DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42327 and Ptp36E

DIOPT Version :9

Sequence 1:	NP_001036706.2	Gene:	CG42327 / 41401	FlyBaseID:	FBgn0259227	Length:	1429	Species:	Drosophila melanogaster
Sequence 2:	NP_001286033.1	Gene:	Ptp36E / 35091	FlyBaseID:	FBgn0267486	Length:	682	Species:	Drosophila melanogaster

Alignment Length:	383	Identity:	94/383 - (24%)
Similarity:	155/383 - (40%)	Gaps:	100/383 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly  1061 VSVLGS-------VRRKGRDMRAS-KRTYGNAAFDDPSLRHNLLTASELARFVERRSDVFE--EF 1115
            :|:|.|       ::.:.||...| .:|..|...|   :||.|....     :.|:..|..  ||
  Fly    50 LSMLNSGLLSFERIKLEARDENNSLSKTIPNGPID---IRHFLKLCD-----LRRKFPVLYKLEF 106

  Fly  1116 RDVPQIIARADEVPPGCE--------DKNRYANVIPLPETRVVLQRQGDDDKTEYINANYVRGPR 1172
            :...::.:..      |.        :||:....||....||||::.|....::|:||:||
  Fly   107 QTAAKVESNT------CRHALKKNNLEKNQNPKCIPYDYNRVVLEKVGGLQDSDYVNASYV---- 161

  Fly  1173 DA---PNYYIACQAPLESTTSDFWRMIWEQQSRVIIQATDLSENGIERCAEYLPPSATLDNHSSY 1234
            |:   ||.||..|.|:|.|...:|||:|::....|:..|...:.....|.:|.||:  ::.|..|
  Fly   162 DSLLKPNAYIVTQGPVEETVQAYWRMVWQENISAIVMLTKTFDFAKVMCHQYWPPN--MEVHEQY 224

  Fly  1235 GDYQVTLKHREVKDRYAISTLVLKRVDGEESRELT--------HY--WYKWPEAGVPAEEAPIIA 1289
            ||..:.:...|....:.|.|..|.:::  |.:|:|        ||  ||        :...|...
  Fly   225 GDIFINIVREEQLANFHIRTFRLYKMN--EKQEVTDERLILQFHYTEWY--------SHSCPFSN 279

  Fly  1290 MLLEARSSLKSYSLEQANELREKSATLETSMDADGSKAEAGSTSSHEINGNISSRSGTRSQQGPL 1354
            .|||.|..::   |...|.::::.                                   ..:||:
  Fly   280 ALLEFRRRVR---LVVGNIIKDED-----------------------------------DMRGPI 306

  Fly  1355 TVHCSPGTGRTGTIIASDMAIRSLETPKRSVDIPQLVYYVRRGRASAVQTKEQYEFIY 1412
            .||||.|.||:|..::.| |...|...:...::...:..:|:.|...|:..|||:|||
  Fly   307 LVHCSDGGGRSGVYMSID-ANLELAEEEECFNVFGYLKKLRQSRKGLVENVEQYKFIY 363

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42327	NP_001036706.2	PTPc	1134..1415	CDD:238006	77/292 (26%)
CG42327	NP_001036706.2	Y_phosphatase	1134..1415	CDD:278528	77/292 (26%)
Ptp36E	NP_001286033.1	Y_phosphatase	125..368	CDD:395053	77/294 (26%)
Ptp36E	NP_001286033.1	Y_phosphatase	428..671	CDD:395053
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR19134
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100