Protein Alignment CG42327 and Ptpn20

DIOPT Version :9

• Sequence 1: NP_001036706.2
• Gene: CG42327 / 41401
• FlyBaseID: FBgn0259227
• Length: 1429
• Species: Drosophila melanogaster
• Sequence 2: NP_001073618.1
• Gene: Ptpn20 / 306281
• RGDID: 1309812
• Length: 421
• Species: Rattus norvegicus
• Alignment Length: 481
• Identity: 116/481 - (24%)
• Similarity: 189/481 - (39%)
• Gaps: 121/481 - (25%)

  Fly   945 TPAPPVYFESSTVASTTIRSSTTMLPETTTASTQSPSEMPPTFMAPYPNELDHMQTNAQDNGTDV 1009
            ||..||:  .:.|.|.::::|..|       |..:..::    :.|.|.|.|:.:|
  Rat    39 TPTKPVF--GNKVNSESVKTSHHM-------SFSNKYDL----VFPEPVESDNDET--------- 81

  Fly  1010 NVIIAITVSVIGVVALILLVAFLYLMRKRQKQTSYGQRCRPVSLDAYSLDNVSVLGSV-RRKGRD 1073
                                  |:.:|      ....|.|..|:|..|......:.:| .....|
  Rat    82 ----------------------LWDVR------DLSHRNRWSSVDPESAGPSKTVSTVLSESSTD 118

  Fly  1074 MRASKRTYGNAAFDDPSLRHNLLTAS--ELARFVERRS--DVFEEFRDVPQIIARADEVPPGCE- 1133
            ...|:|.....|...|.:.::...|:  :..:.::::.  |:..||.::.::|. .|:...|.|
  Rat   119 TAVSERELTQLAQIRPLIFNSSSRAALRDCLKALQKKEELDIIREFLELEEMIP-PDDFKSGYEL 182

  Fly  1134 ---DKNRYANVIPLPETRVVLQRQGDDDKTEYINANYVRGPRDAPNY-YIACQAPLESTTSDFWR 1194
               |||||.:::|...|||.|.:..|     ||||:|:|.......| |||.|.||..|..|||:
  Rat   183 QNRDKNRYRDILPYDSTRVPLGKNKD-----YINASYIRIVNHEEEYFYIATQGPLPDTIEDFWQ 242

  Fly  1195 MIWEQQSRVIIQATDLSENGIERCAEYLPPSATLDNHSSYGDYQVTLKHREVKDRYAISTLVLKR 1259
            |:.|....||...|...|.|:.:|..|.|.|  |.....:..:.|.|::.::...:.|....:.:
  Rat   243 MVLENNCNVIAMITREIEGGVIKCCSYWPVS--LKEPLEFKHFHVLLENFQITQYFVIRIFQIVK 305

  Fly  1260 VDGEESRELTHYWY-KWPEAGVPAEEAPIIAMLLEARSSLKSYSLEQANELREKSATLETSMDAD 1323
            ....:|..:.|..: |||:.|.||.               ..:.::....:|:...|
  Rat   306 KSTGKSHSVKHLQFIKWPDHGTPAS---------------ADFFIKYVRYVRKSHIT-------- 347

  Fly  1324 GSKAEAGSTSSHEINGNISSRSGTRSQQGPLTVHCSPGTGRTGTIIASDMAIRSLETPKRSVDIP 1388
                                        |||.||||.|.||||..|..|:...::| ...|.:|.
  Rat   348 ----------------------------GPLLVHCSAGVGRTGVFICVDVVFCTIE-KNYSFNIM 383

  Fly  1389 QLVYYVRRGRASAVQTKEQYEFIYKV 1414
            .:|..:|:.|...:||||||:|.|::
  Rat   384 NIVTQMRKQRFGMIQTKEQYQFCYEI 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42327	NP_001036706.2	PTPc	1134..1415	CDD:238006	81/283 (29%)
		Y_phosphatase	1134..1415	CDD:278528	81/283 (29%)
Ptpn20	NP_001073618.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..58		6/20 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	93..116		5/22 (23%)
		PTPc	160..412	CDD:214550	87/310 (28%)
		PTPc	186..412	CDD:238006	81/283 (29%)
		Substrate binding. /evidence=ECO:0000250	354..360		3/5 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0789
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900