

  Fly  1236 DYQVTLKHREVKDRYAI------STLVLKRVDG-----EESRELTHYWY-KWPEAGVPAEEAPII 1288
            :..||||..:|...|.:      :|.|.|...|     :..|.:..|.| :||:.|||....|::
Zfish   944 NIVVTLKRTKVMACYTLRIFTIRNTKVKKGQKGNTKGRQSERTVLQYHYTQWPDMGVPEYTLPVL 1008

  Fly  1289 AMLLEARSSLKSYSLEQANELREKSATLETSMDADGSKAEAGSTSSHEINGNISSRSGTRSQQGP 1353
            ..:                   .||:..:|                              ...||
Zfish  1009 TFV-------------------RKSSAAQT------------------------------PDMGP 1024

  Fly  1354 LTVHCSPGTGRTGTIIASDMAIRSLETPKRSVDIPQLVYYVRRGRASAVQTKEQYEFIY 1412
            :.||||.|.|||||.|..|..::.|: .|.:|::...:.::|..|...|||:|||.||:
Zfish  1025 MLVHCSAGVGRTGTYIVIDSMLQQLK-DKGAVNVLGFLKHIRTQRNYLVQTEEQYIFIH 1082

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42327	NP_001036706.2	PTPc	1134..1415	CDD:214550	97/293 (33%)
ptprga	NP_001316793.1	alpha_CARP_receptor_like	71..319	CDD:239396	3/14 (21%)
		FN3	348..426	CDD:214495	16/81 (20%)
		R-PTPc-G-1	817..1090	CDD:350505	101/321 (31%)
		R-PTP-G-2	1174..1378	CDD:350508