DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42327 and ptprga

DIOPT Version :9

Sequence 1:	NP_001036706.2	Gene:	CG42327 / 41401	FlyBaseID:	FBgn0259227	Length:	1429	Species:	Drosophila melanogaster
Sequence 2:	NP_001316793.1	Gene:	ptprga / 561197	ZFINID:	ZDB-GENE-101101-4	Length:	1414	Species:	Danio rerio

Alignment Length:	904	Identity:	207/904 - (22%)
Similarity:	329/904 - (36%)	Gaps:	284/904 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   668 SNIRDDNDDNSNDVIVATTK--------FPESEQAATTASVEPTTTSVSVRVAGEVSTSI----- 719
            :|.|.....::.:|..:..|        :|......|.||...::..:::.|.....|::
Zfish   304 NNFRPLQSLDNREVFKSAVKDAWLPDLTYPPGNPYGTEASKACSSAPINMNVQHMNKTALVVRWS 368

  Fly   720 RPEI-----IVTS------TRNSTIVDTSTSAT----------SVATPTQTEI------------ 751
            ||||     |::.      |||    |.|...|          :|.||...::
Zfish   369 RPEITYDPPIISYLISYSWTRN----DESYEETYFKGSDQKLEAVITPVSPDVLYLFRVQAVCLN 429

  Fly   752 ---AQISNEVNLEAVTVKTRDGLSDTNELRT-------AEKTDNA------------------VN 788
               :..|..:...|.|.:..:|   |..::|       |...|.|                  |:
Zfish   430 DKRSDFSQSMLFRANTTRIFEG---TRIVKTGMPTVSPASSADMAPISSGSSTWTSSGLPFSFVS 491

  Fly   789 NSVAITESDLGALATAVETNPTTTNSLLSDV----SKLSKEHESSLETNNIGEAPPESTTPA--- 846
            .:..|..|..|:.||...   ..|::||:.:    ..:|....|...|    ..||.|..||
Zfish   492 MATGIGPSSSGSQATVAS---VVTSTLLAGLGFSGGVISSFPSSVWPT----RPPPSSPAPASTH 549

  Fly   847 -APATVAVATDESTAAPAAT---------GGQEIVREGQHHDGQQVADEQDTEQQLAKTTMAVTT 901
             :||...|.|.|..:....|         .|.|...:|:..||::..:|::.|.:   .....:.
Zfish   550 QSPAKPVVTTAEQASDADTTTATDNDRSDDGGEKGGKGEDEDGEKNGEEEEDEDE---EKGGESK 611

  Fly   902 TTTSATTTTTSTTTTTTETPLTTTTMQPVEISLLDDSTT-------TTTTTPAPPVYFESSTVA- 958
            .:.:.......|.::.::.|.|.          :.|||.       .|..:.||....|.:|..
Zfish   612 DSRAPDDVEKQTNSSVSKDPPTA----------VPDSTAKEKGGRRRTENSTAPSRVSEENTQGL 666

  Fly   959 ----STTIRSSTTMLPETTTASTQSPSEMPPTFMAPYPNELDHMQTNAQDNGTDVN--------- 1010
                :..:.|....:.|..||..::|               ::.:.:::||..|.|
Zfish   667 GEENTQVMASREPEVEENVTAVIETP---------------ENTEQSSKDNRGDRNHLPPFSIHT 716

  Fly  1011 -------------------VIIAITVSVIGVVALILLVAFLYLMRKRQKQTSYGQRCRPVSLDAY 1056
                               :|..:.||.:..:.||||:|.|.          |.:||...: ..|
Zfish   717 ERTVVSSMYPGPAAGRMEWIIPLVVVSALTFLCLILLLAVLV----------YWRRCFQTA-HFY 770

  Fly  1057 SLDNVSVLGSVRRKGRDMRASKRTYGNAAF------DDPS---LRHNLLTASELARFVERRSDVF 1112
            ..|:               .|.|...|.:.      ||..   ::|.:...|||  :...:....
Zfish   771 VEDS---------------NSPRVVPNESIPVIPIPDDMEAIPVKHFIKHVSEL--YSNNQHGFS 818

  Fly  1113 EEFRDVPQI-----IARADEVPPGCEDKNRYANVIPLPETRVVLQ-RQGDDDK-TEYINANYVRG 1170
            ::|.:|.:.     |.......|..:.||||.|:|....:||.|: ..|.|.| ::|||||||.|
Zfish   819 DDFEEVQRCTADMKITAEHSNHPDNKHKNRYINIIAYDHSRVKLRPLAGKDSKHSDYINANYVDG 883

  Fly  1171 PRDAPNYYIACQAPLESTTSDFWRMIWEQQSRVIIQATDLSENGIERCAEYLPPSATLDNHSSYG 1235
             .:.|..|||.|.||:||..|||||:|||.:.:|:..|:|.|.|..:|.:|.|.    :|...||
Zfish   884 -YNKPKAYIAAQGPLKSTFEDFWRMVWEQNTGIIVMITNLVEKGRRKCDQYWPS----ENSEEYG 943

  Fly  1236 DYQVTLKHREVKDRYAI------STLVLKRVDG-----EESRELTHYWY-KWPEAGVPAEEAPII 1288
            :..||||..:|...|.:      :|.|.|...|     :..|.:..|.| :||:.|||....|::
Zfish   944 NIVVTLKRTKVMACYTLRIFTIRNTKVKKGQKGNTKGRQSERTVLQYHYTQWPDMGVPEYTLPVL 1008

  Fly  1289 AMLLEARSSLKSYSLEQANELREKSATLETSMDADGSKAEAGSTSSHEINGNISSRSGTRSQQGP 1353
            ..:                   .||:..:|                              ...||
Zfish  1009 TFV-------------------RKSSAAQT------------------------------PDMGP 1024

  Fly  1354 LTVHCSPGTGRTGTIIASDMAIRSLETPKRSVDIPQLVYYVRRGRASAVQTKEQYEFIY 1412
            :.||||.|.|||||.|..|..::.|: .|.:|::...:.::|..|...|||:|||.||:
Zfish  1025 MLVHCSAGVGRTGTYIVIDSMLQQLK-DKGAVNVLGFLKHIRTQRNYLVQTEEQYIFIH 1082

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42327	NP_001036706.2	PTPc	1134..1415	CDD:238006	97/293 (33%)
CG42327	NP_001036706.2	Y_phosphatase	1134..1415	CDD:278528	97/293 (33%)
ptprga	NP_001316793.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0789
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900