DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42327 and Y116A8C.37

DIOPT Version :9

Sequence 1:	NP_001036706.2	Gene:	CG42327 / 41401	FlyBaseID:	FBgn0259227	Length:	1429	Species:	Drosophila melanogaster
Sequence 2:	NP_503038.1	Gene:	Y116A8C.37 / 191006	WormBaseID:	WBGene00013810	Length:	298	Species:	Caenorhabditis elegans

Alignment Length:	395	Identity:	67/395 - (16%)
Similarity:	118/395 - (29%)	Gaps:	173/395 - (43%)

- Green bases have known domain annotations that are detailed below.

  Fly  1058 LDNVSVLGSVRRKGRDMRASKRTYGNAAFDDPSLRHNLLTASELARFVERR------SDVFEE-- 1114
            :|...|...|.|:.|..|..|:                  ..||.:.|:|:      ..::||
Worm     2 IDQFEVNVKVNRRNRQARKVKK------------------VEELGKVVDRKEMDSPLGRLYEEKK 48

  Fly  1115 --------------------------------------FRDVPQIIARADEVP-----------P 1130
                                                  |:.........|..|           |
Worm    49 EERKEEKKEVDKEPWSGEEPAKRMVANGFFTTTNVGGTFKQTDNFKTPMDSCPSFKNNMHKIRAP 113

  Fly  1131 GCEDKNRYANVIPLPETRVVLQRQGDDDKTEYINANYVRGPRDAPNYYIACQAP---LESTTSDF 1192
            .|          |:||.::|....|.:   .:|.|..:..| |.....|..|.|   ....|:||
Worm   114 DC----------PIPEEKLVKLANGPE---SFICAAKITVP-DFNRTMILTQVPDLSRSPDTADF 164

  Fly  1193 WRMIWEQQSRVIIQATDLSENGIERCAEYLPPSATLD--------NHSSYGDYQVTLKHREVKDR 1249
            ||||.::....::.|.             :|...||.        .:|:||  ::.:.:::|:..
Worm   165 WRMIHQESIVSVVIAV-------------MPLEVTLQQILPLLSGTYSTYG--KMFVNNKKVESA 214

  Fly  1250 YAISTLVLKRV-DGEESRELT--HYWYKW-PEAGVPAEEAPIIAMLLEARSSLKSYSLEQANELR 1310
            ..::...|:.: ||..:..||  ::.:.| .:.|            ||..:.|.: ::|:..::.
Worm   215 VGMTEYCLEILPDGCSNSLLTTVYHMHNWRQKRG------------LEVVTDLVT-TMEKVMKVN 266

  Fly  1311 EKSATLETSMDADGSKAEAGSTSSHEINGNISSRSGTRSQQGPLTVHCSPGTGRTGTIIASDMAI 1375
            |.|..:  ||:                                       ||||.|......:..
Worm   267 ENSVLM--SMN---------------------------------------GTGRAGIFQEKPIEF 290

  Fly  1376 RSLET 1380
            |::.|
Worm   291 RNIHT 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42327	NP_001036706.2	PTPc	1134..1415	CDD:238006	49/262 (19%)
CG42327	NP_001036706.2	Y_phosphatase	1134..1415	CDD:278528	49/262 (19%)
Y116A8C.37	NP_503038.1	PTPc	87..283	CDD:214550	52/278 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0789
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900