Protein Alignment CG42327 and K09F6.3

DIOPT Version :10

• Sequence 1: NP_001036706.2
• Gene: CG42327 / 41401
• FlyBaseID: FBgn0259227
• Length: 1429
• Species: Drosophila melanogaster
• Sequence 2: NP_001342012.1
• Gene: K09F6.3 / 173583
• WormBaseID: WBGene00019586
• Length: 1391
• Species: Caenorhabditis elegans
• Alignment Length: 1173
• Identity: 230/1173 - (19%)
• Similarity: 376/1173 - (32%)
• Gaps: 359/1173 - (30%)

  Fly   456 DNVTTARTMPSTPDP------GSMDLNMTTTTVRTQQLEVPLVKKM-SDAANAKLIEAVTEPQRE 513
            |:....|......||      |....|.:.||:   :.:....|.| |:|.|.|.:|.|
 Worm   243 DDFEKIRNPSEFVDPISKIVSGYKKYNASRTTI---ERDGNFAKGMQSNANNMKRLENV------ 298

  Fly   514 TEAATEAATFVTLPEKLATF--GITARVDSTQTELLNVTTAAAATESGEMSKANSTDTLSAMTST 576
                  |:.|    |.|.:|  .:.|.:|..||..|...|......:.:..|
 Worm   299 ------ASVF----EGLGSFVKNLQAVIDVRQTMHLPKYTVGFIDGTFDPKK------------- 340

  Fly   577 TTTTARPMSVEHVTPEQDMEAATSLATTAATSSGTTEAAATSST-----------TAATPVVSEA 630
            ..|......|:.||.|.|:....:|...........||:..||:           ::.|.|....
 Worm   341 VVTDLEDDWVQSVTHEMDLNRTINLLLPIGDHVSAIEASFLSSSSKQSKFFTGFKSSETEVSPVD 405

  Fly   631 ATAAEASATSEATTAATLSVATTAASTTEIAMKATQISNIRDDNDD-----------NSNDVIVA 684
            .:.....:||:..:...::..|...|..|:.:....|.:::...|.           .:|||::
 Worm   406 GSIDSIISTSKKVSECIIAPLTYLESIKEVEILLQAIESLKKTVDTLVGTKELVNWVKTNDVVL- 469

  Fly   685 TTKFPESEQAATTASVEPTTTSVSVRVAGEVSTSIRPEIIVTSTRNSTIVDTSTSATSVATPTQT 749
              |..|:..:.|....:...:||.:::.|..|:.....:|.|..::|...|...|.....|..:|
 Worm   470 --KEVEALCSYTDEEKKDFESSVPIKLKGLKSSENYTSLIKTLNQSSLFADAVFSEKLSTTGQET 532

  Fly   750 -------------------EIAQISNEVN-----LEAVTVKT------------RDGLSDTN--- 775
                               .||.....:|     |..:.:.|            |||:...|
 Worm   533 AYILGGLQSLDAFYNSATDHIAFFDCLLNVAYYDLIPLAIDTLNKVRKMDVQPIRDGIDVVNDLF 597

  Fly   776 -------ELRTAEKTDNAVNNSVAITESDLGALATAVETNPTTTNSLLSDVSKLSKE--HESS-- 829
                   ||:|..:..|..|.|:|.|.....:|.|      ||....:..|.::..|  |.|.
 Worm   598 NVSNQLDELKTKLRELNDPNFSIAETPLSNPSLHT------TTIGLSVRGVIRMKDEIDHRSDFD 656

  Fly   830 --LETNNIGEAPPESTTPAAPATVAVATD--------ESTAAPAATGGQEIVREG------QHHD 878
              :|...:.:...::|...|...|...:.        |...:....||...:|..      ..|.
 Worm   657 VVIENAEMVDQEMKNTGKKAINMVEFGSRLKKLKSELEGWKSNITVGGAHRIRRSTPSLADYAHI 721

  Fly   879 GQQVADEQDTEQQLAKTTMAVTTTTTSATTTTTSTTTTTTETPLTTTTMQPVEISLLDDSTTTTT 943
            .|........:..|.|...||  .....|....:|.....|...:..::..:.:.|...:|..|.
 Worm   722 FQNALKVGGVDDDLKKLMDAV--KDFEKTGKDAATKVKLKEVIASLNSLNSIGLQLSSFATPFTA 784

