DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42327 and Ptprr

DIOPT Version :9

Sequence 1:	NP_001036706.2	Gene:	CG42327 / 41401	FlyBaseID:	FBgn0259227	Length:	1429	Species:	Drosophila melanogaster
Sequence 2:	NP_035347.1	Gene:	Ptprr / 19279	MGIID:	109559	Length:	656	Species:	Mus musculus

Alignment Length:	386	Identity:	109/386 - (28%)
Similarity:	169/386 - (43%)	Gaps:	69/386 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly  1047 RCRPVSLDAYSLDNVSV------LGSVRRKGRDMRASKRTYGNAAFDDPSLRHNLLTASELARFV 1105
            |.:|:.|......|||:      ||||    ....|........|.:.......:||.|:|...|
Mouse   326 RMKPIGLQERRGSNVSLTLDMSSLGSV----EPFVAVSTPREKVAMEYLQSASRVLTRSQLRDVV 386

  Fly  1106 ERRSDVFEEFRDVPQIIARADEVP-PGCEDKNRYANVIPLPETRVVLQRQG-DDDKTEYINANYV 1168
            .....:..||.::|.......|:. |....||||..::|.|.:||.|:.:. .|..:.||||||:
Mouse   387 ASSHLLQSEFMEIPMNFVDPKEIDIPRHGTKNRYKTILPNPLSRVCLRPKNITDSLSTYINANYI 451

  Fly  1169 RGPRDAPNYYIACQAPLESTTSDFWRMIWEQQSRVIIQATDLSENGIERCAEYLPPSATLDNHSS 1233
            ||.......:||.|.|:.:|.:|||:|:|::.|.||:..|.|.|.. |:|..|.|     :....
Mouse   452 RGYSGKEKAFIATQGPMINTVNDFWQMVWQEDSPVIVMITKLKEKN-EKCVLYWP-----EKRGI 510

  Fly  1234 YGDYQVTLKHREVKDRYAISTLVLKRVDGEESRELTHYWY-KWPEAGVPAEEAPIIAMLLEARSS 1297
            ||..:|.:......|.|.|..||||:  |..::.:.|||| .||:...|....|::.::|:..
Mouse   511 YGKVEVLVTGVTECDNYTIRNLVLKQ--GSHTQHVKHYWYTSWPDHKTPDSAQPLLQLMLDVE-- 571

  Fly  1298 LKSYSLEQANELREKSATLETSMDADGSKAEAGSTSSHEINGNISSRSGTRSQQGPLTVHCSPGT 1362
                               |..:.::|                          :||:.||||.|.
Mouse   572 -------------------EDRLASEG--------------------------RGPVVVHCSAGI 591

  Fly  1363 GRTGTIIASDMAIRSLETPKRSVDIPQLVYYVRRGRASAVQTKEQYEFIYKVASMYAAKIT 1423
            ||||..||:.:..:.|: .:..||...:|..:|..|...|||.|||||::....::.::::
Mouse   592 GRTGCFIATSIGCQQLK-EEGVVDALSIVCQLRVDRGGMVQTSEQYEFVHHALCLFESRLS 651

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42327	NP_001036706.2	PTPc	1134..1415	CDD:238006	87/282 (31%)
CG42327	NP_001036706.2	Y_phosphatase	1134..1415	CDD:278528	87/282 (31%)
Ptprr	NP_035347.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	269..289
		PTPc	391..643	CDD:214550	92/307 (30%)
		PTPc	416..643	CDD:238006	87/282 (31%)
		Substrate binding. /evidence=ECO:0000250	587..593		3/5 (60%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0789
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D566624at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910