Protein Alignment CG42327 and Ptpn22

DIOPT Version :9

• Sequence 1: NP_001036706.2
• Gene: CG42327 / 41401
• FlyBaseID: FBgn0259227
• Length: 1429
• Species: Drosophila melanogaster
• Sequence 2: NP_001099930.1
• Gene: Ptpn22 / 295338
• RGDID: 1307992
• Length: 804
• Species: Rattus norvegicus
• Alignment Length: 377
• Identity: 96/377 - (25%)
• Similarity: 159/377 - (42%)
• Gaps: 82/377 - (21%)

  Fly  1058 LDNVSVLGSVRRKGRDMRASKRTYGNAAFDDPSLRHNLLTASELARFVERRSDVFEEFRDVPQII 1122
            :|...:|..:.::.:..:.::..:.|                |..: ::|:|..::..:..|..:
  Rat     1 MDQREILQQLLKEAQKKKINREEFAN----------------EFLK-LKRQSTKYKADKIYPTTV 48

  Fly  1123 ARADEVPPGCEDKNRYANVIPLPETRVVLQRQGDDDKTEYINANYVRGPRDAPNYYIACQAPLES 1187
            |:.    |....||||.:::|...:.|.|.....|:.:.||||::::|.. .|..|||.|.||.:
  Rat    49 AQR----PKNIKKNRYKDILPYDHSLVELSLLTSDEDSSYINASFIKGVY-GPRAYIATQGPLST 108

  Fly  1188 TTSDFWRMIWEQQSRVIIQATDLSENGIERCAEY-LPPSATLDNHSSYGDYQVTLKHREVKDRYA 1251
            |..||||||||.:..||:.|....|.|.::|..| ..|..|   ...:|.:.::.:..:.|..|.
  Rat   109 TLLDFWRMIWEYRVLVIVMACMEFEMGKKKCERYWAEPGET---QLQFGPFSISCETEKKKSDYK 170

  Fly  1252 ISTLVLKRVDGEESRELTHYWYK-WPEAGVPAEEAPIIAMLLEARSSLKSYSLEQANELREKSAT 1315
            |.|  ||.....|:|.:..:.|| ||:..||:...||:.::.:.|.            .:|....
  Rat   171 IRT--LKAKFNSETRIVYQFHYKNWPDHDVPSSIDPILQLIWDMRC------------YQEDDCV 221

  Fly  1316 LETSMDADGSKAEAGSTSSHEINGNISSRSGTRSQQGPLTVHCSPGTGRTGTIIASD---MAIRS 1377
                                                 ||.:|||.|.||||.|.|.|   |.::.
  Rat   222 -------------------------------------PLCIHCSAGCGRTGVICAVDYTWMLLKD 249

  Fly  1378 LETPKRSVDIPQLVYYVRRGRASAVQTKEQYEFIYKVASMYAAKITNLSNDN 1429
            ...|| :..:..|:..:|..|.|.|||:||||.:|........:..::.:||
  Rat   250 GIIPK-NFSVFNLIQEMRTQRPSLVQTQEQYELVYSAVLELFKRHVDIISDN 300

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42327	NP_001036706.2	PTPc	1134..1415	CDD:238006	85/285 (30%)
		Y_phosphatase	1134..1415	CDD:278528	85/285 (30%)
Ptpn22	NP_001099930.1	PTPc	24..288	CDD:214550	92/340 (27%)
		PTPc	56..288	CDD:238006	85/287 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0789
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900