Protein Alignment CG42327 and Y48G1C.5

DIOPT Version :9

• Sequence 1: NP_001036706.2
• Gene: CG42327 / 41401
• FlyBaseID: FBgn0259227
• Length: 1429
• Species: Drosophila melanogaster
• Sequence 2: NP_490668.4
• Gene: Y48G1C.5 / 171595
• WormBaseID: WBGene00021678
• Length: 1161
• Species: Caenorhabditis elegans
• Alignment Length: 1391
• Identity: 253/1391 - (18%)
• Similarity: 427/1391 - (30%)
• Gaps: 431/1391 - (30%)

  Fly   137 SADTVKEESSTTTTSQLDQNPTNVTDKKSTEAQFKDERLSKEILSTTTEQILLTEKALQKYVVIT 201
            ::||.:||||......||..         ::.:.||:.     |.|..|::....:.:....:
 Worm    19 NSDTFEEESSFFNVMSLDPR---------SKREAKDDN-----LITAVERLQFASRLINAMYL-- 67

  Fly   202 NSPLRGEAQPEIKDKTSKSATSEKSTLPLKPVTIEVPSTTTEGVFNTTTTRSSDHGRSMQYSSTT 266
                    |.|:          .|.|:|...:|::        :|....  |.|...::.|||.
 Worm    68 --------QQEL----------TKGTIPSMNLTLD--------LFKYDF--SMDQLNAIDYSSL- 103

  Fly   267 EESSRSSPASVTPMKLIPLPMTSTPSSTTSTSTPLPTTAVSFASNENVIEESTSKSEVRQLPEKR 331
             ||           |||.|....:.......:....||.      ::|:..:....::::.|::.
 Worm   104 -ES-----------KLIALKELQSNIGDDVEADQFFTTV------KSVVHVAHDIGDLKKWPDET 150

  Fly   332 -----AKFISENSTNAQQLTLPNTAEVWSLAGMKAVPKAPLTTTTSVP---------LLNHTDLA 382
                 .|.|:::.::.  .||.....|||.:..:.   ...|:.|.:|         |....|..
 Worm   151 NFKADMKDITDSFSSV--TTLSEKLSVWSNSYTEI---EAFTSFTDIPKSHSALNDLLKKSQDFL 210

  Fly   383 NDIDMPLNKTELHKEKN-------------LLDWMN-IAMLPLTPENR-----TEFV--VRTTLD 426
            |.::.|  |..||..||             :.|.|| |:...:...||     .|.:  :|....
 Worm   211 NIVENP--KITLHGFKNNNSAASFFVLWPKVRDVMNFISSFKIVDINRGLRKLEEHMASIRNAFP 273

  Fly   427 ATEGATQATTEALVEETHSKSDITVGLEQDNVTTARTMPSTPDPGSMDLNMTTTTVRTQQLEVPL 491
            ..|......|...:.::......||||..               |::|:....:.:.|.......
 Worm   274 NQESKIHLQTIESIGQSLRTKKYTVGLPN---------------GAIDIGALNSQLATDAWARET 323

  Fly   492 VKKMSDAANAKLIEAVTEPQRETEAATEAATFVTLP------EKLATFGITARVDS----TQTEL 546
            ...|......:.|..:.|..|..|.......|.|:.      |:|....:...||.    .|...
 Worm   324 TDHMIFLRELETIWLLGEEVRNVERLLRKDRFSTISQLFNTIERLDIQSLNVLVDEAKVIAQCAK 388

  Fly   547 LNVTTAAAATESGEMSK-ANSTDT-----LSAMTSTTTTTARPMS--VEHVTPEQDMEAATSLAT 603
            ..:|||...|...|:|| |::.||     .|.:.|.........|  .|.:|..:||.  .|..|
 Worm   389 STLTTAPDFTNLEELSKIASNIDTELEQSKSILKSVMNQLVESKSGHAEVLTVCKDMN--NSNWT 451

  Fly   604 TA---------ATSSGTTEAAATSSTTAATPVVSEA--ATAAEASATSEATTAATLSVATTAAST 657
            ||         .|....|.:..|::.|...|.:.:.  ..|.|....|.:..|..|.|.:...|.
 Worm   452 TAEPCFNGVKKMTGLSLTMSRMTANATFLNPNLLKTLEKRAIEKINDSRSDIAQFLDVLSCLQSN 516

  Fly   658 TEIAMKATQISNIRDDNDDNSNDVIVATTKFPESEQAATTASVEPTTTSVSVRVAGEVSTSIRPE 722
            .|:......:|::.....|.         |||     ....:||....|||     .:::.::..
 Worm   517 KELDKIQKNLSDLNSFRADQ---------KFP-----PIVTAVEDALISVS-----SLNSGLKSL 562