  Fly   944 -------------------TTPAPPVYFESSTVAS----TTIRSSTTMLPETTTASTQSPSEMPP 985
                               |||||.|   ||:.||    .:...|.|:.|..|.:.|.:...|
 Worm   785 IGQSFSALDAFFVSNGKIITTPAPIV---SSSGASQEGQKSAGGSMTLQPSQTVSVTTTEEPM-- 844

  Fly   986 TFMAPYPNELDHMQTNAQDNGTDVNVIIAITVSVIGVVALILLVAFLYLMRK-----RQKQTSYG 1045
                              |..|::.:.|.|...::.|.|||:.|...|...|     .::.|...
 Worm   845 ------------------DESTNLMIFIGIGCGIVLVSALIVAVVCFYKRNKIANDDMEQGTKIE 891

  Fly  1046 QRCRPVSLDAYSLDNVSV-------------LGSVRRKGRDMR--ASK--RTYGNAAFDDPSLRH 1093
            :......|.|....|:..             :...::||..::  |.|  :.:.....||
 Worm   892 KEKIARELAAQEAQNIEAEKKKKEIKDLEAKVDYEKQKGEKIKEEAEKEIQDHRKKVEDD----- 951

  Fly  1094 NLLTASELARFVERRSDVFEE---------------------FRDVPQIIARADEVPPGC----- 1132
                  :|.:|.:.||...|:                     ::....|:..|:..|...
 Worm   952 ------KLPKFYDIRSPTIEDATALEGDKGATNNGKLPLKAMYQFCKSILRIANLAPNNAIVESE 1010

  Fly  1133 --EDKNRYANVIPLPETRVVLQRQGDDD-------KTEYINANYVRGPRDAPNYYIACQAP---- 1184
              .:::||::|:...:.|:::    |:|       |.:||||||:..|..  |..|..|||
 Worm  1011 KYSEQDRYSDVLCGMDNRILI----DEDVCRRCYFKDQYINANYLELPNG--NRMILTQAPMSRT 1069

  Fly  1185 --------------------------LESTTSDFWRMIWEQQSRVIIQATDLSENGIERCAEYLP 1223
                                      |..|...|::.|.:..:.|:....|.:|.|:|:|:.|.|
 Worm  1070 EHFKPEKDKKRKNLYSLSDEEEEISYLVQTVDKFYQTIVQTGTEVVAMLCDFNEEGVEKCSSYFP 1134

  Fly  1224 PSATLDNHSSYGDYQVTLKHREVKDRYA---ISTLVLKRVDGEESRELT--HYWYK-WPEAGVPA 1282
                |:.......:.|.:....|:...|   :.|||:....||:.:..|  ||.|| |.|...|.
 Worm  1135 ----LEKDGKQKFHNVNVCTTNVQHPSADVVLRTLVITSYLGEKKKTHTVKHYSYKGWIEKNAPE 1195

  Fly  1283 EEAPIIAMLLEARSSLKSYSLEQANELREKSATLETSMDADGSKAEAGSTSSHEINGNISSRSGT 1347
            ....|:.:...||:|              ||
 Worm  1196 LPREILNIFRVARNS--------------KS---------------------------------- 1212

  Fly  1348 RSQQGPLTVHCSPGTGRTGTIIASDMA----IRSLETPKR-SVDIPQLVYYVRRGRASAVQTKEQ 1407
                  |.||||.|.||:...:.::..    ||||:|... ::|...|:..:|..|..|:.|..|
 Worm  1213 ------LVVHCSNGIGRSAAFVFAEFVYQKMIRSLDTTSTVNLDFLSLLTELRHSRPRAIHTPMQ 1271

  Fly  1408 YEF 1410
            ..|
 Worm  1272 LAF 1274

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42327	NP_001036706.2	PTPc	1134..1415	CDD:214550	75/325 (23%)
K09F6.3	NP_001342012.1	WSN	56..124	CDD:197734
		PTPc	992..1281	CDD:214550	78/347 (22%)