  Fly   723 IIVTSTRNSTIVDTSTSATSVATPTQTEIAQISNEV-NLEAVTVKTRDGLSDTNELRTAEKTDNA 786
            .:..|.|.....|.::...:.|..|.: |...:.|: .||.|             ||.....| .
 Worm   563 ALYFSKRRKFASDKTSQFPNAAEHTNS-IGPAAQEIARLEDV-------------LRERANVD-I 612

  Fly   787 VNNSVAITESDLGAL-ATAVETNPTTTNSLLS------------DVSKLSKEHESSLETNNIGEA 838
            :.|...|.:.:|.|. ||..:.:......|::            |..|...:...|.:..:.|
 Worm   613 IKNHAQIVQRELAASGATLAQDDKDNLEKLVALGASLDVMFVQLDAWKSGIKKSDSTKFVDYG-- 675

  Fly   839 PPESTTPAAPATVAVATDESTAAPAATGG-----------QEIVRE-------GQHHDGQQVADE 885
                         .|.|:......|..||           .|:|::       |:..|..:..|:
 Worm   676 -------------YVFTEAKKVDWANLGGLMGLEKSLEKLVELVKDVGNKKSLGEVQDALKSLDD 727

  Fly   886 QDTEQQLAKTTMAVTTTTTSATTTTTSTTTTTTETPLTTTTMQPVEISLLDDSTTTTTTTPAPPV 950
            ...|....:..:.......:|.....|...    .||.|..:.|
 Worm   728 GGLEFSSFQNRLDEPKKALAALDLFFSNLF----KPLPTAILPP--------------------- 767

  Fly   951 YFESSTVASTTIRSSTTMLPETTTASTQSPSEMPPTFMAPYPNELDHMQTNAQDNGTDVNVIIAI 1015
                               |:...:....|   ||             ||:.|      .||:|:
 Worm   768 -------------------PDLGNSEKNGP---PP-------------QTHGQ------YVILAL 791

  Fly  1016 TVSVI--GVVALILLVAFLY-LMRKRQKQTSY--GQRCRPVSLDAYSLDNVSVLGSVRRKGRDMR 1075
            .|.||  .::|...|....| ::...:|:..|  .|....|.::.....|.
 Worm   792 IVIVIICAIIAYFCLTPNGYKILDSEEKEKLYPPNQMISRVDVNETRFSNF-------------- 842

  Fly  1076 ASKRTYGNAAFDDPSLRHNLLTASELARFVERRSDVFEEFRDVP-QIIARADEVPPGCE-DKNRY 1138
              .:|:.                ::::.||.|:.:....|.:|| .:....|:....|. ....:
 Worm   843 --LKTFN----------------TQISDFVTRKRNCTSVFENVPNNLEITGDDFAQFCGLQGGNH 889

  Fly  1139 ANVIPLPETRVVLQRQGDDDKTEYIN--ANYVRGPRDAPNYYIACQAPLESTTSD------FWRM 1195
            ....|:.........||:......::  ..:|..|  ||      |.|::..:||      ||..
 Worm   890 CQCDPVSYESSKKNGQGESSHVVELDNGLKFVLMP--AP------QLPVDKKSSDILAIAAFWES 946

  Fly  1196 IWEQQSRVIIQATDLSE-------NGIERCAEYLPPSATLDNHSSYGDYQVT----LKHREVKDR 1249
            :...:...|:...|.:|       |.: .|..|.|  ..||......|..:|    :....:|.|
 Worm   947 VKLNKPSTIVMLCDFAEIDHFIGANKV-NCDRYFP--TELDEKLILADLTITCTKSISKPLLKTR 1008

  Fly  1250 YAISTLVLKRVDGEESRELTHYWYK-WPEAGVP--AEEAPIIAMLLEARSSLKSYSLEQANELRE 1311
            ..:.|...||     ::|:|||.|. |||...|  |||...:..|:
 Worm  1009 QLLLTFGKKR-----TQEVTHYQYTGWPEHMGPKDAEEIRYLLKLV------------------- 1049

  Fly  1312 KSATLETSMDADGSKAEAGSTSSHEINGNISSRSGTRSQQGPLTVHCSPGTGRTGTIIASDMAIR 1376
                                               |.|:: |:.|.|:.|.||:...:..:...:
 Worm  1050 -----------------------------------TDSER-PVFVVCNTGGGRSAAFVLIESLFQ 1078

  Fly  1377 SLETPKR-SVDIPQLVYYVRRGRASA 1401
            ::.|.:. .::...|:...|..|..|
 Worm  1079 AINTSETGEINYRSLIEQTRSKRKCA 1104

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42327	NP_001036706.2	PTPc	1134..1415	CDD:238006	55/291 (19%)
		Y_phosphatase	1134..1415	CDD:278528	55/291 (19%)
Y48G1C.5	NP_490668.4	WSN	47..111	CDD:280385	20/111 (18%)
		PTPc	<940..1085	CDD:304379	40/207 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0789
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900